30 items (Pseudogymnoascus destructans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GMDG_08467	Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (150 aa)
	GMDG_00990	Uncharacterized protein. (56 aa)
	GMDG_05046	Uncharacterized protein. (857 aa)
	GMDG_00996	Mitochondrial import receptor subunit TOM40. (356 aa)
	GMDG_00097	Autophagy-related protein. (121 aa)
	GMDG_00132	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (253 aa)
	GMDG_05048	Uncharacterized protein. (631 aa)
	GMDG_01346	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	GMDG_01147	Zn(2)-C6 fungal-type domain-containing protein. (774 aa)
	GMDG_01796	USP domain-containing protein; Belongs to the peptidase C19 family. (550 aa)
	GMDG_07630	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (259 aa)
	GMDG_01539	Uncharacterized protein. (514 aa)
	GMDG_07650	CMGC/CK2 protein kinase. (284 aa)
	GMDG_02009	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. (146 aa)
	GMDG_02442	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2941 aa)
	GMDG_02083	BZIP domain-containing protein. (212 aa)
	GMDG_02435	DJ-1_PfpI domain-containing protein. (287 aa)
	GMDG_08474	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (925 aa)
	GMDG_02370	Uncharacterized protein. (216 aa)
	GMDG_08471	Uncharacterized protein. (154 aa)
	GMDG_08516	Uncharacterized protein. (1051 aa)
	MDM34	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (571 aa)
	GMDG_03391	Polyubiquitin. (381 aa)
	GMDG_03916	BZIP domain-containing protein. (409 aa)
	GMDG_03903	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (328 aa)
	GMDG_04102	Uncharacterized protein. (176 aa)
	GMDG_03960	ULK/ULK protein kinase. (964 aa)
	GMDG_04245	UBIQUITIN_CONJUGAT_2 domain-containing protein. (141 aa)
	GMDG_04255	Uncharacterized protein. (589 aa)
	GMDG_04861	TPR_REGION domain-containing protein. (651 aa)

Your Current Organism:

Pseudogymnoascus destructans

NCBI taxonomy Id: 658429
Other names: Geomyces destructans 20631-21, P. destructans 20631-21, Pseudogymnoascus destructans 20631-21

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GMDG_00097	GMDG_01346	L8FPV1	L8FSG6	Autophagy-related protein.	Ubiquitin-40S ribosomal protein S27a.	0.706
GMDG_00097	GMDG_02009	L8FPV1	L8FYQ8	Autophagy-related protein.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	0.942
GMDG_00097	GMDG_02083	L8FPV1	L8G2Z5	Autophagy-related protein.	BZIP domain-containing protein.	0.706
GMDG_00097	GMDG_02442	L8FPV1	L8G1S3	Autophagy-related protein.	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	0.637
GMDG_00097	GMDG_03391	L8FPV1	L8G786	Autophagy-related protein.	Polyubiquitin.	0.848
GMDG_00097	GMDG_03916	L8FPV1	L8G7Y4	Autophagy-related protein.	BZIP domain-containing protein.	0.706
GMDG_00097	GMDG_03960	L8FPV1	L8GBH9	Autophagy-related protein.	ULK/ULK protein kinase.	0.996
GMDG_00097	GMDG_04102	L8FPV1	L8G9T9	Autophagy-related protein.	Uncharacterized protein.	0.481
GMDG_00097	GMDG_04861	L8FPV1	L8GCQ8	Autophagy-related protein.	TPR_REGION domain-containing protein.	0.746
GMDG_00097	GMDG_05046	L8FPV1	L8FMU0	Autophagy-related protein.	Uncharacterized protein.	0.938
GMDG_00097	GMDG_07630	L8FPV1	L8FYA9	Autophagy-related protein.	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	0.936
GMDG_00097	GMDG_08474	L8FPV1	L8G435	Autophagy-related protein.	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.783
GMDG_00097	GMDG_08516	L8FPV1	L8G6S7	Autophagy-related protein.	Uncharacterized protein.	0.969
GMDG_00132	GMDG_03903	L8FPY0	L8G8B3	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.979
GMDG_00132	GMDG_07650	L8FPY0	L8FYC7	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	CMGC/CK2 protein kinase.	0.979
GMDG_00132	MDM34	L8FPY0	L8G785	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	0.854
GMDG_00990	GMDG_00996	L8FMR5	L8FP18	Uncharacterized protein.	Mitochondrial import receptor subunit TOM40.	0.989
GMDG_00990	GMDG_04102	L8FMR5	L8G9T9	Uncharacterized protein.	Uncharacterized protein.	0.977
GMDG_00990	GMDG_05048	L8FMR5	L8FQ66	Uncharacterized protein.	Uncharacterized protein.	0.916
GMDG_00990	GMDG_08471	L8FMR5	L8G6G4	Uncharacterized protein.	Uncharacterized protein.	0.998