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atpI atpI atpB atpB atpE atpE atpF atpF atpH atpH atpA atpA atpG atpG atpD atpD atpC atpC EAMY_3625 EAMY_3625 prtF prtF kdpA kdpA kdpB kdpB kdpC kdpC dcrB dcrB ugpB ugpB ugpA ugpA ugpE ugpE ugpC ugpC yheR yheR kefB kefB ymcB ymcB yqjC yqjC EAMY_3096 EAMY_3096 EAMY_2833 EAMY_2833 folK folK EAMY_2783 EAMY_2783 fhuB fhuB metI metI metN metN proX proX proW proW proV proV tsx tsx yfhL yfhL EAMY_2521 EAMY_2521 cysU cysU cysW cysW cysA cysA EAMY_2393 EAMY_2393 potA potA nuoA nuoA nuoCD nuoCD nuoF nuoF nuoG nuoG nuoJ nuoJ nuoL nuoL ompC ompC yegM yegM amsH amsH rfbB1 rfbB1 EAMY_2188 EAMY_2188 yiuA3 yiuA3 sitD sitD sitC sitC sitB sitB EAMY_2140 EAMY_2140 efeU efeU ycdO ycdO znuB znuB znuC znuC EAMY_1768 EAMY_1768 ompF ompF scrY scrY ycfW ycfW ycfV ycfV ycfU ycfU ndh ndh ompA ompA ompN ompN cydD cydD cydC cydC potH potH potG potG modF modF sdhB sdhB sdhA sdhA sdhC sdhC ybeC ybeC acrA acrA cyoC cyoC cyoD cyoD omp39 omp39 mdtA mdtA yiuA1 yiuA1 exbD exbD tolC tolC ompU ompU ampH1 ampH1 yjgP yjgP yhbG yhbG tatC tatC tatB tatB tatA tatA argH argH
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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atpIATPase, F0 complex, subunit I, proteobacteria-type, ATP synthase I chain. (126 aa)
atpBATP synthase A chain; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (272 aa)
atpEATP synthase C chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (80 aa)
atpFATP synthase subunit B protein; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (156 aa)
atpHMembrane-bound ATP synthase, F1 sector, delta-subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (177 aa)
atpAATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (513 aa)
atpGMembrane-bound ATP synthase, F1 sector, gamma-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (289 aa)
atpDMembrane-bound ATP synthase, F1 sector, beta-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (460 aa)
atpCMembrane-bound ATP synthase, F1 sector, epsilon-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (139 aa)
EAMY_3625Hypothetical protein predicted by Glimmer/Critica. (404 aa)
prtFType I secretion outer membrane protein, TolC, Outer membrane efflux protein, TC 1.B.17.1.2 proteases secretion protein PrtF precursor. (443 aa)
kdpAPotassium-transporting ATPase A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (561 aa)
kdpBPotassium-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (682 aa)
kdpCP-type ATPase, high-affinity potassium transport system, C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (190 aa)
dcrBProtein dcrB precursor. (184 aa)
ugpBSn-glycerol-3-phosphate ABC transport system, periplasmic component ugpB; Bacterial extracellular solute-binding protein, family 1, TC 3.A.1.1.3 sn-glycerol-3-phosphate-binding periplasmic protein ugpB. (438 aa)
ugpABinding-protein-dependent transport systems inner membrane component, TC 3.A.1.1.3 SN-glycerol-3-phosphate transport system permease protein ugpA. (295 aa)
ugpESn-glycerol-3-phosphate ABC transport system, inner membrane component; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane. (281 aa)
ugpCSn-glycerol 3-phosphate ABC transport system, ATP-binding component; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family. (357 aa)
yheRPutative NAD(P)H oxidoreductase; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB. (183 aa)
kefBGlutathione-regulated potassium-efflux system protein kefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. (601 aa)
ymcBUncharacterized protein ymcB precursor; Protein of unknown function DUF1017, Protein of unknown function (DUF1017). (238 aa)
yqjCIntersectin-1 (EH and SH3 domains protein 1); Protein of unknown function DUF1090, Protein of unknown function (DUF1090). (123 aa)
EAMY_3096Putative ClC family transporter; Chloride channel, voltage gated, TC 2.A.49.-.-The Chloride Carrier/Channel (ClC) Family. (563 aa)
EAMY_2833ABC transporter, ATP-binding protein, TC 3.A.1.-.-The ATP-binding Cassette (ABC) Superfamily. (224 aa)
folK2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (HPPK) (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) (PPPK). (160 aa)
EAMY_2783Protein of unknown function DUF1795, Domain of unknown function (DUF1795). (150 aa)
fhuBFerrichrome transport system permease protein fhuB (Ferrichrome uptake protein fhuB), TC 3.A.1.14.3 Ferrichrome transport system permease protein fhuB (Ferrichrome uptake protein fhuB); Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (658 aa)
metIBinding-protein-dependent transport systems inner membrane component, TC 3.A.1.24.1 D-methionine transport system permease protein MetI. (217 aa)
metNMethionine ABC transport system, ATP-binding component; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (373 aa)
proXSubstrate-binding region of ABC-type glycine betaine transport system, TC 3.A.1.12.1 Glycine betaine-binding periplasmic protein. (331 aa)
proWBinding-protein-dependent transport systems inner membrane component, TC 3.A.1.12.1 Glycine betaine/L-proline transport system permease protein proW. (387 aa)
proVGlycine betaine/L-proline transport ATP-binding subunit, ABC transporter, TC 3.A.1.12.1 Glycine betaine/L-proline transport ATP-binding protein proV. (398 aa)
tsxNucleoside-specific channel-forming protein, Tsx, TC 1.B.10.1.1 Nucleoside-specific channel-forming protein tsx. (288 aa)
yfhLNADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial precursor (NADH-ubiquinone oxidoreductase 23 kDa subunit) (Complex I-23kD) (CI-23kD) (Complex I-28.5kD) (CI-28.5kD). (139 aa)
EAMY_2521Protein of unknown function DUF1795, Domain of unknown function (DUF1795). (150 aa)
cysUSulfate ABC transport system, permease protein cysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (277 aa)
cysWSulphate ABC transporter permease protein 2, Binding-protein-dependent transport system inner membrane component, TC 3.A.1.6.1 Sulfate transport system permease protein cysW. (291 aa)
cysASulfate ABC transport system, ATP-binding component; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (362 aa)
EAMY_2393Binding-protein-dependent transport systems inner membrane component, TC 3.A.1.11.-The Polyamine/Opine/Phosphonate Uptake Transporter (POPT) Family. (422 aa)
potAPutative ABC transport system, ATP-binding component; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (361 aa)
nuoANADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (145 aa)
nuoCDNADH dehydrogenase I chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. (599 aa)
nuoFNADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (446 aa)
nuoGNADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (844 aa)
nuoJNADH dehydrogenase I chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (184 aa)
nuoLNADH-quinone oxidoreductase subunit L (NADH dehydrogenase I subunit L) (NDH-1 subunit L), NADH-plastoquinone oxidoreductase, chain 5. (612 aa)
ompCPorin, Gram-negative type, TC 1.B.1.1.3 outer membrane protein C precursor (porin ompC)(outer membrane protein 1B); Belongs to the Gram-negative porin family. (368 aa)
yegMMultidrug resistance protein precursor, HlyD family secretion protein, TC 8.A.1.6.2 Multidrug resistance protein mdtA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (405 aa)
amsHPolysaccharide export protein, Amylovoran biosynthesis protein amsH. (380 aa)
rfbB1Putative O-antigen export system ATP-binding protein, TC 3.A.1.103.1 O-antigen export system ATP-binding protein RfbB. (246 aa)
EAMY_2188Protein ea31. (291 aa)
yiuA3Uncharacterized protein HI1472 precursor; Periplasmic binding protein. (377 aa)
sitDABC transport system, inner membrane component, TC 3.A.1.15.7 SitD (Salmonella iron transporter: fur regulated). (278 aa)
sitCABC transport system, inner membrane component, 3.A.1.15.7 SitC (Salmonella iron transporter: fur regulated). (285 aa)
sitBABC transporter, ATP-binding protein, TC 3.A.1.15.7 SitB (Salmonella iron transporter: fur regulated). (267 aa)
EAMY_2140Hypothetical protein predicted by Glimmer/Critica. (322 aa)
efeUFerrous iron permease efeU (Ferrous iron uptake protein), TC 9.A.10.2.3 Ferrous iron permease efeU. (277 aa)
ycdOUPF0409 protein ycdO precursor; Protein of unknown function DUF451, Imelysin. (376 aa)
znuBPermease component of ABC transport system, TC 3.A.1.15.5 High-affinity zinc uptake system membrane protein znuB. (261 aa)
znuCPutative ABC zinc2+ transport system, ATP-binding component; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (252 aa)
EAMY_1768Hypothetical protein predicted by Glimmer/Critica. (69 aa)
ompFPorin, Gram-negative type, TC 1.B.1.1.1 outer membrane protein F precursor (porin OmpF) (Outer membrane protein 1A, IA, OR B). (357 aa)
scrYPorin, LamB type, TC 1.B.3.1.2 sucrose porin precursor. (514 aa)
ycfWLipoprotein releasing system, transmembrane protein, LolC/E family, TC 3.A.1.125.1 Lipoprotein releasing system transmembrane protein lolE. (414 aa)
ycfVLipoprotein-releasing system ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (234 aa)
ycfULipoprotein releasing system, transmembrane protein, LolC/E family, TC 3.A.1.125.1 Lipoprotein-releasing system transmembrane protein lolC. (399 aa)
ndhNADH dehydrogenase-like protein SAB0807, FAD-dependent pyridine nucleotide-disulphide oxidoreductase, Pyridine nucleotide-disulphide oxidoreductase. (430 aa)
ompAOuter membrane protein A precursor (Outer membrane protein II), TC 1.B.6.1.1 Outer membrane protein A; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. (355 aa)
ompNOuter membrane protein precursor (Porin); Porin, Gram-negative type, TC 1.B.1.1.-The General Bacterial Porin (GBP) Family. (367 aa)
cydDABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD, TC 3.A.1.129.1 Transport ATP-binding protein cydD. (589 aa)
cydCABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC, TC 3.A.1.129.1 Transport ATP-binding protein cydC. (576 aa)
potHPutrescine transport system permease protein, Binding-protein-dependent transport systems inner membrane component, TC 3.A.1.11.2 Putrescine transport system permease protein potH. (320 aa)
potGPutrescine ABC transport system, ATP-binding component; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (379 aa)
modFFused molybdate transporter subunit of ABC superfamily, ATP-binding component, TC 3.A.1.-.-The ATP-binding Cassette (ABC) Superfamily. (487 aa)
sdhBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit precursor (IP), iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (238 aa)
sdhASuccinate dehydrogenase [ubiquinone] flavoprotein subunit precursor (FP) (Flavoprotein subunit of complex II), FAD binding; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa)
sdhCSuccinate dehydrogenase cytochrome b556 subunit. (129 aa)
ybeCSec-independent protein translocase protein tatA/E homolog; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (62 aa)
acrAHlyD family secretion protein, efflux transporter, RND family, MFP subunit, TC 8.A.1.6.1 Acriflavine resistance protein A; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (397 aa)
cyoCCytochrome c oxidase subunit 3 (Cytochrome c oxidase polypeptide III). (204 aa)
cyoDCytochrome o ubiquinol oxidase protein cyoD (Ubiquinol oxidase chain D). (109 aa)
omp39Outer membrane protein 39; Porin, Gram-negative type, TC 1.B.1.1.8 Outer membrane protein 39. (384 aa)
mdtAPutative multidrug efflux system inner membrane protein; The Membrane Fusion Protein (MFP) Family, TC 8.A.1.6.2 Multidrug resistance protein mdtA. (421 aa)
yiuA1Uncharacterized lipoprotein MJ0085 precursor; [iron], Periplasmic binding protein. (376 aa)
exbDBiopolymer transport protein ExbD/TolR, TC 2.C.1.1.1 Biopolymer transport protein exbD. (140 aa)
tolCType I secretion outer membrane protein, TolC, Outer membrane efflux protein, TC 1.B.17.1.1 Outer membrane protein TolC precursor. (486 aa)
ompUOuter membrane protein; Porin, Gram-negative type, TC 1.B.1.2 The General Bacterial Porin (GBP) Family, OmpU subfamily. (383 aa)
ampH1beta-lactamase/D-alanine carboxypeptidase. (358 aa)
yjgPPredicted permease YjgP, TC 9.B.93.1.1 Inner membrane protein yjgP. (366 aa)
yhbGLPS export porin complex, cytoplasmic ABC-type ATPase subunit, TC 1.B.42.1.2 Uncharacterized ABC transporter ATP-binding protein yhbG. (241 aa)
tatCSec-independent protein translocase protein tatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (253 aa)
tatBSec-independent protein translocase protein tatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (179 aa)
tatASec-independent protein translocase protein tatA homolog; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (85 aa)
argHArgininosuccinate lyase (Arginosuccinase) (ASAL). (457 aa)
Your Current Organism:
Erwinia amylovora
NCBI taxonomy Id: 665029
Other names: E. amylovora CFBP1430, Erwinia amylovora CFBP1430, Erwinia amylovora str. CFBP1430, Erwinia amylovora strain CFBP1430
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