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fumC fumC sfcA sfcA LLO_0659 LLO_0659 yccX yccX atoB atoB sfcA-2 sfcA-2 gloB gloB poxB poxB odp odp LLO_1518 LLO_1518 odpA odpA lpd lpd aceF aceF aceE aceE yfcY yfcY LLO_1948 LLO_1948 LLO_1949 LLO_1949 ppsA ppsA accA accA LLO_2332 LLO_2332 accD accD ackA ackA LLO_2361 LLO_2361 ywdH ywdH LLO_2561 LLO_2561 accB accB accC accC mdh mdh capP capP pykA pykA acsB acsB LLO_3427 LLO_3427
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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fumCFumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)
sfcAMalate dehydrogenase, (decarboxylating, NAD-requiring) (malic enzyme); Equals llo0429. (569 aa)
LLO_0659Putative NADP-dependent malic enzyme; Equals llo0659. (474 aa)
yccXAcylphosphatase; Equals llo1028. (91 aa)
atoBEquals llo1078; similar to acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
sfcA-2Malate oxidoreductase; Equals llo1147. (572 aa)
gloBPutative hydroxyacylglutathione hydrolase (glyoxalase II); Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (254 aa)
poxBPyruvate dehydrogenase (pyruvate oxidase), thiamin-dependent, FAD-binding; Equals llo1357; Belongs to the TPP enzyme family. (575 aa)
odpBranched-chain alpha-keto acid dehydrogenase subunit E2; Equals llo1517; pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase). (370 aa)
LLO_1518Equals llo1518; similar to pyruvate dehydrogenase E1 (beta subunit). (324 aa)
odpAPyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (357 aa)
lpdLipoamide dehydrogenase, E3 component is part of three enzyme complexes; Equals llo1759. (479 aa)
aceFPyruvate dehydrogenase (dihydrolipoyltransacetylase component) E2p; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (541 aa)
aceEPyruvate dehydrogenase (decarboxylase component) E1p; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa)
yfcYbeta-ketoacyl-CoA thiolase, anaerobic, subunit; Equals llo1817; similar to beta-Subunit of fatty acid oxidation complex, 3-keto-acyl-CoA-thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (439 aa)
LLO_1948Equals llo1948; Simiar to 2-oxoglutarate ferredoxin oxidoreductase beta subunit. (322 aa)
LLO_1949Equals llo1949; similar to 2-oxoglutarate ferredoxin oxidoreductase alpha subunit. (602 aa)
ppsAPutative phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa)
accAacetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa)
LLO_2332Equals llo2332; similar to aldehyde dehydrogenase. (506 aa)
accDPutative acetyl-CoA carboxylase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (287 aa)
ackAAcetate kinase (Acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (391 aa)
LLO_2361Putative phosphate acetyl/butaryl transferase; Equals llo2361. (465 aa)
ywdHPutative aldehyde dehydrogenase ywdH; Equals llo2488; Belongs to the aldehyde dehydrogenase family. (456 aa)
LLO_2561Equals llo2561; similar to NADP-dependent malic enzyme. (407 aa)
accBacetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (161 aa)
accCBiotin carboxylase (A subunit of acetyl-CoA carboxylase); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (446 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
capPPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (771 aa)
pykAPyruvate kinase II; Equals llo3264; similar to pyruvate kinase II PykA, glucose stimulated. (472 aa)
acsBPutative acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (626 aa)
LLO_3427Equals llo3427; similar to lactoylglutathione lyase. (146 aa)
Your Current Organism:
Legionella longbeachae
NCBI taxonomy Id: 661367
Other names: L. longbeachae NSW150, Legionella longbeachae NSW150, Legionella longbeachae str. NSW150, Legionella longbeachae strain NSW150
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