STRINGSTRING
ASAC_0026 ASAC_0026 ASAC_0027 ASAC_0027 ASAC_0029 ASAC_0029 ASAC_0030 ASAC_0030 cobB cobB ASAC_0096 ASAC_0096 ASAC_0097 ASAC_0097 ASAC_0098 ASAC_0098 ASAC_0099 ASAC_0099 ASAC_0119 ASAC_0119 ASAC_0155 ASAC_0155 ASAC_0176 ASAC_0176 ASAC_0245 ASAC_0245 ASAC_0263 ASAC_0263 ASAC_0264 ASAC_0264 ASAC_0265 ASAC_0265 ASAC_0266 ASAC_0266 ASAC_0267 ASAC_0267 ASAC_0288 ASAC_0288 ASAC_0321 ASAC_0321 gcvPB gcvPB gcvPA gcvPA ASAC_0461 ASAC_0461 ASAC_0498 ASAC_0498 ASAC_0512 ASAC_0512 ASAC_0537 ASAC_0537 ASAC_0539 ASAC_0539 ASAC_0545 ASAC_0545 ASAC_0546 ASAC_0546 ASAC_0569 ASAC_0569 ASAC_0582 ASAC_0582 ASAC_0597 ASAC_0597 ASAC_0614 ASAC_0614 ASAC_0693 ASAC_0693 rbsK rbsK ASAC_0739 ASAC_0739 ASAC_0817 ASAC_0817 eno eno ASAC_0852 ASAC_0852 ASAC_0871 ASAC_0871 ASAC_0874 ASAC_0874 ASAC_0875 ASAC_0875 ASAC_0878 ASAC_0878 ASAC_0880 ASAC_0880 ASAC_0891 ASAC_0891 gap gap ASAC_0978 ASAC_0978 ASAC_0997 ASAC_0997 ASAC_1021 ASAC_1021 ASAC_1025 ASAC_1025 ASAC_1031 ASAC_1031 ASAC_1035 ASAC_1035 ASAC_1036 ASAC_1036 ASAC_1037 ASAC_1037 ASAC_1038 ASAC_1038 ASAC_1039 ASAC_1039 ASAC_1042 ASAC_1042 ASAC_1049 ASAC_1049 ASAC_1053 ASAC_1053 ASAC_1054 ASAC_1054 ASAC_1055 ASAC_1055 ASAC_1056 ASAC_1056 ASAC_1063 ASAC_1063 prs prs sucD sucD sucC sucC ASAC_1099 ASAC_1099 ASAC_1156 ASAC_1156 prpB prpB ASAC_1207 ASAC_1207 ASAC_1210 ASAC_1210 fbp fbp tpiA tpiA ASAC_1232 ASAC_1232 ASAC_1235 ASAC_1235 ASAC_1260 ASAC_1260 ASAC_1261 ASAC_1261 ASAC_1262 ASAC_1262 ASAC_1263 ASAC_1263 ASAC_1264 ASAC_1264 ASAC_1277 ASAC_1277 ASAC_1278 ASAC_1278 ASAC_1285 ASAC_1285 ASAC_1289 ASAC_1289 ASAC_1290 ASAC_1290 ASAC_1291 ASAC_1291 ASAC_1292 ASAC_1292 ASAC_1304 ASAC_1304 ASAC_1329 ASAC_1329 ASAC_1330 ASAC_1330 deoC deoC ASAC_1338 ASAC_1338 ASAC_1360 ASAC_1360 ASAC_1371 ASAC_1371 pgk pgk ASAC_1390 ASAC_1390 ASAC_1423 ASAC_1423 ASAC_1433 ASAC_1433 mvk mvk ASAC_1440 ASAC_1440 ASAC_1441 ASAC_1441 ASAC_1442 ASAC_1442 ASAC_1443 ASAC_1443 gcvH gcvH gpmA gpmA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ASAC_0026Putative 3-ketoacyl-CoA thiolase. (396 aa)
ASAC_0027DUF35 domain containing protein. (179 aa)
ASAC_0029Fructose-1,6-bisphosphate aldolase. (288 aa)
ASAC_0030ATP-dependent 6-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (320 aa)
cobBNAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily. (264 aa)
ASAC_0096Pyruvate:ferredoxin oxidoreductase (POR) and putative 2-oxoglutarate:ferredoxin oxidoreductase (KGOR), gamma subunitubunit. (192 aa)
ASAC_0097Pyruvate:ferredoxin oxidoreductase (POR) and putative 2-oxoglutarate:ferredoxin oxidoreductase (KGOR), delta subunit. (112 aa)
ASAC_0098Pyruvate:ferredoxin oxidoreductase (POR), alpha subunit. (397 aa)
ASAC_0099Pyruvate:ferredoxin oxidoreductase (POR), beta subunit. (324 aa)
ASAC_0119Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (335 aa)
ASAC_0155Acyl-CoA dehydrogenase. (399 aa)
ASAC_0176Enoyl-CoA hydratase. (261 aa)
ASAC_0245Glyceraldehyde-3-phosphate:ferredoxin oxidoreductase (GAPOR). (650 aa)
ASAC_0263Hypothetical protein. (270 aa)
ASAC_0264Electron transfer flavoprotein alpha-subunit. (368 aa)
ASAC_0265Electron transfer flavoprotein beta-subunit. (284 aa)
ASAC_0266Ferredoxin like protein. (101 aa)
ASAC_0267Electron transfer flavoprotein-quinone oxidoreductase. (434 aa)
ASAC_0288Putative L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (308 aa)
ASAC_0321Putative 3-ketoacyl-CoA thiolase. (397 aa)
gcvPBGlycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (521 aa)
gcvPAGlycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (464 aa)
ASAC_0461Aldose 1-epimerase. (263 aa)
ASAC_0498Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (211 aa)
ASAC_0512Malate dehydrogenase. (451 aa)
ASAC_0537Fumarate hydratase. (440 aa)
ASAC_0539Acyl-CoA ligase (acyl-CoA synthetase). (639 aa)
ASAC_0545Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate. (236 aa)
ASAC_0546Putative succinyl-CoA:3-ketoacid-CoA ligase, fused subunits A and B. (556 aa)
ASAC_0569Glycine cleavage system aminomethyltransferase T. (374 aa)
ASAC_0582Acyl-CoA dehydrogenase. (384 aa)
ASAC_0597Acyl-CoA ligase (acyl-CoA synthetase). (659 aa)
ASAC_0614NAD(P)+-dependent formate dehydrogenase, alpha subunit. (718 aa)
ASAC_0693Fe-S cluster-containing protein. (167 aa)
rbsK2-Keto-3-deoxy-gluconate kinase (KDGK); Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (300 aa)
ASAC_0739Pyruvate, phosphate dikinase (PPDK). (972 aa)
ASAC_0817Isocitrate dehydrogenase (NADP+-dependent). (429 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa)
ASAC_0852Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase). (225 aa)
ASAC_0871Citrate synthase. (398 aa)
ASAC_0874Putative 2-oxoacid:ferredoxin oxidoreductase, beta subunit. (304 aa)
ASAC_0875Putative 2-oxoacid:ferredoxin oxidoreductase, alpha subunit. (649 aa)
ASAC_0878ADP-dependent hexokinase (HK). (328 aa)
ASAC_0880Pyruvate kinase (PYK); Belongs to the pyruvate kinase family. (460 aa)
ASAC_0891Phosphoglycerate kinase. (409 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase (GAPDH). (348 aa)
ASAC_0978Malate dehydrogenase. (446 aa)
ASAC_0997Acyl-CoA ligase (acyl-CoA synthetase). (658 aa)
ASAC_1021Glycerate kinase. (439 aa)
ASAC_10252-methylcitrate dehydratase. (462 aa)
ASAC_10313-Hydroxyacyl-CoA dehydrogenase. (672 aa)
ASAC_1035Putative hydroxymethylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family. (351 aa)
ASAC_1036Putative 3-ketoacyl-CoA thiolase. (381 aa)
ASAC_1037Predicted nucleic-acid-binding protein containing a Zn-ribbon. (139 aa)
ASAC_10383-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. (419 aa)
ASAC_10393-hydroxyisobutyrate dehydrogenase. (292 aa)
ASAC_1042Acyl-CoA dehydrogenase. (409 aa)
ASAC_1049Ribose-5-phosphate isomerase. (240 aa)
ASAC_10532-Ketoisovalerate:ferredoxin oxidoreductase (VOR), beta subunit. (305 aa)
ASAC_10542-Ketoisovalerate:ferredoxin oxidoreductase (VOR), alpha subunit. (400 aa)
ASAC_10552-Ketoisovalerate:ferredoxin oxidoreductase (VOR), delta subunit. (87 aa)
ASAC_10562-Ketoisovalerate:ferredoxin oxidoreductase (VOR), gamma subunit. (183 aa)
ASAC_1063Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide E3 component-like enzyme; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (462 aa)
prsPhosphoribosyl pyrophosphate synthase (PRPP synthase); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (294 aa)
sucDSuccinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa)
sucCSuccinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (382 aa)
ASAC_1099Phosphoglycerate mutase (PGM). (427 aa)
ASAC_1156Phospho-sugar mutase. (470 aa)
prpBPutative carboxyvinyl-carboxyphosphonate phosphorylmutase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (314 aa)
ASAC_1207Phosphoglucose isomerase (PGI). (289 aa)
ASAC_1210Acetyl coenzym A synthetase (ADP-forming). (712 aa)
fbpFructose-1,6-bisphosphatase (FBP); Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (383 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (225 aa)
ASAC_1232Acyl-CoA dehydrogenase. (344 aa)
ASAC_1235Serine hydroxymethyltransferase. (433 aa)
ASAC_1260Acyl-CoA ligase (acyl-CoA synthetase). (656 aa)
ASAC_1261Putative 3-ketoacyl-CoA thiolase. (391 aa)
ASAC_1262Putative 3-ketoacyl-CoA thiolase. (394 aa)
ASAC_1263DUF35 domain containing protein. (178 aa)
ASAC_1264DUF35 domain containing protein. (154 aa)
ASAC_1277Fumarase (fumarate hydratase) class I, N-terminal domain protein. (302 aa)
ASAC_1278Fumarase (fumarate hydratase) class I, C-terminal domain protein. (211 aa)
ASAC_1285Aldolase class II protein. (192 aa)
ASAC_1289Electron transfer flavoprotein beta-subunit. (268 aa)
ASAC_1290Electron transfer flavoprotein alpha-subunit. (305 aa)
ASAC_1291Putative 2-oxoglutarate:ferredoxin oxidoreductase (KGOR), alpha subunit. (638 aa)
ASAC_1292Putative 2-oxooglutarate:ferredoxin oxidoreductase (KGOR), beta subunit. (319 aa)
ASAC_1304Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (424 aa)
ASAC_1329Dehydrogenase (flavoprotein)-like protein. (386 aa)
ASAC_1330Aconitase. (902 aa)
deoCProbable deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (248 aa)
ASAC_1338D-lactate dehydrogenase. (478 aa)
ASAC_1360Putative dehydrogenase. (284 aa)
ASAC_1371Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide E3 component-like enzyme; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (462 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (414 aa)
ASAC_1390Beta-galactosidase; Belongs to the glycosyl hydrolase 1 family. (490 aa)
ASAC_1423Glyceraldehyde-3-phosphate dehydrogenase (non-phosphorylating) (GAPN). (514 aa)
ASAC_1433Enoyl-CoA hydratase. (251 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (304 aa)
ASAC_1440Succinate:quinone oxidoreductase, iron-sulfur subunit B. (301 aa)
ASAC_1441Succinate:quinone oxidoreductase, hydrophobic anchor subunit D. (119 aa)
ASAC_1442Succinate:quinone oxidoreductase, cytochrome b subunit C. (163 aa)
ASAC_1443Succinate:quinone oxidoreductase, flavoprotein subunit A. (583 aa)
gcvHProbable glycine cleavage system H protein 1; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (141 aa)
gpmA2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (203 aa)
Your Current Organism:
Acidilobus saccharovorans
NCBI taxonomy Id: 666510
Other names: A. saccharovorans 345-15, Acidilobus saccharovorans 345-15, Acidilobus saccharovorans str. 345-15, Acidilobus saccharovorans strain 345-15, Acidilobus sp. 345-15
Server load: low (12%) [HD]