STRINGSTRING
REG_1936 REG_1936 rapZ rapZ csrA csrA rplY rplY REG_0111 REG_0111 typA typA rph rph REG_0127 REG_0127 rpsL rpsL rpsG rpsG rpsJ rpsJ rplC rplC rplD rplD rplW rplW rplB rplB rpsS rpsS rplV rplV rpsC rpsC rplP rplP rpsQ rpsQ rplN rplN rplX rplX rplE rplE rpsN rpsN rpsH rpsH rplF rplF rplR rplR rpsE rpsE rplO rplO rpsM rpsM rpsK rpsK rpsD rpsD REG_0187 REG_0187 rnr rnr rplU rplU alaS alaS rpmE rpmE proQ proQ rnc rnc era era rlmL rlmL mnmA mnmA rne rne rluC rluC REG_1937 REG_1937 tyrS tyrS ksgA ksgA tmcA tmcA nusB nusB rplI rplI rpsR rpsR rpsF rpsF rpsT rpsT ileS ileS REG_0867 REG_0867 rluB rluB infA infA REG_0955 REG_0955 REG_0995 REG_0995 REG_1035 REG_1035 REG_1039 REG_1039 pcnB pcnB dusB_fis dusB_fis rlmB rlmB deaD deaD pnp pnp rpsO rpsO rng rng REG_1240 REG_1240 rhlB rhlB rho rho rsgA rsgA rnhB rnhB rluA rluA nusA nusA truB truB cca cca rnpA rnpA rluD rluD rplK rplK rplA rplA rplJ rplJ gltX gltX dbpA dbpA rnb rnb ffh ffh rplT rplT pheS pheS pheT pheT rsmB rsmB REG_1663 REG_1663 rimN rimN trmJ trmJ thiI thiI smpB smpB rlmN rlmN rpsA rpsA dusA dusA REG_1923 REG_1923
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
REG_1936Hypothetical protein; COG2961; similar to AA sequence EcoGene EG12234; similar to AA sequence GI 77963009. (162 aa)
rapZP-loop ATPase domain-containing hypothetical protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily. (288 aa)
csrACarbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). (68 aa)
rplY50S ribosomal subunit protein L25 (general stress protein Ctc); This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. (99 aa)
REG_0111Nucleoid-associated protein; COG3081; similar to AA sequence EcoGene EG12048; similar to AA sequence GI 77962645. (333 aa)
typAPutative membrane GTPase involved in stress response; COG1217; similar to AA sequence EcoGene EG11837; similar to AA sequence GI 157373111. (613 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (242 aa)
REG_0127Hypothetical protein; COG1561; similar to AA sequence EcoGene EG11192; similar to AA sequence GI 77976753. (287 aa)
rpsL30S ribosomal subunit protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (124 aa)
rpsG30S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
rpsJ30S ribosomal subunit protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (132 aa)
rplC50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (258 aa)
rplD50S ribosomal subunit protein L4; Forms part of the polypeptide exit tunnel. (201 aa)
rplW50S ribosomal subunit protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (100 aa)
rplB50S ribosomal subunit protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (275 aa)
rpsS30S ribosomal subunit protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
rplV50S ribosomal subunit protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (125 aa)
rpsC30S ribosomal subunit protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (246 aa)
rplP50S ribosomal subunit protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (136 aa)
rpsQ30S ribosomal subunit protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (85 aa)
rplN50S ribosomal subunit protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (123 aa)
rplX50S ribosomal subunit protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (104 aa)
rplE50S ribosomal subunit protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa)
rpsN30S ribosomal subunit protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (108 aa)
rpsH30S ribosomal subunit protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
rplF50S ribosomal subunit protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa)
rplR50S ribosomal subunit protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (117 aa)
rpsE30S ribosomal subunit protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (166 aa)
rplO50S ribosomal subunit protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (195 aa)
rpsM30S ribosomal subunit protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (118 aa)
rpsK30S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa)
rpsD30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (206 aa)
REG_0187Hypothetical protein; COG4680; similar to AA sequence EcoGene EG12725; similar to AA sequence GI 162958024. (63 aa)
rnrExoribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily. (812 aa)
rplU50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (103 aa)
alaSAlanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. (893 aa)
rpmE50S ribosomal protein L31; Binds the 23S rRNA. (71 aa)
proQPutative structural transport element; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. (212 aa)
rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (235 aa)
eraGTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (310 aa)
rlmL23S rRNA m(2)G2445 methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. (771 aa)
mnmAPutative tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs; Belongs to the MnmA/TRMU family. (367 aa)
rneRibonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1017 aa)
rluC23S rRNA pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (294 aa)
REG_1937Hypothetical protein; COG2961; similar to AA sequence EcoGene EG12234; similar to AA sequence GI 152972373. (91 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (432 aa)
ksgAS-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (280 aa)
tmcAPutative ATPase and acetyltransferase domain protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (684 aa)
nusBTranscription termination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (182 aa)
rplI50S ribosomal subunit protein L9; Binds to the 23S rRNA. (150 aa)
rpsR30S ribosomal subunit protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (75 aa)
rpsF30S ribosomal subunit protein S6; Binds together with S18 to 16S ribosomal RNA. (133 aa)
rpsT30S ribosomal subunit protein S20; Binds directly to 16S ribosomal RNA. (87 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (938 aa)
REG_0867dsRNA-binding putative translation factor; COG0009; similar to AA sequence EcoGene EG12967; similar to AA sequence GI 22125943; Belongs to the SUA5 family. (196 aa)
rluB23S rRNA pseudouridylate synthase; COG1187; similar to AA sequence EcoGene EG12433; similar to AA sequence GI 77961373; Belongs to the pseudouridine synthase RsuA family. (291 aa)
infATranslation initiation factor 1 (IF-1); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa)
REG_0955Putative RNA-binding protein; COG1534; similar to AA sequence EcoGene EG12794; similar to AA sequence GI 77958783. (97 aa)
REG_0995HicA-like addiction module; N terminal truncation; similar to AA sequence GI 37524708. (68 aa)
REG_1035Group II intron encoded reverse transcriptase; COG3344; similar to AA sequence GI 156973402. (508 aa)
REG_1039Hypothetical protein; N terminal extension; COG4680; similar to AA sequence GI 91783283. (106 aa)
pcnBpoly(A) polymerase I; COG0617; similar to AA sequence EcoGene EG10690; similar to AA sequence GI 22124701. (471 aa)
dusB_fisCOG0042; similar to AA sequence EcoGene EG11311,EG10317; similar to AA sequence GI 77961459. (440 aa)
rlmB23S rRNA (guanosine-2'-O-)-methyltransferase; COG0566; similar to AA sequence EcoGene EG12483; similar to AA sequence GI 22124552. (251 aa)
deaDDEAD-box RNA helicase; COG0513; similar to AA sequence EcoGene EG10215; similar to AA sequence GI 21957415. (635 aa)
pnpPolynucleotide phosphorylase/polyadenylase; COG1185; similar to AA sequence EcoGene EG10743; similar to AA sequence GI 22124608. (698 aa)
rpsO30S ribosomal subunit protein S15; COG0184; similar to AA sequence EcoGene EG10914; similar to AA sequence GI 2462715. (89 aa)
rngCOG1530; similar to AA sequence EcoGene EG11299; similar to AA sequence GI 156935764. (489 aa)
REG_1240Putative ribonuclease; Similar to AA sequence GI 77973444. (164 aa)
rhlBATP-dependent RNA helicase; COG0513; similar to AA sequence EcoGene EG10844; similar to AA sequence GI 77977096. (431 aa)
rhoTranscription termination factor; COG1158; similar to AA sequence EcoGene EG10845; similar to AA sequence GI 62182392. (460 aa)
rsgARibosome small subunit-dependent GTPase A; COG1162; similar to AA sequence EcoGene EG12479; similar to AA sequence GI 77976478. (366 aa)
rnhBRibonuclease HII; COG0164; similar to AA sequence EcoGene EG10861; similar to AA sequence GI 77957703. (224 aa)
rluA23S rRNA and tRNA pseudouridine synthase; COG0564; similar to AA sequence EcoGene EG12609; similar to AA sequence GI 22127552. (212 aa)
nusATranscription termination/antitermination L factor; COG0195; similar to AA sequence EcoGene EG10665; similar to AA sequence GI 123440812. (506 aa)
truBtRNA pseudouridine synthase; COG0130; similar to AA sequence EcoGene EG11177; similar to AA sequence GI 22124604. (310 aa)
ccaCOG0617; similar to AA sequence EcoGene EG10136; similar to AA sequence GI 77962302. (462 aa)
rnpARNase P protein component; COG0594; similar to AA sequence EcoGene EG10862; similar to AA sequence GI 209909427. (114 aa)
rluD23S rRNA pseudouridine synthase; COG0564; similar to AA sequence EcoGene EG12098; similar to AA sequence GI 45440505. (325 aa)
rplK50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (142 aa)
rplA50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (230 aa)
rplJ50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (186 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (435 aa)
dbpAATP-dependent RNA helicase specific for 23S rRNA; COG0513; similar to AA sequence EcoGene EG10210; similar to AA sequence GI 22126413; Belongs to the DEAD box helicase family. (464 aa)
rnbRibonuclease II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction. (653 aa)
ffhSignal Recognition Particle (SRP) component with 4.5S RNA (ffs); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex [...] (453 aa)
rplT50S ribosomal subunit protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa)
pheSPhenylalanine tRNA synthetase alpha subunit; COG0016; similar to AA sequence EcoGene EG10709; similar to AA sequence GI 123442193; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (333 aa)
pheTPhenylalanine tRNA synthetase beta subunit; COG0072; similar to AA sequence EcoGene EG10710; similar to AA sequence GI 77975256; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (808 aa)
rsmB16S rRNA m5C967 methyltransferase (SAM-dependent); Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (390 aa)
REG_1663Addiction module toxin; COG2026; similar to AA sequence EcoGene EG11131; similar to AA sequence GI 211638890. (95 aa)
rimNPutative ribosome maturation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. (189 aa)
trmJPutative RNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (260 aa)
thiISulfurtransferase required for thiamine and 4-thiouridine biosynthesis; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (486 aa)
smpBTrans-translation protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switch [...] (175 aa)
rlmNHypothetical protein in radical SAM superfamily; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (378 aa)
rpsA30S ribosomal subunit protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (551 aa)
dusAtRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (344 aa)
REG_1923Addiction module relE-like toxin; COG2026; similar to AA sequence GI 123440880. (96 aa)
Your Current Organism:
Regiella insecticola
NCBI taxonomy Id: 663321
Other names: C. Regiella insecticola LSR1, Candidatus Regiella insecticola LSR1, Candidatus Regiella insecticola str. LSR1, Candidatus Regiella insecticola strain LSR1
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.