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cysE cysE sbp sbp metB metB metE metE cysI1 cysI1 nlpA nlpA metC metC metK metK EAMY_0622 EAMY_0622 cysJ cysJ cysI3 cysI3 cysH cysH cysD cysD cysN cysN cysC cysC yxjG yxjG cysS cysS ssuB ssuB ssuC ssuC ssuD ssuD ssuA ssuA ssuE ssuE EAMY_1798 EAMY_1798 EAMY_1799 EAMY_1799 EAMY_1800 EAMY_1800 EAMY_1801 EAMY_1801 EAMY_1802 EAMY_1802 msuD msuD EAMY_1804 EAMY_1804 yciW yciW yebR yebR patB patB cysK cysK cysM cysM cysA cysA cysW cysW cysU cysU cysP cysP sseA sseA metN metN metI metI metQ metQ EAMY_2734 EAMY_2734 mdeA3 mdeA3 tauD1 tauD1 cysQ cysQ metA metA tauD3 tauD3 tauC tauC tauB tauB tauA tauA EAMY_3408 EAMY_3408 yheT yheT yheU yheU prkB prkB glpE glpE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cysESerine O-acetyltransferase. (272 aa)
sbpSulphate-binding protein, TC 3.A.1.6.1 Sulfate-binding protein. (329 aa)
metBCystathionine gamma-synthase (CGS) (O-succinylhomoserine (thiol)-lyase), PLP-dependent enzyme. (386 aa)
metE5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (757 aa)
cysI1Sulfite reductase (NADPH) flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. (585 aa)
nlpAD-methionine-binding lipoprotein metQ precursor; Lipoprotein YaeC, NLPA lipoprotein, TIGR00363: lipoprotein, YaeC family; Belongs to the nlpA lipoprotein family. (267 aa)
metCCystathionine gamma-lyase (Gamma-cystathionase), Pyridoxal phosphate-dependent transferase. (397 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (384 aa)
EAMY_0622Putative acyltransferase; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. (143 aa)
cysJSulfite reductase (NADPH) flavoprotein beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the N-terminal section; belongs to the flavodoxin family. (600 aa)
cysI3Sulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (571 aa)
cysH3'-phosphoadenosine 5'-phosphosulfate (PAPS) reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (243 aa)
cysDSulfate adenylyltransferase subunit 2 (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase small subunit), Sulphate adenylyltransferase, small subunit, Phosphoadenosine phosphosulfate reductase family. (302 aa)
cysNATP-sulfurylase (ATP:sulfate adenylyltransferase), subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (476 aa)
cysCAdenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. (222 aa)
yxjG5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase (Methionine synthase, vitamin-B12 independent isozyme) (Cobalamin-independent methionine synthase), Methionine synthase, vitamin-B12 independent. (366 aa)
cysSCysteinyl-tRNA synthetase (Cysteine-tRNA ligase) (CysRS); Belongs to the class-I aminoacyl-tRNA synthetase family. (502 aa)
ssuBAliphatic sulfonate ABC transporter, ATP-binding protein; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system. (262 aa)
ssuCAliphatic sulfonate ABC transporter, permease protein; Binding-protein-dependent transport systems inner membrane component, TC 3.A.1.17.2 ABC transporter membrane subunit precursor. (263 aa)
ssuDAlkanesulfonate monooxygenase; Catalyzes the desulfonation of aliphatic sulfonates. Belongs to the SsuD family. (381 aa)
ssuAAliphatic sulfonate ABC transporter, substrate-binding protein precursor, TC 3.A.1.17.2 putative sulfonate binding protein precursor. (319 aa)
ssuENADPH-dependent FMN reductase. (183 aa)
EAMY_1798acyl-CoA dehydrogenase family protein. (401 aa)
EAMY_1799Putative sugar transport protein; Major facilitator superfamily. (107 aa)
EAMY_1800Hypothetical protein; Bacterial luciferase-like. (463 aa)
EAMY_1801Hypothetical protein; FAD dependent oxidoreductase. (469 aa)
EAMY_1802Alkanesulfonate monooxygenase (FMNH2-dependent aliphatic sulfonate monooxygenase), Bacterial luciferase-like. (362 aa)
msuDAlkanesulfonate monooxygenase; Catalyzes the desulfonation of aliphatic sulfonates. Belongs to the SsuD family. (390 aa)
EAMY_1804Nif-specific regulatory protein; ABC transporter, substrate-binding protein, aliphatic sulphonates, Sigma-54 interaction domain, phageshock_pspF: psp operon transcriptional activator PspF. (629 aa)
yciWUncharacterized protein conserved in bacteria. (379 aa)
yebRUPF0067 protein yebR; GAF. (166 aa)
patBAspartate aminotransferase (Transaminase A) (ASPAT), Pyridoxal phosphate-dependent transferase, major region, Aminotransferase class I and II. (379 aa)
cysKCysteine synthase A, O-acetylserine sulfhydrolase A subunit, Pyridoxal-phosphate dependent enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family. (323 aa)
cysMCysteine synthase B (O-acetylserine sulfhydrylase B) (O-acetylserine (Thiol)-lyase B) (CSase B), Pyridoxal-phosphate dependent enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family. (295 aa)
cysASulfate ABC transport system, ATP-binding component; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (362 aa)
cysWSulphate ABC transporter permease protein 2, Binding-protein-dependent transport system inner membrane component, TC 3.A.1.6.1 Sulfate transport system permease protein cysW. (291 aa)
cysUSulfate ABC transport system, permease protein cysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (277 aa)
cysPThiosulphate-binding protein, TC 3.A.1.6.1 Thiosulfate-binding protein precursor. (338 aa)
sseAThiosulfate sulfurtransferase (Rhodanese), Rhodanese-like, Rhodanese-like domain. (286 aa)
metNMethionine ABC transport system, ATP-binding component; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (373 aa)
metIBinding-protein-dependent transport systems inner membrane component, TC 3.A.1.24.1 D-methionine transport system permease protein MetI. (217 aa)
metQD-methionine transport system, periplasmic component, TC 3.A.1.24.1 D-methionine-binding lipoprotein MetQ precursor; Belongs to the nlpA lipoprotein family. (271 aa)
EAMY_2734Hypothetical protein. (340 aa)
mdeA3Cystathionine gamma-lyase (Gamma-cystathionase), Pyridoxal phosphate-dependent transferase, major region, Cys/Met metabolism PLP-dependent enzyme, met_gam_lyase: methionine gamma-lyase. (426 aa)
tauD1Uncharacterized dioxygenase Rv3406/MT3514, Taurine catabolism dioxygenase TauD/TfdA, Taurine catabolism dioxygenase TauD, TfdA family. (256 aa)
cysQInositol-1-monophosphatase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (246 aa)
metAHomoserine transsuccinylase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. (309 aa)
tauD3Taurine dioxygenase, 2-oxoglutarate-dependent; Alpha-ketoglutarate-dependent taurine dioxygenase (2-aminoethanesulfonate dioxygenase) (Sulfate starvation-induced protein 3) (SSI3). (279 aa)
tauCTaurine transport permease protein tauC; Binding-protein-dependent transport systems inner membrane component, TC 3.A.1.17.1 Taurine transport system permease protein tauC. (275 aa)
tauBTaurine ABC transporter, ATP-binding protein TauB; Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family. (255 aa)
tauATaurine-binding periplasmic protein precursor (Sulfate starvation-induced protein 1) (SSI1), TC 3.A.1.17.1 Taurine-binding periplasmic protein precursor (Sulfate starvation-induced protein 1) (SSI1). (325 aa)
EAMY_3408Putative transporter, TC 2.A.76.1.-The Resistance to Homoserine/Threonine (RhtB) Family. (200 aa)
yheTAbhydrolase domain-containing protein 1 (Lung alpha/beta hydrolase 1), AB-hydrolase YheT, putative. (332 aa)
yheUProtein of unknown function UPF0270, Uncharacterised protein family (UPF0270); Belongs to the UPF0270 family. (81 aa)
prkBPhosphoribulokinase 2 (Phosphopentokinase 2) (PRKase 2) (PRK II). (289 aa)
glpEProtein of glp regulon; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide. (122 aa)
Your Current Organism:
Erwinia amylovora
NCBI taxonomy Id: 665029
Other names: E. amylovora CFBP1430, Erwinia amylovora CFBP1430, Erwinia amylovora str. CFBP1430, Erwinia amylovora strain CFBP1430
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