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alsS | Acetolactate synthase, catabolic (ALS), Thiamine pyrophosphate enzyme; Belongs to the TPP enzyme family. (559 aa) | ||||
coaBC | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (404 aa) | ||||
kdtB | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (158 aa) | ||||
ilvG | Acetolactate synthase isozyme III large subunit (AHAS-III) (Acetohydroxy-acid synthase III large subunit) (ALS-III). (560 aa) | ||||
ilvM | Acetolactate synthase isozyme II small subunit (AHAS-II) (Acetohydroxy-acid synthase II small subunit) (ALS-II). (85 aa) | ||||
ilvE1 | Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (308 aa) | ||||
ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (616 aa) | ||||
ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (492 aa) | ||||
coaA | Pantothenate kinase (Pantothenic acid kinase). (316 aa) | ||||
mazG | Protein mazG; NTP pyrophosphohydrolase MazG, bacterial, MazG nucleotide pyrophosphohydrolase domain, mazG: MazG family protein. (264 aa) | ||||
yajB | Acyl carrier protein phosphodiesterase (ACP phosphodiesterase), Protein of unknown function DUF479, Protein of unknown function, DUF479. (193 aa) | ||||
apbA | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (306 aa) | ||||
ilvE3 | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (322 aa) | ||||
acpS | Holo-acyl carrier protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (126 aa) | ||||
panB | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (264 aa) | ||||
panC1 | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (284 aa) | ||||
panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (126 aa) | ||||
coaE | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (203 aa) | ||||
ilvH | Acetolactate synthase isozyme III small subunit (AHAS-III) (Acetohydroxy-acid synthase III small subunit) (ALS-III). (163 aa) | ||||
ilvI | Acetolactate synthase large subunit (AHAS) (Acetohydroxy-acid synthase large subunit) (ALS), Thiamine pyrophosphate enzyme. (574 aa) | ||||
panE | Probable 2-dehydropantoate 2-reductase (KPA reductase) (KPR). (304 aa) |