STRINGSTRING
ASAC_1128 ASAC_1128 hisS hisS tmcA tmcA ASAC_1439 ASAC_1439 ASAC_1428 ASAC_1428 nep1 nep1 tyrS tyrS ASAC_1366 ASAC_1366 ASAC_1364 ASAC_1364 eif1a eif1a ASAC_1323 ASAC_1323 ASAC_1320 ASAC_1320 flpA flpA ASAC_1312 ASAC_1312 gatD gatD gatE gatE ASAC_1306 ASAC_1306 ASAC_1302 ASAC_1302 ASAC_1275 ASAC_1275 rpl2 rpl2 rps8e rps8e ASAC_1251 ASAC_1251 tfb tfb eif5a eif5a rpl10e rpl10e rpl15 rpl15 rpl30 rpl30 rps5 rps5 rpl18 rpl18 rpl19e rpl19e ASAC_1221 ASAC_1221 rpl6 rpl6 rps19e rps19e ASAC_1197 ASAC_1197 csl4 csl4 rnp4 rnp4 rps10 rps10 tuf tuf rps7 rps7 rps12 rps12 nusA nusA rpl30e rpl30e rpoA2 rpoA2 ASAC_1176 ASAC_1176 ASAC_1175 ASAC_1175 ASAC_1174 ASAC_1174 ASAC_1160 ASAC_1160 leuS leuS rpl24e rpl24e rpl37ae rpl37ae ASAC_1135 ASAC_1135 rpl15e rpl15e eif6 eif6 ASAC_0620 ASAC_0620 rpl39e rpl39e cca cca rpl18a rpl18a ASAC_1110 ASAC_1110 rpl40e rpl40e ASAC_1104 ASAC_1104 rps3ae rps3ae rps15 rps15 rps6e rps6e eif2g eif2g infB infB ASAC_1082 ASAC_1082 rps28e rps28e ASAC_1069 ASAC_1069 ASAC_1068 ASAC_1068 tiaS tiaS ASAC_1044 ASAC_1044 ASAC_1023 ASAC_1023 ASAC_1020 ASAC_1020 rpl7ae rpl7ae rps13 rps13 rps4 rps4 rps11 rps11 rpoD rpoD rpl18e rpl18e rpl13 rpl13 rps9 rps9 ASAC_1004 ASAC_1004 rps2 rps2 pth pth spt5 spt5 ASAC_0936 ASAC_0936 rpl4 rpl4 rpl23 rpl23 ASAC_0920 ASAC_0920 rpl37e rpl37e ASAC_0917 ASAC_0917 ASAC_0915 ASAC_0915 ASAC_0905 ASAC_0905 rtcA rtcA ASAC_0797 ASAC_0797 ASAC_0752 ASAC_0752 ASAC_0706 ASAC_0706 ASAC_0631 ASAC_0631 ASAC_0034 ASAC_0034 ASAC_0077 ASAC_0077 ASAC_0094 ASAC_0094 lysS lysS glyS glyS ASAC_0139 ASAC_0139 ASAC_0140 ASAC_0140 ef1b ef1b ASAC_0171 ASAC_0171 pus10 pus10 rpl14e rpl14e rnz rnz ASAC_0193 ASAC_0193 tbp tbp rpl44e rpl44e nop10 nop10 ASAC_0203 ASAC_0203 ASAC_0213 ASAC_0213 ASAC_0215 ASAC_0215 ASAC_0219 ASAC_0219 rps8 rps8 rps14 rps14 rpl5 rpl5 rps4e rps4e rpl24 rpl24 rpl14 rpl14 rps17 rps17 rnp1 rnp1 rpl29 rpl29 rps3 rps3 rpl22 rpl22 rps19p rps19p metG metG cysS cysS rpl11 rpl11 alaS alaS rpl12 rpl12 rpl10 rpl10 rpl1 rpl1 taw1 taw1 ASAC_0263 ASAC_0263 eif2b eif2b serS serS ASAC_0276 ASAC_0276 prf1 prf1 ASAC_0285 ASAC_0285 ASAC_0287 ASAC_0287 ASAC_0292 ASAC_0292 tfe tfe ASAC_0297 ASAC_0297 ASAC_0306 ASAC_0306 tgtA tgtA ASAC_0309 ASAC_0309 rps17e rps17e ASAC_0324 ASAC_0324 gltX gltX ASAC_0337 ASAC_0337 pheS pheS argS argS ileS ileS ASAC_0348 ASAC_0348 ASAC_0365 ASAC_0365 fusA fusA proS proS ASAC_0396 ASAC_0396 ASAC_0400 ASAC_0400 ASAC_0403 ASAC_0403 ASAC_0410 ASAC_0410 rpoK rpoK rpl21e rpl21e ASAC_0429 ASAC_0429 ASAC_0444 ASAC_0444 ASAC_0445 ASAC_0445 ASAC_0451 ASAC_0451 ASAC_0455 ASAC_0455 aspS aspS ASAC_0465 ASAC_0465 gatA gatA gatB gatB ASAC_0474 ASAC_0474 ASAC_0477 ASAC_0477 ASAC_0502 ASAC_0502 trpS trpS ASAC_0533 ASAC_0533 ASAC_0547 ASAC_0547 ASAC_0552 ASAC_0552 ASAC_0566 ASAC_0566 ASAC_0589 ASAC_0589 kae1 kae1 rps27ae rps27ae rps24e rps24e ASAC_0599 ASAC_0599 thiI thiI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ASAC_1128Hypothetical protein. (78 aa)
hisSHistidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (432 aa)
tmcAPredicted P-loop ATPase fused to an acetyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (825 aa)
ASAC_1439Protein L-isoaspartate methyltransferase. (259 aa)
ASAC_1428Hypothetical protein. (55 aa)
nep1Probable ribosome biogenesis protein NEP1-like protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. (215 aa)
tyrSTyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. (358 aa)
ASAC_1366GTPase or GTP-binding protein-like protein. (334 aa)
ASAC_1364Predicted RNA-binding protein. (197 aa)
eif1aTranslation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (110 aa)
ASAC_1323Hypothetical protein. (144 aa)
ASAC_1320Hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. (146 aa)
flpAFibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (219 aa)
ASAC_1312Hypothetical protein. (50 aa)
gatDGlutamyl-tRNA(Gln) amidotransferase subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (461 aa)
gatEGlutamyl-tRNA(Gln) amidotransferase subunit E; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (642 aa)
ASAC_1306Hypothetical protein. (183 aa)
ASAC_1302SirA family protein. (80 aa)
ASAC_1275Hydrogenase expression/formation factor-like protein. (361 aa)
rpl250S ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (237 aa)
rps8e30S ribosomal protein S8e. (133 aa)
ASAC_1251Hypothetical protein. (103 aa)
tfbTranscription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (318 aa)
eif5aTranslation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (136 aa)
rpl10e50S ribosomal protein L10e; Belongs to the universal ribosomal protein uL16 family. (182 aa)
rpl1550S ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (166 aa)
rpl3050S ribosomal protein L30P. (157 aa)
rps530S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (199 aa)
rpl1850S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (212 aa)
rpl19e50S ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (156 aa)
ASAC_122150S ribosomal protein L32e. (135 aa)
rpl650S ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (182 aa)
rps19e30S ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (151 aa)
ASAC_1197DNA-directed RNA polymerase II subunit RPB11. (101 aa)
csl4Exosome complex RNA-binding like-protein Cs14; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (201 aa)
rnp4Ribonuclease P protein component 4; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (103 aa)
rps1030S ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa)
tufElongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (436 aa)
rps730S ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (203 aa)
rps1230S ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (145 aa)
nusATranscription elongation factor NusA-like protein; Participates in transcription termination. Belongs to the NusA family. (150 aa)
rpl30e50S ribosomal protein L30e; Belongs to the eukaryotic ribosomal protein eL30 family. (104 aa)
rpoA2DNA-directed RNA polymerase subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (446 aa)
ASAC_1176DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (889 aa)
ASAC_1175DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1179 aa)
ASAC_1174DNA-directed RNA polymerase subunit H. (68 aa)
ASAC_1160Predicted ATPase. (263 aa)
leuSLeucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (962 aa)
rpl24e50S ribosomal protein L24e; Binds to the 23S rRNA. (63 aa)
rpl37ae50S ribosomal protein L37Ae; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily. (82 aa)
ASAC_1135Hypothetical protein; Probably involved in the biogenesis of the ribosome. (195 aa)
rpl15e50S ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family. (227 aa)
eif6Translation initiation factor 6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (226 aa)
ASAC_0620Hypothetical protein. (149 aa)
rpl39eHypothetical protein; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa)
ccaCCA-adding enzyme; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (457 aa)
rpl18a50S ribosomal protein LX. (88 aa)
ASAC_111030S ribosomal protein S26e. (95 aa)
rpl40e50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. (57 aa)
ASAC_1104Transcription elongation factor, S-II like-protein. (96 aa)
rps3ae30S ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. (223 aa)
rps1530S ribosomal protein S15P/S13e. (152 aa)
rps6e30S ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. (246 aa)
eif2gTranslation initiation factor 2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (424 aa)
infBProbable translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (609 aa)
ASAC_1082Ribonuclease P-related protein. (97 aa)
rps28e30S ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family. (83 aa)
ASAC_1069TRNA-binding protein. (122 aa)
ASAC_1068DNA-directed RNA polymerase subunit E. (193 aa)
tiaSHypothetical protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (437 aa)
ASAC_1044Hypothetical protein. (112 aa)
ASAC_1023Methyltransferase. (272 aa)
ASAC_1020Selenocysteine-specific translation elongation factor-like protein. (304 aa)
rpl7ae50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (127 aa)
rps1330S ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (173 aa)
rps430S ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (177 aa)
rps1130S ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (131 aa)
rpoDDNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. (287 aa)
rpl18eRibosomal protein L15; Belongs to the eukaryotic ribosomal protein eL18 family. (118 aa)
rpl1350S ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (156 aa)
rps930S ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (167 aa)
ASAC_1004DNA-directed RNA polymerase subunit N. (72 aa)
rps230S ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (239 aa)
pthPeptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. (119 aa)
spt5Putative transcription antitermination protein nusG; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (172 aa)
ASAC_093650S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (329 aa)
rpl450S ribosomal protein L4P; Forms part of the polypeptide exit tunnel. (276 aa)
rpl2350S ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (88 aa)
ASAC_0920LSM domain containing protein. (78 aa)
rpl37e50S ribosomal protein L37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (62 aa)
ASAC_0917ATPase, PP-loop superfamily. (338 aa)
ASAC_0915PUA domain containing protein. (166 aa)
ASAC_0905DUF790 domain containing protein. (487 aa)
rtcAProbable RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. (353 aa)
ASAC_0797Glutamyl-tRNA amidotransferase, subunit A. (398 aa)
ASAC_0752Putative translation factor (SUA5); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (361 aa)
ASAC_0706Hypothetical protein. (223 aa)
ASAC_0631N-terminal acetyltransferase. (165 aa)
ASAC_0034tRNA-splicing endonuclease subunit alpha. (187 aa)
ASAC_0077Probable tRNA pseudouridine synthase D. (370 aa)
ASAC_0094Predicted GTPase. (349 aa)
lysSlysyl-tRNA synthetase (LysS); Belongs to the class-II aminoacyl-tRNA synthetase family. (498 aa)
glySGlycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). (583 aa)
ASAC_0139Hypothetical protein. (80 aa)
ASAC_0140Translation initiation factor Sui1; Belongs to the SUI1 family. (101 aa)
ef1bElongation factor 1-beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (88 aa)
ASAC_0171Predicted fibronectin-binding protein. (647 aa)
pus10Predicted pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. (400 aa)
rpl14e50S ribosomal protein L14e; Belongs to the eukaryotic ribosomal protein eL14 family. (96 aa)
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (293 aa)
ASAC_0193Putative methyltransferase. (336 aa)
tbpTATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (207 aa)
rpl44e50S ribosomal protein L44E; Binds to the 23S rRNA. (95 aa)
nop10Nucleolar RNA-binding protein Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (57 aa)
ASAC_0203Translation initiation factor 2 subunit alpha. (269 aa)
ASAC_0213N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (388 aa)
ASAC_0215Hypothetical protein. (113 aa)
ASAC_0219Probable deoxyhypusine synthase. (319 aa)
rps830S ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa)
rps1430S ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (56 aa)
rpl550S ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (188 aa)
rps4e30S ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family. (250 aa)
rpl2450S ribosomal protein L24P; Located at the polypeptide exit tunnel on the outside of the subunit. (136 aa)
rpl1450S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (140 aa)
rps1730S ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (114 aa)
rnp1Ribonuclease P protein component 1, Rpp29; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family. (95 aa)
rpl2950S ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. (86 aa)
rps330S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (238 aa)
rpl2250S ribosomal protein L22P; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (159 aa)
rps19p30S ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (141 aa)
metGMethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily. (576 aa)
cysSCysteinyl-tRNA synthetase. (476 aa)
rpl1150S ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (169 aa)
alaSAlanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (913 aa)
rpl12Hypothetical protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (114 aa)
rpl10LSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (344 aa)
rpl150S ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (214 aa)
taw1tRNA-modifying enzyme; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (347 aa)
ASAC_0263Hypothetical protein. (270 aa)
eif2bTranslation initiation factor IF-2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (158 aa)
serSSeryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (459 aa)
ASAC_0276N-terminal acetyltransferase. (196 aa)
prf1Peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (403 aa)
ASAC_0285threonyl-tRNA synthetase. (467 aa)
ASAC_0287Valyl-tRNA synthetase. (821 aa)
ASAC_0292Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (177 aa)
tfeTranscription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing [...] (194 aa)
ASAC_0297Hypothetical protein. (203 aa)
ASAC_0306Hypothetical protein. (154 aa)
tgtA7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (515 aa)
ASAC_0309Like-Sm ribonucleoprotein, core. (149 aa)
rps17e30S ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family. (75 aa)
ASAC_0324Putative hydrogenase expression/formation protein HypE. (354 aa)
gltXGlutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (576 aa)
ASAC_0337phenylalanyl-tRNA synthetase subunit beta. (558 aa)
pheSphenylalanyl-tRNA synthetase subunit alpha; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (481 aa)
argSArginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (633 aa)
ileSIsoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1061 aa)
ASAC_0348Hypothetical protein. (329 aa)
ASAC_0365Threonyl/alanyl tRNA synthetase, SAD. (248 aa)
fusAElongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (731 aa)
proSProlyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (482 aa)
ASAC_0396Predicted methyltransferase. (351 aa)
ASAC_0400Hypothetical protein. (437 aa)
ASAC_0403Transcription elongation factor NusA-like protein. (196 aa)
ASAC_0410Asparaginyl-tRNA synthetase. (432 aa)
rpoKDNA-directed RNA polymerase subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (95 aa)
rpl21e50S ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. (99 aa)
ASAC_0429Signal peptidase. (178 aa)
ASAC_0444Putative ATPase RIL. (601 aa)
ASAC_0445rRNA methylase. (245 aa)
ASAC_0451Dimethyladenosine transferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (250 aa)
ASAC_0455Putative DNA-directed RNA polymerase subunit M; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (117 aa)
aspSAspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). (464 aa)
ASAC_0465Hypothetical protein. (101 aa)
gatAGlutamyl-tRNA(Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (479 aa)
gatBAspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (485 aa)
ASAC_0474Hypothetical protein; Belongs to the eukaryotic ribosomal protein eL38 family. (135 aa)
ASAC_0477tRNA (guanine-N1-)-methyltransferase. (354 aa)
ASAC_0502Putative translation initiation factor eIF-2B subunit; Belongs to the eIF-2B alpha/beta/delta subunits family. (294 aa)
trpSTryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (373 aa)
ASAC_0533Threonyl-tRNA synthetase. (468 aa)
ASAC_0547Hypothetical protein. (92 aa)
ASAC_0552Putative transcription initiation factor IIB. (303 aa)
ASAC_0566Putative small nucleolar RNP protein Sm. (92 aa)
ASAC_0589Putative protein kinase. (226 aa)
kae1Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family. (351 aa)
rps27ae30S ribosomal protein S27ae; Belongs to the eukaryotic ribosomal protein eS31 family. (60 aa)
rps24e30S ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. (127 aa)
ASAC_0599N-acetyltransferase. (189 aa)
thiIProbable thiamine biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (375 aa)
Your Current Organism:
Acidilobus saccharovorans
NCBI taxonomy Id: 666510
Other names: A. saccharovorans 345-15, Acidilobus saccharovorans 345-15, Acidilobus saccharovorans str. 345-15, Acidilobus saccharovorans strain 345-15, Acidilobus sp. 345-15
Server load: low (18%) [HD]