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alsS alsS coaBC coaBC kdtB kdtB ilvG ilvG ilvM ilvM ilvE1 ilvE1 ilvD ilvD ilvC ilvC coaA coaA mazG mazG yajB yajB apbA apbA ilvE3 ilvE3 acpS acpS panB panB panC1 panC1 panD panD coaE coaE ilvH ilvH ilvI ilvI panE panE
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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alsSAcetolactate synthase, catabolic (ALS), Thiamine pyrophosphate enzyme; Belongs to the TPP enzyme family. (559 aa)
coaBCBifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (404 aa)
kdtBPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (158 aa)
ilvGAcetolactate synthase isozyme III large subunit (AHAS-III) (Acetohydroxy-acid synthase III large subunit) (ALS-III). (560 aa)
ilvMAcetolactate synthase isozyme II small subunit (AHAS-II) (Acetohydroxy-acid synthase II small subunit) (ALS-II). (85 aa)
ilvE1Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (308 aa)
ilvDDihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (616 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (492 aa)
coaAPantothenate kinase (Pantothenic acid kinase). (316 aa)
mazGProtein mazG; NTP pyrophosphohydrolase MazG, bacterial, MazG nucleotide pyrophosphohydrolase domain, mazG: MazG family protein. (264 aa)
yajBAcyl carrier protein phosphodiesterase (ACP phosphodiesterase), Protein of unknown function DUF479, Protein of unknown function, DUF479. (193 aa)
apbA2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (306 aa)
ilvE3Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (322 aa)
acpSHolo-acyl carrier protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (126 aa)
panB3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (264 aa)
panC1Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (284 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (126 aa)
coaEDephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (203 aa)
ilvHAcetolactate synthase isozyme III small subunit (AHAS-III) (Acetohydroxy-acid synthase III small subunit) (ALS-III). (163 aa)
ilvIAcetolactate synthase large subunit (AHAS) (Acetohydroxy-acid synthase large subunit) (ALS), Thiamine pyrophosphate enzyme. (574 aa)
panEProbable 2-dehydropantoate 2-reductase (KPA reductase) (KPR). (304 aa)
Your Current Organism:
Erwinia amylovora
NCBI taxonomy Id: 665029
Other names: E. amylovora CFBP1430, Erwinia amylovora CFBP1430, Erwinia amylovora str. CFBP1430, Erwinia amylovora strain CFBP1430
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