STRINGSTRING
ASAC_1492 ASAC_1492 ASAC_0096 ASAC_0096 ASAC_1045 ASAC_1045 ASAC_0097 ASAC_0097 ASAC_0117 ASAC_0117 cmk cmk ASAC_0155 ASAC_0155 ASAC_0179 ASAC_0179 ASAC_0188 ASAC_0188 adkA adkA ASAC_0212 ASAC_0212 ASAC_0240 ASAC_0240 ASAC_0267 ASAC_0267 ASAC_0272 ASAC_0272 ASAC_0273 ASAC_0273 nadE nadE ASAC_0275 ASAC_0275 ASAC_0280 ASAC_0280 ASAC_0312 ASAC_0312 egsA egsA ASAC_0332 ASAC_0332 ASAC_0336 ASAC_0336 dcd dcd nadK nadK pyrG pyrG atpE atpE atpA atpA atpB atpB ASAC_0421 ASAC_0421 ASAC_0481 ASAC_0481 atpD atpD ASAC_0539 ASAC_0539 ASAC_0559 ASAC_0559 ASAC_0565 ASAC_0565 ASAC_0582 ASAC_0582 ASAC_0597 ASAC_0597 ASAC_0610 ASAC_0610 thiI thiI ASAC_0740 ASAC_0740 ASAC_0770 ASAC_0770 ASAC_0782 ASAC_0782 ASAC_0809 ASAC_0809 ASAC_0858 ASAC_0858 guaA guaA ASAC_0874 ASAC_0874 ASAC_0875 ASAC_0875 ASAC_0879 ASAC_0879 pyrD pyrD ASAC_0968 ASAC_0968 pyrI pyrI pyrB pyrB pyrE pyrE ASAC_0972 ASAC_0972 ASAC_0991 ASAC_0991 ASAC_0995 ASAC_0995 ASAC_0997 ASAC_0997 moaA moaA ribK ribK ASAC_1055 ASAC_1055 ASAC_1056 ASAC_1056 ASAC_1064 ASAC_1064 prs prs ASAC_1067 ASAC_1067 ndk ndk ASAC_1117 ASAC_1117 ASAC_1120 ASAC_1120 thyX thyX ASAC_1158 ASAC_1158 ASAC_1200 ASAC_1200 ASAC_1212 ASAC_1212 ASAC_1215 ASAC_1215 ASAC_1216 ASAC_1216 carS carS ASAC_1232 ASAC_1232 panB panB ASAC_1244 ASAC_1244 ASAC_1260 ASAC_1260 ASAC_1291 ASAC_1291 ASAC_1292 ASAC_1292 ASAC_1319 ASAC_1319 ASAC_1326 ASAC_1326 ASAC_1329 ASAC_1329 tmk tmk ASAC_1398 ASAC_1398 ASAC_1430 ASAC_1430 ASAC_1432 ASAC_1432 mvk mvk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ASAC_1492Hypothetical protein. (76 aa)
ASAC_0096Pyruvate:ferredoxin oxidoreductase (POR) and putative 2-oxoglutarate:ferredoxin oxidoreductase (KGOR), gamma subunitubunit. (192 aa)
ASAC_1045Geranylgeranylglyceryl phosphate synthase-like protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (255 aa)
ASAC_0097Pyruvate:ferredoxin oxidoreductase (POR) and putative 2-oxoglutarate:ferredoxin oxidoreductase (KGOR), delta subunit. (112 aa)
ASAC_0117Uridine phosphorylase. (281 aa)
cmkCytidylate kinase, putative. (185 aa)
ASAC_0155Acyl-CoA dehydrogenase. (399 aa)
ASAC_0179Molybdopterin converting factor. (239 aa)
ASAC_0188Nicotinamide-nucleotide adenylyltransferase. (177 aa)
adkAAdenylate kinase; Belongs to the archaeal adenylate kinase family. (209 aa)
ASAC_0212Hypothetical protein. (199 aa)
ASAC_0240Predicted dehydrogenase. (471 aa)
ASAC_0267Electron transfer flavoprotein-quinone oxidoreductase. (434 aa)
ASAC_0272DUF137 domain containing protein. (266 aa)
ASAC_0273Hypothetical protein. (261 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (278 aa)
ASAC_0275Coenzyme A biosynthesis bifunctional protein CoaBC. (413 aa)
ASAC_0280Nicotinamide-nucleotide adenylyltransferase. (170 aa)
ASAC_0312Purine phosphoribosyltransferase. (251 aa)
egsAGlycerol-1-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. (353 aa)
ASAC_0332Farnesylgeranyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (338 aa)
ASAC_0336Hypothetical protein. (272 aa)
dcdProbable deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (183 aa)
nadKInorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (288 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (536 aa)
atpEV-type ATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane. (199 aa)
atpAV-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (601 aa)
atpBV-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (467 aa)
ASAC_0421Probable uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (229 aa)
ASAC_0481Competence damage-inducible protein A. (271 aa)
atpDV-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (223 aa)
ASAC_0539Acyl-CoA ligase (acyl-CoA synthetase). (639 aa)
ASAC_0559CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (192 aa)
ASAC_0565myo-Inositol-3-phosphate synthase. (383 aa)
ASAC_0582Acyl-CoA dehydrogenase. (384 aa)
ASAC_0597Acyl-CoA ligase (acyl-CoA synthetase). (659 aa)
ASAC_0610Indolepyruvate:ferredoxin oxidoreductase (IOR), beta subunit. (201 aa)
thiIProbable thiamine biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (375 aa)
ASAC_0740Hypothetical protein. (93 aa)
ASAC_0770Probable deoxyuridine 5'-triphosphate nucleotidohydrolase. (160 aa)
ASAC_0782Probable (S)-2,3-Di-O-farnesylgeranylglyceryl synthase. (282 aa)
ASAC_0809ATP-NAD/AcoX kinase. (364 aa)
ASAC_0858Malate dehydrogenase. (473 aa)
guaAGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (517 aa)
ASAC_0874Putative 2-oxoacid:ferredoxin oxidoreductase, beta subunit. (304 aa)
ASAC_0875Putative 2-oxoacid:ferredoxin oxidoreductase, alpha subunit. (649 aa)
ASAC_0879Purine phosphoribosyltransferase. (232 aa)
pyrDDihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. (301 aa)
ASAC_0968Dihydroorotase. (445 aa)
pyrIAspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase. (157 aa)
pyrBAspartate carbamoyltransferase. (314 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (200 aa)
ASAC_0972Orotidine 5'-phosphate decarboxylase. (227 aa)
ASAC_0991Metal-dependent hydrolase of the beta-lactamase superfamily. (234 aa)
ASAC_0995Molybdopterin biosynthesis protein MogA. (158 aa)
ASAC_0997Acyl-CoA ligase (acyl-CoA synthetase). (658 aa)
moaAProbable molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (370 aa)
ribKHypothetical protein; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (152 aa)
ASAC_10552-Ketoisovalerate:ferredoxin oxidoreductase (VOR), delta subunit. (87 aa)
ASAC_10562-Ketoisovalerate:ferredoxin oxidoreductase (VOR), gamma subunit. (183 aa)
ASAC_1064Dehydrogenase (flavoprotein)-like protein. (356 aa)
prsPhosphoribosyl pyrophosphate synthase (PRPP synthase); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (294 aa)
ASAC_1067Pur operon repressor-like protein. (220 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (141 aa)
ASAC_1117Hypothetical protein. (281 aa)
ASAC_1120Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (156 aa)
thyXPredicted alternative thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (333 aa)
ASAC_1158Nicotinic acid phosphoribosyltransferase, putative. (402 aa)
ASAC_1200Molybdenum cofactor biosynthesis protein. (559 aa)
ASAC_1212Adenylate cyclase. (179 aa)
ASAC_1215DUF115 domain containing protein. (236 aa)
ASAC_1216Molybdenum cofactor biosynthesis protein. (424 aa)
carSHypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. (167 aa)
ASAC_1232Acyl-CoA dehydrogenase. (344 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (287 aa)
ASAC_1244Putative 2-dehydropantoate 2-reductase. (308 aa)
ASAC_1260Acyl-CoA ligase (acyl-CoA synthetase). (656 aa)
ASAC_1291Putative 2-oxoglutarate:ferredoxin oxidoreductase (KGOR), alpha subunit. (638 aa)
ASAC_1292Putative 2-oxooglutarate:ferredoxin oxidoreductase (KGOR), beta subunit. (319 aa)
ASAC_1319Dehydrogenase. (353 aa)
ASAC_1326Probable molybdenum cofactor biosynthesis protein C. (143 aa)
ASAC_1329Dehydrogenase (flavoprotein)-like protein. (386 aa)
tmkPutative thymidylate kinase. (214 aa)
ASAC_1398Probable molybdopterin-guanine dinucleotide biosynthesis protein A. (281 aa)
ASAC_1430V-type ATP synthase subunit C. (342 aa)
ASAC_1432Probable uracil phosphoribosyltransferase. (211 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (304 aa)
Your Current Organism:
Acidilobus saccharovorans
NCBI taxonomy Id: 666510
Other names: A. saccharovorans 345-15, Acidilobus saccharovorans 345-15, Acidilobus saccharovorans str. 345-15, Acidilobus saccharovorans strain 345-15, Acidilobus sp. 345-15
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