STRINGSTRING
ASAC_1221 ASAC_1221 ASAC_0065 ASAC_0065 ASAC_0078 ASAC_0078 ASAC_0082 ASAC_0082 cobB cobB albA albA priS priS rpl44e rpl44e nop10 nop10 top6A top6A rps4e rps4e rps17 rps17 rpl29 rpl29 rps3 rps3 rps19p rps19p rpl12 rpl12 rpl10 rpl10 rps17e rps17e ASAC_0343 ASAC_0343 ASAC_0385 ASAC_0385 rpl21e rpl21e ASAC_0506 ASAC_0506 ASAC_0551 ASAC_0551 ASAC_0553 ASAC_0553 rps24e rps24e ASAC_0642 ASAC_0642 ASAC_0690 ASAC_0690 ASAC_0709 ASAC_0709 ASAC_0749 ASAC_0749 rfcS rfcS rfcL rfcL ASAC_0957 ASAC_0957 ASAC_0958 ASAC_0958 ASAC_0963 ASAC_0963 ASAC_1000 ASAC_1000 rps2 rps2 rps9 rps9 rps4 rps4 priL priL ASAC_1052 ASAC_1052 rps28e rps28e rps3ae rps3ae rpl40e rpl40e ASAC_1110 ASAC_1110 ASAC_1128 ASAC_1128 rpl15e rpl15e rpl37ae rpl37ae rpl24e rpl24e rpl30e rpl30e rps10 rps10 ASAC_1188 ASAC_1188 ASAC_1206 ASAC_1206 ASAC_1212 ASAC_1212 rps19e rps19e rpl6 rpl6 rpl19e rpl19e rpl18 rpl18 rps5 rps5 ASAC_1241 ASAC_1241 ASAC_1245 ASAC_1245 ASAC_1305 ASAC_1305 ASAC_1313 ASAC_1313 flpA flpA ASAC_1322 ASAC_1322 ASAC_1324 ASAC_1324 dnaG dnaG nep1 nep1 albA-2 albA-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ASAC_122150S ribosomal protein L32e. (135 aa)
ASAC_0065Glycosyl transferase, family 2. (424 aa)
ASAC_0078Glycosyl transferase, putative. (363 aa)
ASAC_0082MoxR-like ATPase. (307 aa)
cobBNAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily. (264 aa)
albADNA/RNA-binding protein Alba 2; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family. (99 aa)
priSProbable DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer sy [...] (357 aa)
rpl44e50S ribosomal protein L44E; Binds to the 23S rRNA. (95 aa)
nop10Nucleolar RNA-binding protein Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (57 aa)
top6AType II DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (387 aa)
rps4e30S ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family. (250 aa)
rps1730S ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (114 aa)
rpl2950S ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. (86 aa)
rps330S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (238 aa)
rps19p30S ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (141 aa)
rpl12Hypothetical protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (114 aa)
rpl10LSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (344 aa)
rps17e30S ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family. (75 aa)
ASAC_0343Predicted ATPase. (320 aa)
ASAC_0385Hypothetical protein. (338 aa)
rpl21e50S ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. (99 aa)
ASAC_0506Sugar-specific transcriptional regulator, TrmB family. (245 aa)
ASAC_0551ATP-dependent helicase. (1343 aa)
ASAC_0553Hypothetical protein. (94 aa)
rps24e30S ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. (127 aa)
ASAC_0642ATPase. (318 aa)
ASAC_0690ATPase. (405 aa)
ASAC_0709Linocin_M18 bacteriocin protein. (351 aa)
ASAC_0749Origin recognition complex subunit 1 Orc1; Involved in regulation of DNA replication. (417 aa)
rfcSReplication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (329 aa)
rfcLReplication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (484 aa)
ASAC_0957DNA double-strand break repair rad50 ATPase. (912 aa)
ASAC_0958DNA double-strand break repair protein mre11. (410 aa)
ASAC_0963Hypothetical protein. (189 aa)
ASAC_1000Hypothetical protein. (112 aa)
rps230S ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (239 aa)
rps930S ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (167 aa)
rps430S ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (177 aa)
priLDNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (341 aa)
ASAC_1052MoxR-like ATPase. (383 aa)
rps28e30S ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family. (83 aa)
rps3ae30S ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. (223 aa)
rpl40e50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. (57 aa)
ASAC_111030S ribosomal protein S26e. (95 aa)
ASAC_1128Hypothetical protein. (78 aa)
rpl15e50S ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family. (227 aa)
rpl37ae50S ribosomal protein L37Ae; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily. (82 aa)
rpl24e50S ribosomal protein L24e; Binds to the 23S rRNA. (63 aa)
rpl30e50S ribosomal protein L30e; Belongs to the eukaryotic ribosomal protein eL30 family. (104 aa)
rps1030S ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa)
ASAC_1188Hypothetical protein. (277 aa)
ASAC_1206HD superfamily phosphohydrolase. (528 aa)
ASAC_1212Adenylate cyclase. (179 aa)
rps19e30S ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (151 aa)
rpl650S ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (182 aa)
rpl19e50S ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (156 aa)
rpl1850S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (212 aa)
rps530S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (199 aa)
ASAC_1241Sugar-specific transcriptional regulator, TrmB family. (241 aa)
ASAC_1245Hypothetical protein. (88 aa)
ASAC_1305Putative GTP-binding protein. (338 aa)
ASAC_1313SnoRNA binding protein. (417 aa)
flpAFibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (219 aa)
ASAC_1322Predicted EndoIII-related endonuclease. (230 aa)
ASAC_1324Origin recognition complex subunit 2 Orc2; Involved in regulation of DNA replication. (412 aa)
dnaGHypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (439 aa)
nep1Probable ribosome biogenesis protein NEP1-like protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. (215 aa)
albA-2DNA/RNA-binding protein Alba 1; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family. (108 aa)
Your Current Organism:
Acidilobus saccharovorans
NCBI taxonomy Id: 666510
Other names: A. saccharovorans 345-15, Acidilobus saccharovorans 345-15, Acidilobus saccharovorans str. 345-15, Acidilobus saccharovorans strain 345-15, Acidilobus sp. 345-15
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.