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| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (414 aa) |
| | ASAC_0029 | Fructose-1,6-bisphosphate aldolase. (288 aa) |
| | ASAC_0030 | ATP-dependent 6-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (320 aa) |
| | ASAC_0048 | NUDIX hydrolase. (171 aa) |
| | ASAC_0096 | Pyruvate:ferredoxin oxidoreductase (POR) and putative 2-oxoglutarate:ferredoxin oxidoreductase (KGOR), gamma subunitubunit. (192 aa) |
| | ASAC_0097 | Pyruvate:ferredoxin oxidoreductase (POR) and putative 2-oxoglutarate:ferredoxin oxidoreductase (KGOR), delta subunit. (112 aa) |
| | ASAC_0117 | Uridine phosphorylase. (281 aa) |
| | cmk | Cytidylate kinase, putative. (185 aa) |
| | ASAC_0155 | Acyl-CoA dehydrogenase. (399 aa) |
| | ASAC_0179 | Molybdopterin converting factor. (239 aa) |
| | ASAC_0188 | Nicotinamide-nucleotide adenylyltransferase. (177 aa) |
| | adkA | Adenylate kinase; Belongs to the archaeal adenylate kinase family. (209 aa) |
| | ASAC_0212 | Hypothetical protein. (199 aa) |
| | ASAC_0240 | Predicted dehydrogenase. (471 aa) |
| | ASAC_0267 | Electron transfer flavoprotein-quinone oxidoreductase. (434 aa) |
| | ASAC_0272 | DUF137 domain containing protein. (266 aa) |
| | ASAC_0273 | Hypothetical protein. (261 aa) |
| | nadE | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (278 aa) |
| | ASAC_0275 | Coenzyme A biosynthesis bifunctional protein CoaBC. (413 aa) |
| | ASAC_0280 | Nicotinamide-nucleotide adenylyltransferase. (170 aa) |
| | ASAC_0312 | Purine phosphoribosyltransferase. (251 aa) |
| | egsA | Glycerol-1-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. (353 aa) |
| | ASAC_0320 | Thioesterase. (329 aa) |
| | ASAC_0332 | Farnesylgeranyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (338 aa) |
| | ASAC_0336 | Hypothetical protein. (272 aa) |
| | dcd | Probable deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (183 aa) |
| | nadK | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (288 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (536 aa) |
| | atpE | V-type ATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane. (199 aa) |
| | atpA | V-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (601 aa) |
| | atpB | V-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (467 aa) |
| | ASAC_0421 | Probable uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (229 aa) |
| | ASAC_0468 | Type I phosphodiesterase/nucleotide pyrophosphatase. (383 aa) |
| | ASAC_0472 | Hit histidine triad protein. (179 aa) |
| | ASAC_0481 | Competence damage-inducible protein A. (271 aa) |
| | atpD | V-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (223 aa) |
| | ASAC_0485 | Inositol-1-monophosphatase. (264 aa) |
| | ASAC_0521 | HIT family protein. (162 aa) |
| | ASAC_0530 | DUF84 domain containing protein. (176 aa) |
| | ASAC_0539 | Acyl-CoA ligase (acyl-CoA synthetase). (639 aa) |
| | ASAC_0559 | CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (192 aa) |
| | ASAC_0565 | myo-Inositol-3-phosphate synthase. (383 aa) |
| | ASAC_0582 | Acyl-CoA dehydrogenase. (384 aa) |
| | ASAC_0588 | Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (185 aa) |
| | ASAC_0597 | Acyl-CoA ligase (acyl-CoA synthetase). (659 aa) |
| | ASAC_0610 | Indolepyruvate:ferredoxin oxidoreductase (IOR), beta subunit. (201 aa) |
| | thiI | Probable thiamine biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (375 aa) |
| | ASAC_0627 | Creatininase. (264 aa) |
| | rbsK | 2-Keto-3-deoxy-gluconate kinase (KDGK); Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (300 aa) |
| | ASAC_0727 | F420-0:gamma-glutamyl ligase. (296 aa) |
| | ASAC_0740 | Hypothetical protein. (93 aa) |
| | ASAC_0770 | Probable deoxyuridine 5'-triphosphate nucleotidohydrolase. (160 aa) |
| | ASAC_0782 | Probable (S)-2,3-Di-O-farnesylgeranylglyceryl synthase. (282 aa) |
| | ASAC_0809 | ATP-NAD/AcoX kinase. (364 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa) |
| | nnrE | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] (520 aa) |
| | ASAC_0852 | Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase). (225 aa) |
| | ASAC_0858 | Malate dehydrogenase. (473 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (517 aa) |
| | ASAC_0874 | Putative 2-oxoacid:ferredoxin oxidoreductase, beta subunit. (304 aa) |
| | ASAC_0875 | Putative 2-oxoacid:ferredoxin oxidoreductase, alpha subunit. (649 aa) |
| | ASAC_0878 | ADP-dependent hexokinase (HK). (328 aa) |
| | ASAC_0879 | Purine phosphoribosyltransferase. (232 aa) |
| | ASAC_0880 | Pyruvate kinase (PYK); Belongs to the pyruvate kinase family. (460 aa) |
| | ASAC_0891 | Phosphoglycerate kinase. (409 aa) |
| | gap | Glyceraldehyde-3-phosphate dehydrogenase (GAPDH). (348 aa) |
| | pyrD | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. (301 aa) |
| | ASAC_0968 | Dihydroorotase. (445 aa) |
| | pyrI | Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase. (157 aa) |
| | pyrB | Aspartate carbamoyltransferase. (314 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (200 aa) |
| | ASAC_0972 | Orotidine 5'-phosphate decarboxylase. (227 aa) |
| | ASAC_0991 | Metal-dependent hydrolase of the beta-lactamase superfamily. (234 aa) |
| | ASAC_0995 | Molybdopterin biosynthesis protein MogA. (158 aa) |
| | ASAC_0997 | Acyl-CoA ligase (acyl-CoA synthetase). (658 aa) |
| | moaA | Probable molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (370 aa) |
| | ribK | Hypothetical protein; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (152 aa) |
| | ASAC_1038 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. (419 aa) |
| | ASAC_1045 | Geranylgeranylglyceryl phosphate synthase-like protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (255 aa) |
| | ASAC_1046 | Nucleotide pyrophosphohydrolase. (94 aa) |
| | ASAC_1049 | Ribose-5-phosphate isomerase. (240 aa) |
| | ASAC_1055 | 2-Ketoisovalerate:ferredoxin oxidoreductase (VOR), delta subunit. (87 aa) |
| | ASAC_1056 | 2-Ketoisovalerate:ferredoxin oxidoreductase (VOR), gamma subunit. (183 aa) |
| | ASAC_1064 | Dehydrogenase (flavoprotein)-like protein. (356 aa) |
| | prs | Phosphoribosyl pyrophosphate synthase (PRPP synthase); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (294 aa) |
| | ASAC_1067 | Pur operon repressor-like protein. (220 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (141 aa) |
| | ASAC_1099 | Phosphoglycerate mutase (PGM). (427 aa) |
| | ASAC_1117 | Hypothetical protein. (281 aa) |
| | ASAC_1120 | Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (156 aa) |
| | thyX | Predicted alternative thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (333 aa) |
| | ASAC_1149 | Predicted hydrolase of the HD superfamily. (177 aa) |
| | ASAC_1158 | Nicotinic acid phosphoribosyltransferase, putative. (402 aa) |
| | ASAC_1200 | Molybdenum cofactor biosynthesis protein. (559 aa) |
| | ASAC_1206 | HD superfamily phosphohydrolase. (528 aa) |
| | ASAC_1212 | Adenylate cyclase. (179 aa) |
| | ASAC_1215 | DUF115 domain containing protein. (236 aa) |
| | ASAC_1216 | Molybdenum cofactor biosynthesis protein. (424 aa) |
| | carS | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. (167 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (225 aa) |
| | ASAC_1232 | Acyl-CoA dehydrogenase. (344 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (287 aa) |
| | ASAC_1244 | Putative 2-dehydropantoate 2-reductase. (308 aa) |
| | surE | 5'-nucleotidase surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (267 aa) |
| | ASAC_1260 | Acyl-CoA ligase (acyl-CoA synthetase). (656 aa) |
| | ASAC_1291 | Putative 2-oxoglutarate:ferredoxin oxidoreductase (KGOR), alpha subunit. (638 aa) |
| | ASAC_1292 | Putative 2-oxooglutarate:ferredoxin oxidoreductase (KGOR), beta subunit. (319 aa) |
| | ASAC_1319 | Dehydrogenase. (353 aa) |
| | ASAC_1326 | Probable molybdenum cofactor biosynthesis protein C. (143 aa) |
| | ASAC_1329 | Dehydrogenase (flavoprotein)-like protein. (386 aa) |
| | deoC | Probable deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (248 aa) |
| | tmk | Putative thymidylate kinase. (214 aa) |
| | ASAC_1398 | Probable molybdopterin-guanine dinucleotide biosynthesis protein A. (281 aa) |
| | ASAC_1430 | V-type ATP synthase subunit C. (342 aa) |
| | ASAC_1432 | Probable uracil phosphoribosyltransferase. (211 aa) |
| | mvk | Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (304 aa) |
| | ASAC_1492 | Hypothetical protein. (76 aa) |
| | ASAC_1493 | Creatinine amidohydrolase. (231 aa) |
| | gpmA | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (203 aa) |
