(38 nodes) Ubiquitin-dependent ERAD pathway network (Trichophyton benhamiae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ARB_04009	Ubiquitin conjugating enzyme (UbcJ), putative; Belongs to the ubiquitin-conjugating enzyme family. (245 aa)
	ARB_04606	N-acetyltransferase domain-containing protein. (178 aa)
	ARB_04655	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (725 aa)
	ARB_04656	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (364 aa)
	ARB_03964	ANK_REP_REGION domain-containing protein. (564 aa)
	ARB_04928	RING finger membrane protein. (1645 aa)
	ARB_05246	Uncharacterized protein. (418 aa)
	ARB_05266	Uncharacterized protein; Belongs to the heat shock protein 70 family. (790 aa)
	ARB_05653	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (704 aa)
	ARB_06104	Uncharacterized protein. (220 aa)
	ARB_06109	AZUL domain-containing protein. (761 aa)
	ARB_06436	J domain-containing protein. (449 aa)
	ARB_06440	RING-type domain-containing protein. (821 aa)
	ARB_06493	Misfolded glycoproteins degradation protein Yos9, putative. (580 aa)
	ARB_06748	Uncharacterized protein. (411 aa)
	ARB_06765	Uncharacterized protein. (380 aa)
	ARB_07033	Uncharacterized protein. (375 aa)
	ARB_07299	UBX domain protein. (364 aa)
	ARB_07436	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (889 aa)
	ARB_07560	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (220 aa)
	ARB_00035	Probable mannosyl-oligosaccharide alpha-1,2-mannosidase ARB_00035; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2). (509 aa)
	ARB_00483	TPR_REGION domain-containing protein. (361 aa)
	ARB_00872	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (278 aa)
	ARB_01001	Proteasome component (Ecm29), putative. (1852 aa)
	ARB_01039	AAA domain-containing protein; Belongs to the AAA ATPase family. (393 aa)
	ARB_01040	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (731 aa)
	ARB_01043	UBX domain-containing protein. (523 aa)
	ARB_01448	HECT domain-containing protein. (1209 aa)
	ARB_01577	U-box domain-containing protein. (1067 aa)
	ARB_01581	J domain-containing protein. (374 aa)
	ARB_01583	Uncharacterized protein. (293 aa)
	ARB_01811	UBX domain-containing protein. (526 aa)
	ARB_01910	Uncharacterized protein. (862 aa)
	ARB_02498	OTU domain-containing protein. (333 aa)
	ARB_02902	Hsp40 co-chaperone Jid1, putative. (305 aa)
	ARB_03236	UBIQUITIN_CONJUGAT_2 domain-containing protein. (323 aa)
	ARB_03253	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (586 aa)
	ARB_03311	Uncharacterized protein; Belongs to the AAA ATPase family. (908 aa)

Your Current Organism:

Trichophyton benhamiae

NCBI taxonomy Id: 663331
Other names: Arthroderma benhamiae CBS 112371, T. benhamiae CBS 112371, Trichophyton benhamiae CBS 112371

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARB_00035	ARB_01040	D4AV26	D4AXX1	Probable mannosyl-oligosaccharide alpha-1,2-mannosidase ARB_00035; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.925
ARB_00483	ARB_06765	D4AWB8	D4ARM2	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.890
ARB_00872	ARB_01811	D4AXE4	D4B040	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	UBX domain-containing protein.	0.780
ARB_00872	ARB_01910	D4AXE4	D4B0D6	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.991
ARB_00872	ARB_03236	D4AXE4	D4B447	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.489
ARB_00872	ARB_03311	D4AXE4	D4B4C2	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.986
ARB_00872	ARB_04928	D4AXE4	D4AKT3	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	RING finger membrane protein.	0.616
ARB_00872	ARB_05266	D4AXE4	D4ALR8	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.956
ARB_00872	ARB_06104	D4AXE4	D4APD6	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.497
ARB_00872	ARB_06109	D4AXE4	D4APE1	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	AZUL domain-containing protein.	0.553
ARB_00872	ARB_06440	D4AXE4	D4AQD3	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	RING-type domain-containing protein.	0.997
ARB_00872	ARB_06493	D4AXE4	D4AQI6	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Misfolded glycoproteins degradation protein Yos9, putative.	0.987
ARB_00872	ARB_06748	D4AXE4	D4ARK5	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.628
ARB_00872	ARB_06765	D4AXE4	D4ARM2	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.734
ARB_00872	ARB_07033	D4AXE4	D4AS18	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.970
ARB_00872	ARB_07299	D4AXE4	D4AST4	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	UBX domain protein.	0.902
ARB_00872	ARB_07560	D4AXE4	D4ATJ6	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.994
ARB_01001	ARB_01039	D4AXT2	D4AXX0	Proteasome component (Ecm29), putative.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.840
ARB_01001	ARB_06765	D4AXT2	D4ARM2	Proteasome component (Ecm29), putative.	Uncharacterized protein.	0.550
ARB_01039	ARB_01001	D4AXX0	D4AXT2	AAA domain-containing protein; Belongs to the AAA ATPase family.	Proteasome component (Ecm29), putative.	0.840