STRINGSTRING
cobB cobB ASAC_0096 ASAC_0096 ASAC_0097 ASAC_0097 ASAC_0098 ASAC_0098 ASAC_0099 ASAC_0099 ASAC_0288 ASAC_0288 gcvPB gcvPB gcvPA gcvPA ASAC_0498 ASAC_0498 ASAC_0512 ASAC_0512 ASAC_0537 ASAC_0537 ASAC_0539 ASAC_0539 ASAC_0546 ASAC_0546 ASAC_0569 ASAC_0569 ASAC_0597 ASAC_0597 ASAC_0614 ASAC_0614 ASAC_0693 ASAC_0693 ASAC_0739 ASAC_0739 ASAC_0817 ASAC_0817 ASAC_0852 ASAC_0852 ASAC_0871 ASAC_0871 ASAC_0874 ASAC_0874 ASAC_0875 ASAC_0875 ASAC_0880 ASAC_0880 ASAC_0978 ASAC_0978 ASAC_0997 ASAC_0997 ASAC_1025 ASAC_1025 ASAC_1039 ASAC_1039 ASAC_1053 ASAC_1053 ASAC_1055 ASAC_1055 ASAC_1056 ASAC_1056 ASAC_1063 ASAC_1063 sucD sucD sucC sucC prpB prpB ASAC_1210 ASAC_1210 ASAC_1235 ASAC_1235 ASAC_1260 ASAC_1260 ASAC_1277 ASAC_1277 ASAC_1278 ASAC_1278 ASAC_1291 ASAC_1291 ASAC_1292 ASAC_1292 ASAC_1304 ASAC_1304 ASAC_1330 ASAC_1330 ASAC_1360 ASAC_1360 ASAC_1371 ASAC_1371 ASAC_1440 ASAC_1440 ASAC_1441 ASAC_1441 ASAC_1442 ASAC_1442 ASAC_1443 ASAC_1443 gcvH gcvH
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
cobBNAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily. (264 aa)
ASAC_0096Pyruvate:ferredoxin oxidoreductase (POR) and putative 2-oxoglutarate:ferredoxin oxidoreductase (KGOR), gamma subunitubunit. (192 aa)
ASAC_0097Pyruvate:ferredoxin oxidoreductase (POR) and putative 2-oxoglutarate:ferredoxin oxidoreductase (KGOR), delta subunit. (112 aa)
ASAC_0098Pyruvate:ferredoxin oxidoreductase (POR), alpha subunit. (397 aa)
ASAC_0099Pyruvate:ferredoxin oxidoreductase (POR), beta subunit. (324 aa)
ASAC_0288Putative L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (308 aa)
gcvPBGlycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (521 aa)
gcvPAGlycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (464 aa)
ASAC_0498Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (211 aa)
ASAC_0512Malate dehydrogenase. (451 aa)
ASAC_0537Fumarate hydratase. (440 aa)
ASAC_0539Acyl-CoA ligase (acyl-CoA synthetase). (639 aa)
ASAC_0546Putative succinyl-CoA:3-ketoacid-CoA ligase, fused subunits A and B. (556 aa)
ASAC_0569Glycine cleavage system aminomethyltransferase T. (374 aa)
ASAC_0597Acyl-CoA ligase (acyl-CoA synthetase). (659 aa)
ASAC_0614NAD(P)+-dependent formate dehydrogenase, alpha subunit. (718 aa)
ASAC_0693Fe-S cluster-containing protein. (167 aa)
ASAC_0739Pyruvate, phosphate dikinase (PPDK). (972 aa)
ASAC_0817Isocitrate dehydrogenase (NADP+-dependent). (429 aa)
ASAC_0852Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase). (225 aa)
ASAC_0871Citrate synthase. (398 aa)
ASAC_0874Putative 2-oxoacid:ferredoxin oxidoreductase, beta subunit. (304 aa)
ASAC_0875Putative 2-oxoacid:ferredoxin oxidoreductase, alpha subunit. (649 aa)
ASAC_0880Pyruvate kinase (PYK); Belongs to the pyruvate kinase family. (460 aa)
ASAC_0978Malate dehydrogenase. (446 aa)
ASAC_0997Acyl-CoA ligase (acyl-CoA synthetase). (658 aa)
ASAC_10252-methylcitrate dehydratase. (462 aa)
ASAC_10393-hydroxyisobutyrate dehydrogenase. (292 aa)
ASAC_10532-Ketoisovalerate:ferredoxin oxidoreductase (VOR), beta subunit. (305 aa)
ASAC_10552-Ketoisovalerate:ferredoxin oxidoreductase (VOR), delta subunit. (87 aa)
ASAC_10562-Ketoisovalerate:ferredoxin oxidoreductase (VOR), gamma subunit. (183 aa)
ASAC_1063Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide E3 component-like enzyme; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (462 aa)
sucDSuccinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa)
sucCSuccinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (382 aa)
prpBPutative carboxyvinyl-carboxyphosphonate phosphorylmutase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (314 aa)
ASAC_1210Acetyl coenzym A synthetase (ADP-forming). (712 aa)
ASAC_1235Serine hydroxymethyltransferase. (433 aa)
ASAC_1260Acyl-CoA ligase (acyl-CoA synthetase). (656 aa)
ASAC_1277Fumarase (fumarate hydratase) class I, N-terminal domain protein. (302 aa)
ASAC_1278Fumarase (fumarate hydratase) class I, C-terminal domain protein. (211 aa)
ASAC_1291Putative 2-oxoglutarate:ferredoxin oxidoreductase (KGOR), alpha subunit. (638 aa)
ASAC_1292Putative 2-oxooglutarate:ferredoxin oxidoreductase (KGOR), beta subunit. (319 aa)
ASAC_1304Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (424 aa)
ASAC_1330Aconitase. (902 aa)
ASAC_1360Putative dehydrogenase. (284 aa)
ASAC_1371Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide E3 component-like enzyme; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (462 aa)
ASAC_1440Succinate:quinone oxidoreductase, iron-sulfur subunit B. (301 aa)
ASAC_1441Succinate:quinone oxidoreductase, hydrophobic anchor subunit D. (119 aa)
ASAC_1442Succinate:quinone oxidoreductase, cytochrome b subunit C. (163 aa)
ASAC_1443Succinate:quinone oxidoreductase, flavoprotein subunit A. (583 aa)
gcvHProbable glycine cleavage system H protein 1; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (141 aa)
Your Current Organism:
Acidilobus saccharovorans
NCBI taxonomy Id: 666510
Other names: A. saccharovorans 345-15, Acidilobus saccharovorans 345-15, Acidilobus saccharovorans str. 345-15, Acidilobus saccharovorans strain 345-15, Acidilobus sp. 345-15
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