(106 nodes) FoxO signaling pathway network (Papilio xuthus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RR46_00379	Mothers against decapentaplegic-like 4. (910 aa)
	RR46_01305	S-phase kinase-associated protein 2. (466 aa)
	RR46_00529	CCHC-type domain-containing protein. (364 aa)
	RR46_00049	Uncharacterized protein. (69 aa)
	RR46_00050	Mitogen-activated protein kinase 14A. (87 aa)
	RR46_00217	Uncharacterized protein. (409 aa)
	RR46_01598	Homer protein-like 2. (301 aa)
	RR46_01306	BNIP3-like. (165 aa)
	RR46_01011	Non-specific serine/threonine protein kinase. (797 aa)
	RR46_00216	Glucose-6-phosphatase 3. (181 aa)
	RR46_01600	Homer protein-like 2. (177 aa)
	RR46_01682	Forkhead box protein O. (167 aa)
	RR46_00625	Homer protein-like 2. (132 aa)
	RR46_01010	Ribosomal protein S6 kinase alpha-5. (507 aa)
	RR46_01683	Forkhead box protein O. (497 aa)
	RR46_14430	Inhibitor of nuclear factor kappa-B kinase subunit beta. (773 aa)
	RR46_14617	CREB-binding protein. (2110 aa)
	RR46_08268	5'-AMP-activated protein kinase subunit gamma-2. (396 aa)
	RR46_08269	Uncharacterized protein. (383 aa)
	RR46_13432	Titin. (1431 aa)
	RR46_08270	Uncharacterized protein. (571 aa)
	RR46_13967	Phosphatidylinositol 3-kinase regulatory subunit gamma. (436 aa)
	RR46_14037	5'-AMP-activated protein kinase subunit beta-1. (313 aa)
	RR46_13530	Testis-specific serine/threonine-protein kinase 2; Belongs to the protein kinase superfamily. (346 aa)
	RR46_14584	Bombyxin A-2-like. (200 aa)
	RR46_14614	Histone acetyltransferase p300. (305 aa)
	RR46_12921	5'-AMP-activated protein kinase subunit gamma-2. (684 aa)
	RR46_15009	Serine/threonine-protein kinase PLK4. (679 aa)
	RR46_10768	Serine/threonine-protein kinase polo. (565 aa)
	RR46_12964	Non-specific serine/threonine protein kinase. (2351 aa)
	RR46_13243	Catalase. (560 aa)
	RR46_05844	Protein arginine N-methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (518 aa)
	RR46_11800	G2/mitotic-specific cyclin-B; Belongs to the cyclin family. (486 aa)
	RR46_06650	RING finger protein 165. (975 aa)
	RR46_06720	Mothers against decapentaplegic homolog. (747 aa)
	RR46_12011	Tyrosine-protein kinase receptor. (1338 aa)
	RR46_12061	Mitogen-activated protein kinase. (365 aa)
	RR46_08805	Raf-like serine/threonine-protein kinase phl. (745 aa)
	RR46_12261	Catalase. (673 aa)
	RR46_11504	Ras-related protein Ral-a. (242 aa)
	RR46_08723	Protein arginine N-methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (353 aa)
	RR46_06795	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (507 aa)
	RR46_06815	Ras-GEF domain-containing family member 1B. (380 aa)
	RR46_12386	Protein son of sevenless. (1476 aa)
	RR46_12652	Mothers against decapentaplegic homolog. (452 aa)
	RR46_06918	Receptor protein-tyrosine kinase. (1297 aa)
	RR46_12508	Glucose-6-phosphatase. (361 aa)
	RR46_09353	Uncharacterized protein. (93 aa)
	RR46_09095	GTP-binding protein RAD. (213 aa)
	RR46_09096	Uncharacterized protein. (155 aa)
	RR46_10932	Serine/threonine-protein kinase 11; Belongs to the protein kinase superfamily. (489 aa)
	RR46_09351	3-phosphoinositide-dependent protein kinase 1. (535 aa)
	RR46_06814	Ras-GEF domain-containing family member 1B-B. (186 aa)
	RR46_09439	Cyclin-dependent kinase inhibitor 1B. (143 aa)
	RR46_04630	Bombyxin A-4. (69 aa)
	RR46_09247	Uncharacterized protein. (218 aa)
	RR46_03936	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (227 aa)
	RR46_02331	Uncharacterized protein. (192 aa)
	RR46_02611	Myosin-IXa. (689 aa)
	RR46_02610	Myosin-IXa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1318 aa)
	RR46_04725	Insulin receptor substrate 1. (138 aa)
	RR46_02567	Dual specificity mitogen-activated protein kinase kinase dSOR1; Belongs to the protein kinase superfamily. (403 aa)
	RR46_04723	Uncharacterized protein. (508 aa)
	RR46_02881	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1053 aa)
	RR46_04738	annotation not available (423 aa)
	RR46_07107	Cyclin-G2. (383 aa)
	RR46_04563	Growth arrest and DNA damage-inducible protein GADD45 beta. (165 aa)
	RR46_04628	Bombyxin A-1-like. (91 aa)
	RR46_07651	Phosphoenolpyruvate carboxykinase [GTP]. (638 aa)
	RR46_07528	GTP-binding protein REM 1. (546 aa)
	RR46_07190	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
	RR46_05524	Forkhead box protein J3. (305 aa)
	RR46_08641	Catalase. (518 aa)
	RR46_05062	Testis-specific serine/threonine-protein kinase 1; Belongs to the protein kinase superfamily. (361 aa)
	RR46_04724	Insulin receptor substrate 1. (221 aa)
	RR46_05063	Testis-specific serine/threonine-protein kinase 1. (683 aa)
	RR46_05186	G1/S-specific cyclin-D2; Belongs to the cyclin family. (297 aa)
	RR46_03408	F-box only protein 25. (307 aa)
	RR46_03409	Uncharacterized protein. (90 aa)
	RR46_08161	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (194 aa)
	RR46_05174	Ras-related and estrogen-regulated growth inhibitor. (316 aa)
	RR46_09926	Ubiquitin carboxyl-terminal hydrolase. (528 aa)
	RR46_09986	Casein kinase I isoform epsilon; Belongs to the protein kinase superfamily. (340 aa)
	RR46_09935	Protein E(Sev)2B. (211 aa)
	RR46_09693	Mitogen-activated protein kinase. (438 aa)
	RR46_06165	Lipase 3. (1020 aa)
	RR46_06471	Testis-specific serine/threonine-protein kinase 4; Belongs to the protein kinase superfamily. (344 aa)
	RR46_01943	Ras-like protein 1. (125 aa)
	RR46_03224	Insulin receptor. (855 aa)
	RR46_03284	RAC serine/threonine-protein kinase. (316 aa)
	RR46_03283	RAC-alpha serine/threonine-protein kinase. (147 aa)
	RR46_03285	RAC serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (372 aa)
	RR46_09929	Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (1124 aa)
	RR46_02451	G2/mitotic-specific cyclin-B3; Belongs to the cyclin family. (518 aa)
	RR46_04173	Serine/threonine-protein kinase NLK. (301 aa)
	RR46_04175	Serine/threonine kinase NLK. (102 aa)
	RR46_04185	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
	RR46_03286	RAC serine/threonine-protein kinase. (192 aa)
	RR46_02144	Fork head domain transcription factor slp2. (252 aa)
	RR46_02145	Fork head domain transcription factor slp2. (316 aa)
	RR46_03952	E3 ubiquitin-protein ligase Mdm2. (407 aa)
	RR46_04303	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (127 aa)
	RR46_07820	SNARE-associated protein Snapin. (146 aa)
	RR46_01936	Ras-specific guanine nucleotide-releasing factor 1. (1365 aa)
	RR46_01976	Non-specific serine/threonine protein kinase. (522 aa)
	RR46_09281	Gamma-aminobutyric acid receptor-associated protein. (117 aa)

Your Current Organism:

Papilio xuthus

NCBI taxonomy Id: 66420
Other names: Asian swallowtail, Chinese swallowtail, Chinese yellow swallowtail, P. xuthus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RR46_00049	RR46_00050	A0A0N0PEX3	A0A0N0PF84	Uncharacterized protein.	Mitogen-activated protein kinase 14A.	0.584
RR46_00049	RR46_01682	A0A0N0PEX3	A0A0N1IN67	Uncharacterized protein.	Forkhead box protein O.	0.401
RR46_00049	RR46_01683	A0A0N0PEX3	A0A0N1PGI7	Uncharacterized protein.	Forkhead box protein O.	0.401
RR46_00049	RR46_02144	A0A0N0PEX3	A0A194QIZ4	Uncharacterized protein.	Fork head domain transcription factor slp2.	0.401
RR46_00049	RR46_02145	A0A0N0PEX3	A0A194QJG3	Uncharacterized protein.	Fork head domain transcription factor slp2.	0.401
RR46_00049	RR46_03936	A0A0N0PEX3	A0A194Q203	Uncharacterized protein.	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.	0.893
RR46_00049	RR46_03952	A0A0N0PEX3	A0A194QJM5	Uncharacterized protein.	E3 ubiquitin-protein ligase Mdm2.	0.670
RR46_00049	RR46_04185	A0A0N0PEX3	A0A194QI47	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.502
RR46_00049	RR46_04563	A0A0N0PEX3	A0A194Q5C0	Uncharacterized protein.	Growth arrest and DNA damage-inducible protein GADD45 beta.	0.618
RR46_00049	RR46_04738	A0A0N0PEX3	A0A194Q425	Uncharacterized protein.	annotation not available	0.401
RR46_00049	RR46_05524	A0A0N0PEX3	A0A194Q7F9	Uncharacterized protein.	Forkhead box protein J3.	0.401
RR46_00049	RR46_09439	A0A0N0PEX3	A0A194PYW3	Uncharacterized protein.	Cyclin-dependent kinase inhibitor 1B.	0.466
RR46_00049	RR46_10768	A0A0N0PEX3	A0A194PKH7	Uncharacterized protein.	Serine/threonine-protein kinase polo.	0.857
RR46_00049	RR46_12061	A0A0N0PEX3	A0A194PP20	Uncharacterized protein.	Mitogen-activated protein kinase.	0.584
RR46_00049	RR46_14614	A0A0N0PEX3	A0A194PJ49	Uncharacterized protein.	Histone acetyltransferase p300.	0.453
RR46_00049	RR46_14617	A0A0N0PEX3	A0A194PDM4	Uncharacterized protein.	CREB-binding protein.	0.453
RR46_00049	RR46_15009	A0A0N0PEX3	A0A194PK82	Uncharacterized protein.	Serine/threonine-protein kinase PLK4.	0.857
RR46_00050	RR46_00049	A0A0N0PF84	A0A0N0PEX3	Mitogen-activated protein kinase 14A.	Uncharacterized protein.	0.584
RR46_00050	RR46_00217	A0A0N0PF84	A0A0N0PFD3	Mitogen-activated protein kinase 14A.	Uncharacterized protein.	0.551
RR46_00050	RR46_00379	A0A0N0PF84	A0A0N0P9E4	Mitogen-activated protein kinase 14A.	Mothers against decapentaplegic-like 4.	0.630