STRINGSTRING
thiI thiI ASAC_0793 ASAC_0793 ASAC_0816 ASAC_0816 ASAC_1053 ASAC_1053 ASAC_0874 ASAC_0874 ASAC_0875 ASAC_0875 ASAC_0963 ASAC_0963 mtnP mtnP ASAC_0997 ASAC_0997 ASAC_1260 ASAC_1260 ASAC_1232 ASAC_1232 ASAC_1215 ASAC_1215 sat sat cysC cysC ASAC_0096 ASAC_0096 ASAC_0097 ASAC_0097 ASAC_0098 ASAC_0098 ASAC_0099 ASAC_0099 ASAC_0155 ASAC_0155 mat mat ASAC_1056 ASAC_1056 ASAC_1055 ASAC_1055 ASAC_1054 ASAC_1054 thiL thiL metE metE ASAC_0539 ASAC_0539 ASAC_0582 ASAC_0582 ASAC_0597 ASAC_0597 ASAC_0610 ASAC_0610 ASAC_0611 ASAC_0611 ASAC_1292 ASAC_1292 ASAC_1291 ASAC_1291 ASAC_1274 ASAC_1274
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
thiIProbable thiamine biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (375 aa)
ASAC_0793Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (386 aa)
ASAC_0816Putative translation initiation factor eIF-2B subunit 1; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. (367 aa)
ASAC_10532-Ketoisovalerate:ferredoxin oxidoreductase (VOR), beta subunit. (305 aa)
ASAC_0874Putative 2-oxoacid:ferredoxin oxidoreductase, beta subunit. (304 aa)
ASAC_0875Putative 2-oxoacid:ferredoxin oxidoreductase, alpha subunit. (649 aa)
ASAC_0963Hypothetical protein. (189 aa)
mtnP5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (282 aa)
ASAC_0997Acyl-CoA ligase (acyl-CoA synthetase). (658 aa)
ASAC_1260Acyl-CoA ligase (acyl-CoA synthetase). (656 aa)
ASAC_1232Acyl-CoA dehydrogenase. (344 aa)
ASAC_1215DUF115 domain containing protein. (236 aa)
satSulfate adenylyltransferase; Belongs to the sulfate adenylyltransferase family. (390 aa)
cysCAdenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (180 aa)
ASAC_0096Pyruvate:ferredoxin oxidoreductase (POR) and putative 2-oxoglutarate:ferredoxin oxidoreductase (KGOR), gamma subunitubunit. (192 aa)
ASAC_0097Pyruvate:ferredoxin oxidoreductase (POR) and putative 2-oxoglutarate:ferredoxin oxidoreductase (KGOR), delta subunit. (112 aa)
ASAC_0098Pyruvate:ferredoxin oxidoreductase (POR), alpha subunit. (397 aa)
ASAC_0099Pyruvate:ferredoxin oxidoreductase (POR), beta subunit. (324 aa)
ASAC_0155Acyl-CoA dehydrogenase. (399 aa)
matS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (406 aa)
ASAC_10562-Ketoisovalerate:ferredoxin oxidoreductase (VOR), gamma subunit. (183 aa)
ASAC_10552-Ketoisovalerate:ferredoxin oxidoreductase (VOR), delta subunit. (87 aa)
ASAC_10542-Ketoisovalerate:ferredoxin oxidoreductase (VOR), alpha subunit. (400 aa)
thiLPutative thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (293 aa)
metEProbable methylcobalamin:homocysteine methyltransferase; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown. (330 aa)
ASAC_0539Acyl-CoA ligase (acyl-CoA synthetase). (639 aa)
ASAC_0582Acyl-CoA dehydrogenase. (384 aa)
ASAC_0597Acyl-CoA ligase (acyl-CoA synthetase). (659 aa)
ASAC_0610Indolepyruvate:ferredoxin oxidoreductase (IOR), beta subunit. (201 aa)
ASAC_0611Indolepyruvate:ferredoxin oxidoreductase (IOR), alpha subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (633 aa)
ASAC_1292Putative 2-oxooglutarate:ferredoxin oxidoreductase (KGOR), beta subunit. (319 aa)
ASAC_1291Putative 2-oxoglutarate:ferredoxin oxidoreductase (KGOR), alpha subunit. (638 aa)
ASAC_1274Phosphomethylpyrimidine kinase. (462 aa)
Your Current Organism:
Acidilobus saccharovorans
NCBI taxonomy Id: 666510
Other names: A. saccharovorans 345-15, Acidilobus saccharovorans 345-15, Acidilobus saccharovorans str. 345-15, Acidilobus saccharovorans strain 345-15, Acidilobus sp. 345-15
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.