(6 nodes) Regulation of nitrogen utilization, and Bacterial regulatory protein, Fis family network (Erwinia amylovora)

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Your Input:
	glnG	Transcriptional regulatory protein glnG; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (469 aa)
	glnL	Histidine protein kinase sensor for GlnG regulator (nitrogen regulator II, NRII), Two-component nitrogen regulation protein. (349 aa)
	glnK	Nitrogen regulatory PII-like, alpha/beta; Belongs to the P(II) protein family. (112 aa)
	amtB	Ammonium transporter, TC 1.A.11.1.1 Ammonia channel. (433 aa)
	glnB	Nitrogen regulatory protein PII/ATP; Belongs to the P(II) protein family. (112 aa)
	glnD	protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. (885 aa)

Your Current Organism:

Erwinia amylovora

NCBI taxonomy Id: 665029
Other names: E. amylovora CFBP1430, Erwinia amylovora CFBP1430, Erwinia amylovora str. CFBP1430, Erwinia amylovora strain CFBP1430

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
amtB	glnB	EAMY_0996	EAMY_2606	Ammonium transporter, TC 1.A.11.1.1 Ammonia channel.	Nitrogen regulatory protein PII/ATP; Belongs to the P(II) protein family.	0.997
amtB	glnD	EAMY_0996	EAMY_2762	Ammonium transporter, TC 1.A.11.1.1 Ammonia channel.	protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.	0.449
amtB	glnK	EAMY_0996	EAMY_0995	Ammonium transporter, TC 1.A.11.1.1 Ammonia channel.	Nitrogen regulatory PII-like, alpha/beta; Belongs to the P(II) protein family.	0.999
amtB	glnL	EAMY_0996	EAMY_0035	Ammonium transporter, TC 1.A.11.1.1 Ammonia channel.	Histidine protein kinase sensor for GlnG regulator (nitrogen regulator II, NRII), Two-component nitrogen regulation protein.	0.802
glnB	amtB	EAMY_2606	EAMY_0996	Nitrogen regulatory protein PII/ATP; Belongs to the P(II) protein family.	Ammonium transporter, TC 1.A.11.1.1 Ammonia channel.	0.997
glnB	glnD	EAMY_2606	EAMY_2762	Nitrogen regulatory protein PII/ATP; Belongs to the P(II) protein family.	protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.	0.977
glnB	glnG	EAMY_2606	EAMY_0034	Nitrogen regulatory protein PII/ATP; Belongs to the P(II) protein family.	Transcriptional regulatory protein glnG; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.	0.741
glnB	glnK	EAMY_2606	EAMY_0995	Nitrogen regulatory protein PII/ATP; Belongs to the P(II) protein family.	Nitrogen regulatory PII-like, alpha/beta; Belongs to the P(II) protein family.	0.764
glnB	glnL	EAMY_2606	EAMY_0035	Nitrogen regulatory protein PII/ATP; Belongs to the P(II) protein family.	Histidine protein kinase sensor for GlnG regulator (nitrogen regulator II, NRII), Two-component nitrogen regulation protein.	0.991
glnD	amtB	EAMY_2762	EAMY_0996	protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.	Ammonium transporter, TC 1.A.11.1.1 Ammonia channel.	0.449
glnD	glnB	EAMY_2762	EAMY_2606	protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.	Nitrogen regulatory protein PII/ATP; Belongs to the P(II) protein family.	0.977
glnD	glnK	EAMY_2762	EAMY_0995	protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.	Nitrogen regulatory PII-like, alpha/beta; Belongs to the P(II) protein family.	0.791
glnD	glnL	EAMY_2762	EAMY_0035	protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.	Histidine protein kinase sensor for GlnG regulator (nitrogen regulator II, NRII), Two-component nitrogen regulation protein.	0.608
glnG	glnB	EAMY_0034	EAMY_2606	Transcriptional regulatory protein glnG; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.	Nitrogen regulatory protein PII/ATP; Belongs to the P(II) protein family.	0.741
glnG	glnL	EAMY_0034	EAMY_0035	Transcriptional regulatory protein glnG; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.	Histidine protein kinase sensor for GlnG regulator (nitrogen regulator II, NRII), Two-component nitrogen regulation protein.	0.999
glnK	amtB	EAMY_0995	EAMY_0996	Nitrogen regulatory PII-like, alpha/beta; Belongs to the P(II) protein family.	Ammonium transporter, TC 1.A.11.1.1 Ammonia channel.	0.999
glnK	glnB	EAMY_0995	EAMY_2606	Nitrogen regulatory PII-like, alpha/beta; Belongs to the P(II) protein family.	Nitrogen regulatory protein PII/ATP; Belongs to the P(II) protein family.	0.764
glnK	glnD	EAMY_0995	EAMY_2762	Nitrogen regulatory PII-like, alpha/beta; Belongs to the P(II) protein family.	protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.	0.791
glnK	glnL	EAMY_0995	EAMY_0035	Nitrogen regulatory PII-like, alpha/beta; Belongs to the P(II) protein family.	Histidine protein kinase sensor for GlnG regulator (nitrogen regulator II, NRII), Two-component nitrogen regulation protein.	0.801
glnL	amtB	EAMY_0035	EAMY_0996	Histidine protein kinase sensor for GlnG regulator (nitrogen regulator II, NRII), Two-component nitrogen regulation protein.	Ammonium transporter, TC 1.A.11.1.1 Ammonia channel.	0.802