(56 nodes) FCERI mediated NF-kB activation network (Papilio xuthus)

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	RR46_06027	Putative nuclease HARBI1. (360 aa)
	RR46_14430	Inhibitor of nuclear factor kappa-B kinase subunit beta. (773 aa)
	RR46_14435	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (1000 aa)
	RR46_13473	26S protease regulatory subunit 4; Belongs to the AAA ATPase family. (462 aa)
	RR46_13749	26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (415 aa)
	RR46_13775	Proteasome subunit beta. (205 aa)
	RR46_12836	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (389 aa)
	RR46_12837	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (459 aa)
	RR46_10833	Proteasome subunit beta type-6. (225 aa)
	RR46_13301	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (428 aa)
	RR46_13154	26S proteasome non-ATPase regulatory subunit 7. (327 aa)
	RR46_13796	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (255 aa)
	RR46_11910	Putative nuclease HARBI1. (388 aa)
	RR46_11334	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes. Belongs to the WD repeat LIS1/nudF family. (375 aa)
	RR46_11312	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (925 aa)
	RR46_12362	26S proteasome non-ATPase regulatory subunit 13. (385 aa)
	RR46_12599	Cullin-1. (58 aa)
	RR46_05013	NF-kappa-B inhibitor cactus. (336 aa)
	RR46_12094	Proteasome inhibitor PI31 subunit. (282 aa)
	RR46_07433	Proteasome activator complex subunit 3. (246 aa)
	RR46_02408	Mucosa-associated lymphoid tissue lymphoma translocation protein 1. (352 aa)
	RR46_09449	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (295 aa)
	RR46_12585	Proteasome subunit beta; Belongs to the peptidase T1B family. (262 aa)
	RR46_12600	Cullin-1; Belongs to the cullin family. (720 aa)
	RR46_05470	F-box/WD repeat-containing protein 11. (568 aa)
	RR46_02415	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (269 aa)
	RR46_04793	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (603 aa)
	RR46_07556	Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (245 aa)
	RR46_07566	26S proteasome non-ATPase regulatory subunit 9. (294 aa)
	RR46_02708	Proteasome subunit beta. (205 aa)
	RR46_08066	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (234 aa)
	RR46_09825	26S proteasome non-ATPase regulatory subunit 4. (367 aa)
	RR46_10002	26S proteasome non-ATPase regulatory subunit 12. (442 aa)
	RR46_06256	Proteasome subunit beta. (233 aa)
	RR46_06188	UPF0459 protein CG10681. (222 aa)
	RR46_03469	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (246 aa)
	RR46_05609	26S proteasome non-ATPase regulatory subunit 14. (311 aa)
	RR46_03221	26S proteasome non-ATPase regulatory subunit rpn12. (268 aa)
	RR46_08129	26S protease regulatory subunit rpt1; Belongs to the AAA ATPase family. (434 aa)
	RR46_14098	Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	RR46_12943	26S proteasome non-ATPase regulatory subunit rpn7. (382 aa)
	RR46_14742	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (162 aa)
	RR46_05949	Proteasome subunit beta. (281 aa)
	RR46_13910	Ubiquitin-60S ribosomal protein L40. (129 aa)
	RR46_02122	Embryonic polarity protein dorsal. (512 aa)
	RR46_12934	Putative 26S proteasome non-ATPase regulatory subunit 3. (495 aa)
	RR46_00619	26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (402 aa)
	RR46_06134	26S proteasome non-ATPase regulatory subunit 11. (420 aa)
	RR46_05907	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (249 aa)
	RR46_02241	Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (474 aa)
	RR46_04328	26S proteasome non-ATPase regulatory subunit 5. (736 aa)
	RR46_02260	Ubiquitin-conjugating enzyme E2 R2; Belongs to the ubiquitin-conjugating enzyme family. (242 aa)
	RR46_02134	Embryonic polarity protein dorsal. (788 aa)
	RR46_06189	Ubiquitin-conjugating enzyme E2 T. (119 aa)
	RR46_02773	Nuclear factor NF-kappa-B p110 subunit. (939 aa)
	RR46_07934	Proteasome subunit beta. (283 aa)

Your Current Organism:

Papilio xuthus

NCBI taxonomy Id: 66420
Other names: Asian swallowtail, Chinese swallowtail, Chinese yellow swallowtail, P. xuthus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RR46_00619	RR46_02122	I4DJY4	A0A194QPU0	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	Embryonic polarity protein dorsal.	0.586
RR46_00619	RR46_02134	I4DJY4	A0A194QIY4	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	Embryonic polarity protein dorsal.	0.586
RR46_00619	RR46_02241	I4DJY4	A0A194QK15	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	Proteasome endopeptidase complex; Belongs to the peptidase T1A family.	0.999
RR46_00619	RR46_02415	I4DJY4	A0A194Q2V7	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	0.999
RR46_00619	RR46_02708	I4DJY4	A0A194Q5N8	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	Proteasome subunit beta.	0.992
RR46_00619	RR46_02773	I4DJY4	A0A194QHC6	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	Nuclear factor NF-kappa-B p110 subunit.	0.593
RR46_00619	RR46_03221	I4DJY4	I4DKA5	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit rpn12.	0.998
RR46_00619	RR46_03469	I4DJY4	I4DKX7	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	0.999
RR46_00619	RR46_04328	I4DJY4	A0A194QJT6	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit 5.	0.993
RR46_00619	RR46_05013	I4DJY4	A0A194PV73	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	NF-kappa-B inhibitor cactus.	0.593
RR46_00619	RR46_05609	I4DJY4	I4DKB2	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit 14.	0.999
RR46_00619	RR46_05907	I4DJY4	I4DJQ9	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	0.990
RR46_00619	RR46_05949	I4DJY4	I4DJA3	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	Proteasome subunit beta.	0.999
RR46_00619	RR46_06134	I4DJY4	I4DJY3	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit 11.	0.999
RR46_00619	RR46_06189	I4DJY4	A0A194QHU9	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	Ubiquitin-conjugating enzyme E2 T.	0.674
RR46_00619	RR46_06256	I4DJY4	A0A194QC19	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	Proteasome subunit beta.	0.998
RR46_00619	RR46_07433	I4DJY4	A0A194PWD2	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	Proteasome activator complex subunit 3.	0.821
RR46_00619	RR46_07556	I4DJY4	A0A194Q593	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	Proteasome endopeptidase complex; Belongs to the peptidase T1A family.	0.990
RR46_00619	RR46_07566	I4DJY4	A0A194Q5A2	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit 9.	0.989
RR46_00619	RR46_07934	I4DJY4	A0A194QGW1	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	Proteasome subunit beta.	0.999