60 items (Pseudogymnoascus destructans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GMDG_00134	Uncharacterized protein. (1673 aa)
	GMDG_08034	CCHC-type domain-containing protein. (427 aa)
	GMDG_01774	Uncharacterized protein. (108 aa)
	GMDG_07489	Uncharacterized protein. (516 aa)
	GMDG_01879	Uncharacterized protein. (237 aa)
	GMDG_01907	Uncharacterized protein. (431 aa)
	GMDG_07500	CCHC-type domain-containing protein. (287 aa)
	GMDG_07538	CCHC-type domain-containing protein. (380 aa)
	GMDG_07523	DNA polymerase. (1102 aa)
	GMDG_07234	CCHC-type domain-containing protein. (390 aa)
	GMDG_07452	Uncharacterized protein. (447 aa)
	GMDG_07422	CCHC-type domain-containing protein. (300 aa)
	GMDG_01292	CCHC-type domain-containing protein. (437 aa)
	GMDG_04440	Uncharacterized protein. (564 aa)
	GMDG_08710	Uncharacterized protein. (91 aa)
	GMDG_08652	Uncharacterized protein. (121 aa)
	GMDG_08706	CCHC-type domain-containing protein. (323 aa)
	GMDG_08682	Uncharacterized protein. (351 aa)
	GMDG_03757	Uncharacterized protein. (460 aa)
	GMDG_03719	Amino_oxidase domain-containing protein. (581 aa)
	GMDG_08675	Chromo domain-containing protein. (210 aa)
	GMDG_00597	DNA ligase. (930 aa)
	GMDG_03508	CCHC-type domain-containing protein. (393 aa)
	GMDG_08668	CCHC-type domain-containing protein. (355 aa)
	GMDG_08665	Chromo domain-containing protein. (198 aa)
	GMDG_08621	Uncharacterized protein. (95 aa)
	GMDG_02856	Uncharacterized protein. (451 aa)
	GMDG_02760	Uncharacterized protein. (301 aa)
	GMDG_03022	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (912 aa)
	GMDG_03083	CCHC-type domain-containing protein. (210 aa)
	GMDG_02759	Uncharacterized protein. (184 aa)
	GMDG_02762	Uncharacterized protein. (364 aa)
	GMDG_08339	Uncharacterized protein. (67 aa)
	GMDG_08532	CCHC-type domain-containing protein. (393 aa)
	GMDG_02005	Zds_C domain-containing protein. (919 aa)
	GMDG_02480	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (608 aa)
	GMDG_04883	Uncharacterized protein. (472 aa)
	GMDG_04669	DNA ligase. (883 aa)
	GMDG_04904	CCHC-type domain-containing protein. (379 aa)
	GMDG_04371	Chromo domain-containing protein. (118 aa)
	GMDG_08717	Uncharacterized protein. (210 aa)
	GMDG_04437	Uncharacterized protein. (661 aa)
	GMDG_04500	CCHC-type domain-containing protein. (410 aa)
	GMDG_05031	Uncharacterized protein. (408 aa)
	GMDG_01806	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (669 aa)
	GMDG_08909	Chromo domain-containing protein. (110 aa)
	GMDG_06067	Uncharacterized protein. (228 aa)
	GMDG_08061	DNA polymerase. (1445 aa)
	GMDG_05775	Uncharacterized protein. (135 aa)
	GMDG_05725	CCHC-type domain-containing protein. (124 aa)
	GMDG_08809	Uncharacterized protein. (115 aa)
	GMDG_05244	CCHC-type domain-containing protein. (361 aa)
	GMDG_05075	Uncharacterized protein. (237 aa)
	GMDG_05309	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (546 aa)
	GMDG_05314	Uncharacterized protein. (100 aa)
	GMDG_05459	CCHC-type domain-containing protein. (300 aa)
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
	GMDG_06622	CCHC-type domain-containing protein. (406 aa)
	GMDG_05905	Uncharacterized protein. (122 aa)
	GMDG_01462	Uncharacterized protein. (286 aa)

Your Current Organism:

Pseudogymnoascus destructans

NCBI taxonomy Id: 658429
Other names: Geomyces destructans 20631-21, P. destructans 20631-21, Pseudogymnoascus destructans 20631-21

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FEN1	GMDG_00134	L8FSI2	L8FMQ8	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.974
FEN1	GMDG_00597	L8FSI2	L8G7X3	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA ligase.	0.980
FEN1	GMDG_01806	L8FSI2	L8G119	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.	0.846
FEN1	GMDG_01907	L8FSI2	L8FY53	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.847
FEN1	GMDG_02480	L8FSI2	L8G203	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.856
FEN1	GMDG_03022	L8FSI2	L8G521	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.999
FEN1	GMDG_03757	L8FSI2	L8G8K4	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.840
FEN1	GMDG_04669	L8FSI2	L8GC84	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA ligase.	0.977
FEN1	GMDG_05309	L8FSI2	L8FRB4	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	0.938
FEN1	GMDG_07489	L8FSI2	L8FYF6	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.969
FEN1	GMDG_07523	L8FSI2	L8FXI4	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA polymerase.	0.991
FEN1	GMDG_08061	L8FSI2	L8G1P2	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA polymerase.	0.899
GMDG_00134	FEN1	L8FMQ8	L8FSI2	Uncharacterized protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.974
GMDG_00134	GMDG_00597	L8FMQ8	L8G7X3	Uncharacterized protein.	DNA ligase.	0.594
GMDG_00134	GMDG_01806	L8FMQ8	L8G119	Uncharacterized protein.	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.	0.779
GMDG_00134	GMDG_01907	L8FMQ8	L8FY53	Uncharacterized protein.	Uncharacterized protein.	0.872
GMDG_00134	GMDG_02480	L8FMQ8	L8G203	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.978
GMDG_00134	GMDG_03022	L8FMQ8	L8G521	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.769
GMDG_00134	GMDG_03757	L8FMQ8	L8G8K4	Uncharacterized protein.	Uncharacterized protein.	0.784
GMDG_00134	GMDG_04669	L8FMQ8	L8GC84	Uncharacterized protein.	DNA ligase.	0.545