STRINGSTRING
recF recF gyrB gyrB hupA hupA atpD atpD sthA sthA aceB aceB aceA aceA hmp hmp DSJ_07945 DSJ_07945 DSJ_08340 DSJ_08340 cydB cydB kdsB kdsB aldB aldB gabD gabD DSJ_11620 DSJ_11620 rcsA rcsA DSJ_12700 DSJ_12700 sodC sodC araC araC DSJ_13610 DSJ_13610 DSJ_13710 DSJ_13710 uxaB uxaB esaR esaR pntB pntB pntA pntA hrpA hrpA yeaG yeaG fadR fadR fadD fadD fadH fadH DSJ_15335 DSJ_15335 fadJ fadJ fadE fadE gldA gldA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
recFDNA replication/repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (361 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (802 aa)
hupADNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (90 aa)
atpDF0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (465 aa)
sthANAD(P)(+) transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (466 aa)
aceBMalate synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. (532 aa)
aceAIsocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
hmpNitric oxide dioxygenase; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. (394 aa)
DSJ_07945Sugar-phosphatase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
DSJ_08340Cytochrome d terminal oxidase subunit 1; Part of the aerobic respiratory chain; catalyzes the ubiquinol to ubiquinone; Derived by automated computational analysis using gene prediction method: Protein Homology. (523 aa)
cydBCytochrome d ubiquinol oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (249 aa)
aldBAldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (506 aa)
gabDSuccinate-semialdehyde dehydrogenase (NADP(+)); Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (485 aa)
DSJ_11620AsnC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
rcsAHelix-turn-helix transcriptional regulator; Component of the Rcs signaling system, which controls transcription of numerous genes. Binds to DNA to regulate expression of genes. (211 aa)
DSJ_12700ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
sodCSuperoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (172 aa)
araCDNA-binding transcriptional regulator AraC; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
DSJ_13610AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (115 aa)
DSJ_13710Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the catalase family. (488 aa)
uxaBAltronate oxidoreductase; Catalyzes the formation of D-tagaturonate from D-altronate; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
esaRLuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
pntBNAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (462 aa)
pntANAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. (510 aa)
hrpAATP-dependent RNA helicase HrpA; Derived by automated computational analysis using gene prediction method: Protein Homology. (1299 aa)
yeaGPrkA family serine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (644 aa)
fadRFatty acid metabolism regulator; Multifunctional regulator of fatty acid metabolism. (239 aa)
fadDlong-chain-fatty-acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa)
fadHHypothetical protein; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (673 aa)
DSJ_15335Glycerol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
fadJMultifunctional fatty acid oxidation complex subunit alpha; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (706 aa)
fadEacyl-CoA dehydrogenase; Functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (815 aa)
gldAPTS-dependent dihydroxyacetone kinase operon transcriptional regulator DhaR; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
Your Current Organism:
Pantoea stewartii
NCBI taxonomy Id: 660596
Other names: P. stewartii subsp. stewartii DC283, Pantoea stewartii subsp. stewartii DC283, Pantoea stewartii subsp. stewartii str. DC283, Pantoea stewartii subsp. stewartii strain DC283
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.