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ANP63488.1 ANP63488.1 gtaB_1 gtaB_1 glmS glmS murQ murQ nagZ nagZ ANP63971.1 ANP63971.1 crr crr nagA nagA ptsG_1 ptsG_1 ANP64042.1 ANP64042.1 glgC glgC nagK_1 nagK_1 ptsG_2 ptsG_2 ANP65455.1 ANP65455.1 glmM glmM ANP65681.1 ANP65681.1 ANP65682.1 ANP65682.1 ANP65683.1 ANP65683.1 murA murA galU galU pgi pgi glmU glmU scrK scrK glgC-2 glgC-2 ANP67155.1 ANP67155.1 ANP67226.1 ANP67226.1 ANP67455.1 ANP67455.1 murQ-2 murQ-2 murP murP nagB nagB ANP67950.1 ANP67950.1 murB murB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANP63488.1UDP-glucose 6-dehydrogenase; Catalyzes the formation of UDP-glucuronate from UDP-glucose; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
gtaB_1UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
glmSGlutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (610 aa)
murQN-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. (309 aa)
nagZbeta-N-acetylhexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (327 aa)
ANP63971.1beta-N-acetylhexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (883 aa)
crrPTS glucose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (169 aa)
nagAN-acetylglucosamine-6-phosphate deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
ptsG_1PTS glucose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
ANP64042.1Phosphoglucomutase, alpha-D-glucose phosphate-specific; Catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (405 aa)
nagK_1N-acetylglucosamine kinase; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. (302 aa)
ptsG_2PTS glucose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
ANP65455.1Chitinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (848 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (446 aa)
ANP65681.1N-acetylglucosamine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
ANP65682.1Beta-hexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (639 aa)
ANP65683.1N,N'-diacetylchitobiose phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (802 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (418 aa)
galUUTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (550 aa)
glmUUDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (453 aa)
scrKAminoimidazole riboside kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
glgC-2Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (405 aa)
ANP67155.1UDP-glucose 4-epimerase GalE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (338 aa)
ANP67226.1Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 1 family. (405 aa)
ANP67455.1Phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (564 aa)
murQ-2N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. (300 aa)
murPPTS N-acetylmuramic acid transporter subunits IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (266 aa)
ANP67950.1Chitinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (848 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (347 aa)
Your Current Organism:
Vibrio alginolyticus
NCBI taxonomy Id: 663
Other names: ATCC 17749, Beneckea alginolytica, CAIM 516, CCUG 13445, CCUG 16315, CCUG 4989, CIP 103336, CIP 75.3, DSM 2171, IFO 15630, LMG 4409, LMG:4409, NBRC 15630, NCCB 71013, NCCB 77003, NCTC 12160, Oceanomonas alginolytica, Pseudomonas creosotensis, V. alginolyticus, Vibrio sp. PeIg0901
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