(18 nodes) Butanoate metabolism network (Sclerotinia sclerotiorum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	SS1G_00237	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (288 aa)
	SS1G_00672	Uncharacterized protein. (314 aa)
	SS1G_00795	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (579 aa)
	SS1G_02611	Succinate-semialdehyde dehydrogenase. (498 aa)
	SS1G_02923	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (413 aa)
	SS1G_03926	ACT domain-containing protein. (323 aa)
	SS1G_05050	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (557 aa)
	SS1G_06550	Acetolactate synthase. (699 aa)
	SS1G_06865	Aldedh domain-containing protein. (498 aa)
	SS1G_07083	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (495 aa)
	SS1G_07467	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (546 aa)
	SS1G_09974	DAO domain-containing protein. (408 aa)
	SS1G_10644	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (455 aa)
	SS1G_10681	Pyruvate carboxyltransferase domain-containing protein. (375 aa)
	SS1G_12152	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
	SS1G_11735	Uncharacterized protein. (493 aa)
	SS1G_12031	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (501 aa)
	SS1G_14433	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (459 aa)

Your Current Organism:

Sclerotinia sclerotiorum

NCBI taxonomy Id: 665079
Other names: S. sclerotiorum 1980 UF-70, Sclerotinia sclerotiorum 1980 UF-70

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SS1G_00237	SS1G_00672	A7E4L5	A7E5U7	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	Uncharacterized protein.	0.998
SS1G_00237	SS1G_02923	A7E4L5	A7EC84	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.668
SS1G_00237	SS1G_07467	A7E4L5	A7EQ67	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.412
SS1G_00237	SS1G_10681	A7E4L5	A7EZB4	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	Pyruvate carboxyltransferase domain-containing protein.	0.574
SS1G_00237	SS1G_12031	A7E4L5	A7F435	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.412
SS1G_00237	SS1G_12152	A7E4L5	A7F2K4	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.696
SS1G_00672	SS1G_00237	A7E5U7	A7E4L5	Uncharacterized protein.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.998
SS1G_00672	SS1G_02923	A7E5U7	A7EC84	Uncharacterized protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.987
SS1G_00672	SS1G_07467	A7E5U7	A7EQ67	Uncharacterized protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.948
SS1G_00672	SS1G_10644	A7E5U7	A7EZ77	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.903
SS1G_00672	SS1G_10681	A7E5U7	A7EZB4	Uncharacterized protein.	Pyruvate carboxyltransferase domain-containing protein.	0.574
SS1G_00672	SS1G_12031	A7E5U7	A7F435	Uncharacterized protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.948
SS1G_00672	SS1G_12152	A7E5U7	A7F2K4	Uncharacterized protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.988
SS1G_00672	SS1G_14433	A7E5U7	A7FA02	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.903
SS1G_00795	SS1G_02611	A7E670	A7EBC5	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	Succinate-semialdehyde dehydrogenase.	0.570
SS1G_00795	SS1G_05050	A7E670	A7EIA7	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	0.906
SS1G_00795	SS1G_07083	A7E670	A7EP34	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.960
SS1G_00795	SS1G_09974	A7E670	A7EXB3	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	DAO domain-containing protein.	0.801
SS1G_00795	SS1G_11735	A7E670	A7F389	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	Uncharacterized protein.	0.900
SS1G_02611	SS1G_00795	A7EBC5	A7E670	Succinate-semialdehyde dehydrogenase.	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	0.570