STRINGSTRING
GMDG_00109 GMDG_00109 GMDG_01346 GMDG_01346 SLX1 SLX1 GMDG_07730 GMDG_07730 GMDG_02480 GMDG_02480 GMDG_08149 GMDG_08149 GMDG_02083 GMDG_02083 GMDG_00598 GMDG_00598 GMDG_03391 GMDG_03391 GMDG_03916 GMDG_03916 GMDG_04870 GMDG_04870
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GMDG_00109NTF2 domain-containing protein. (123 aa)
GMDG_01346Ubiquitin-40S ribosomal protein S27a. (156 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (329 aa)
GMDG_07730Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2459 aa)
GMDG_02480Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (608 aa)
GMDG_08149Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (849 aa)
GMDG_02083BZIP domain-containing protein. (212 aa)
GMDG_00598Asparaginyl-tRNA synthetase. (598 aa)
GMDG_03391Polyubiquitin. (381 aa)
GMDG_03916BZIP domain-containing protein. (409 aa)
GMDG_04870DRMBL domain-containing protein. (874 aa)
Your Current Organism:
Pseudogymnoascus destructans
NCBI taxonomy Id: 658429
Other names: Geomyces destructans 20631-21, P. destructans 20631-21, Pseudogymnoascus destructans 20631-21
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