(13 nodes) Mitotic DNA replication checkpoint signaling network (Papilio xuthus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RR46_10628	DNA topoisomerase 2-binding protein 1-B. (639 aa)
	RR46_14213	Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2123 aa)
	RR46_13554	Claspin-like. (1352 aa)
	RR46_00016	Uncharacterized protein. (90 aa)
	RR46_00053	Uncharacterized protein. (97 aa)
	RR46_03147	Uncharacterized protein. (742 aa)
	RR46_07118	Checkpoint protein; Belongs to the HUS1 family. (299 aa)
	RR46_02567	Dual specificity mitogen-activated protein kinase kinase dSOR1; Belongs to the protein kinase superfamily. (403 aa)
	RR46_02341	DNA topoisomerase 2-binding protein 1-A. (1342 aa)
	RR46_05055	Serine/threonine-protein kinase grp. (115 aa)
	RR46_05056	Serine/threonine-protein kinase Chk1. (482 aa)
	RR46_04517	Cell cycle checkpoint protein RAD17. (457 aa)
	RR46_13062	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (486 aa)

Your Current Organism:

Papilio xuthus

NCBI taxonomy Id: 66420
Other names: Asian swallowtail, Chinese swallowtail, Chinese yellow swallowtail, P. xuthus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RR46_00016	RR46_00053	A0A0N1IBP1	A0A0N0PFE5	Uncharacterized protein.	Uncharacterized protein.	0.655
RR46_00016	RR46_02341	A0A0N1IBP1	A0A194Q2A0	Uncharacterized protein.	DNA topoisomerase 2-binding protein 1-A.	0.955
RR46_00016	RR46_03147	A0A0N1IBP1	A0A194Q8S8	Uncharacterized protein.	Uncharacterized protein.	0.655
RR46_00016	RR46_04517	A0A0N1IBP1	A0A194PNX6	Uncharacterized protein.	Cell cycle checkpoint protein RAD17.	0.963
RR46_00016	RR46_05055	A0A0N1IBP1	A0A194Q0J0	Uncharacterized protein.	Serine/threonine-protein kinase grp.	0.973
RR46_00016	RR46_05056	A0A0N1IBP1	A0A194PU41	Uncharacterized protein.	Serine/threonine-protein kinase Chk1.	0.973
RR46_00016	RR46_07118	A0A0N1IBP1	A0A194Q4R4	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.938
RR46_00016	RR46_10628	A0A0N1IBP1	A0A194PK19	Uncharacterized protein.	DNA topoisomerase 2-binding protein 1-B.	0.955
RR46_00016	RR46_13062	A0A0N1IBP1	A0A194PKP2	Uncharacterized protein.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.814
RR46_00016	RR46_13554	A0A0N1IBP1	A0A194PH10	Uncharacterized protein.	Claspin-like.	0.813
RR46_00053	RR46_00016	A0A0N0PFE5	A0A0N1IBP1	Uncharacterized protein.	Uncharacterized protein.	0.655
RR46_00053	RR46_14213	A0A0N0PFE5	A0A194PI47	Uncharacterized protein.	Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family.	0.655
RR46_02341	RR46_00016	A0A194Q2A0	A0A0N1IBP1	DNA topoisomerase 2-binding protein 1-A.	Uncharacterized protein.	0.955
RR46_02341	RR46_04517	A0A194Q2A0	A0A194PNX6	DNA topoisomerase 2-binding protein 1-A.	Cell cycle checkpoint protein RAD17.	0.875
RR46_02341	RR46_05055	A0A194Q2A0	A0A194Q0J0	DNA topoisomerase 2-binding protein 1-A.	Serine/threonine-protein kinase grp.	0.803
RR46_02341	RR46_05056	A0A194Q2A0	A0A194PU41	DNA topoisomerase 2-binding protein 1-A.	Serine/threonine-protein kinase Chk1.	0.803
RR46_02341	RR46_07118	A0A194Q2A0	A0A194Q4R4	DNA topoisomerase 2-binding protein 1-A.	Checkpoint protein; Belongs to the HUS1 family.	0.860
RR46_02341	RR46_13062	A0A194Q2A0	A0A194PKP2	DNA topoisomerase 2-binding protein 1-A.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.544
RR46_02341	RR46_13554	A0A194Q2A0	A0A194PH10	DNA topoisomerase 2-binding protein 1-A.	Claspin-like.	0.791
RR46_02341	RR46_14213	A0A194Q2A0	A0A194PI47	DNA topoisomerase 2-binding protein 1-A.	Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family.	0.955