(51 nodes) Regulation of small molecule metabolic process network (Papilio xuthus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RR46_11764	Phosphatidate phosphatase LPIN2. (1006 aa)
	RR46_14571	Glycine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family. (293 aa)
	RR46_14427	Inhibin beta chain. (156 aa)
	RR46_14966	4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (495 aa)
	RR46_15021	Ecdysone-inducible protein E75. (574 aa)
	RR46_08247	Sterol regulatory element-binding protein cleavage-activating protein. (1354 aa)
	RR46_15017	Ecdysone-inducible protein E75. (222 aa)
	RR46_14043	Breast cancer type 1 susceptibility protein-like. (649 aa)
	RR46_14049	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (841 aa)
	RR46_14854	TIG_2 domain-containing protein. (188 aa)
	RR46_04461	Protein phosphatase; Belongs to the PP2C family. (312 aa)
	RR46_08870	Neurogenic locus Notch protein. (576 aa)
	RR46_08806	Myb_DNA-bind_5 domain-containing protein. (273 aa)
	RR46_08871	Neurogenic locus Notch protein. (1725 aa)
	RR46_06831	Tetratricopeptide repeat protein 39B. (685 aa)
	RR46_11307	Serine/threonine-protein kinase ULK2. (692 aa)
	RR46_12321	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (221 aa)
	RR46_12491	Protein-serine/threonine kinase. (408 aa)
	RR46_06827	Tetratricopeptide repeat protein 39A. (421 aa)
	RR46_12652	Mothers against decapentaplegic homolog. (452 aa)
	RR46_12473	DNA-binding protein Ets97D. (463 aa)
	RR46_04912	Protein SCO1-like, mitochondrial. (256 aa)
	RR46_12493	Uncharacterized protein. (70 aa)
	RR46_06779	Uncharacterized protein. (275 aa)
	RR46_12320	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (461 aa)
	RR46_04564	Methyltransferase-like protein 20. (193 aa)
	RR46_10114	Protein FAM173B. (193 aa)
	RR46_10146	Leucine-zipper-like transcriptional regulator 1. (243 aa)
	RR46_05425	Adrenodoxin, mitochondrial. (159 aa)
	RR46_10147	Leucine-zipper-like transcriptional regulator 1. (555 aa)
	RR46_10217	DnaJ-like subfamily C member 30. (218 aa)
	RR46_03823	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
	RR46_09386	[Pyruvate dehydrogenase [lipoamide]] kinase, mitochondrial. (83 aa)
	RR46_02730	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (149 aa)
	RR46_04618	RING finger protein nhl-1. (1171 aa)
	RR46_07190	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
	RR46_03074	Adrenodoxin-like protein, mitochondrial. (166 aa)
	RR46_05549	RING finger protein nhl-1. (1226 aa)
	RR46_05208	Sterol regulatory element-binding protein 1. (1064 aa)
	RR46_07706	Dystroglycan. (1223 aa)
	RR46_03234	Plexin-A4. (1897 aa)
	RR46_03233	Acyl-CoA:lysophosphatidylglycerol acyltransferase 1. (187 aa)
	RR46_01940	Gonadotropin-releasing hormone II receptor; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (436 aa)
	RR46_03231	Acyl-CoA:lysophosphatidylglycerol acyltransferase 1. (213 aa)
	RR46_03966	WD and tetratricopeptide repeats protein 1. (289 aa)
	RR46_06347	Serine protease; Belongs to the peptidase S1B family. (528 aa)
	RR46_06552	Frataxin-like, mitochondrial. (180 aa)
	RR46_02235	RING finger protein nhl-1. (629 aa)
	RR46_03967	WD and tetratricopeptide repeats protein 1. (474 aa)
	RR46_07810	Gonadotropin-releasing hormone II receptor; Belongs to the G-protein coupled receptor 1 family. (396 aa)
	RR46_08141	Guanine nucleotide-binding protein subunit beta-like protein. (319 aa)

Your Current Organism:

Papilio xuthus

NCBI taxonomy Id: 66420
Other names: Asian swallowtail, Chinese swallowtail, Chinese yellow swallowtail, P. xuthus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RR46_01940	RR46_07810	A0A194QHQ9	A0A194QKR9	Gonadotropin-releasing hormone II receptor; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	Gonadotropin-releasing hormone II receptor; Belongs to the G-protein coupled receptor 1 family.	0.707
RR46_02235	RR46_12652	A0A194QJG6	A0A194PTI1	RING finger protein nhl-1.	Mothers against decapentaplegic homolog.	0.537
RR46_02730	RR46_03234	A0A194Q474	A0A194QGG0	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Plexin-A4.	0.419
RR46_02730	RR46_07706	A0A194Q474	A0A194QEP1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Dystroglycan.	0.614
RR46_02730	RR46_14854	A0A194Q474	A0A194PJT1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	TIG_2 domain-containing protein.	0.419
RR46_02730	RR46_15017	A0A194Q474	A0A194PER5	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Ecdysone-inducible protein E75.	0.450
RR46_02730	RR46_15021	A0A194Q474	A0A194PE27	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Ecdysone-inducible protein E75.	0.450
RR46_03074	RR46_05425	A0A194Q6P2	A0A194Q112	Adrenodoxin-like protein, mitochondrial.	Adrenodoxin, mitochondrial.	0.560
RR46_03074	RR46_06552	A0A194Q6P2	A0A194QIW6	Adrenodoxin-like protein, mitochondrial.	Frataxin-like, mitochondrial.	0.828
RR46_03231	RR46_03823	A0A194QI64	A0A194Q296	Acyl-CoA:lysophosphatidylglycerol acyltransferase 1.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.469
RR46_03231	RR46_07190	A0A194QI64	A0A194Q6G9	Acyl-CoA:lysophosphatidylglycerol acyltransferase 1.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.469
RR46_03231	RR46_11764	A0A194QI64	A0A194PUE7	Acyl-CoA:lysophosphatidylglycerol acyltransferase 1.	Phosphatidate phosphatase LPIN2.	0.633
RR46_03233	RR46_03823	A0A194QGJ5	A0A194Q296	Acyl-CoA:lysophosphatidylglycerol acyltransferase 1.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.469
RR46_03233	RR46_07190	A0A194QGJ5	A0A194Q6G9	Acyl-CoA:lysophosphatidylglycerol acyltransferase 1.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.469
RR46_03233	RR46_11764	A0A194QGJ5	A0A194PUE7	Acyl-CoA:lysophosphatidylglycerol acyltransferase 1.	Phosphatidate phosphatase LPIN2.	0.633
RR46_03234	RR46_02730	A0A194QGG0	A0A194Q474	Plexin-A4.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.419
RR46_03234	RR46_03823	A0A194QGG0	A0A194Q296	Plexin-A4.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.429
RR46_03234	RR46_07190	A0A194QGG0	A0A194Q6G9	Plexin-A4.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.409
RR46_03823	RR46_03231	A0A194Q296	A0A194QI64	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Acyl-CoA:lysophosphatidylglycerol acyltransferase 1.	0.469
RR46_03823	RR46_03233	A0A194Q296	A0A194QGJ5	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Acyl-CoA:lysophosphatidylglycerol acyltransferase 1.	0.469