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M301_0605 M301_0605 M301_0686 M301_0686 M301_0687 M301_0687 prpB prpB M301_0694 M301_0694 M301_0695 M301_0695 M301_0696 M301_0696 M301_0697 M301_0697 M301_0701 M301_0701 M301_0703 M301_0703 sucC sucC sucD sucD
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
M301_0605KEGG: mmb:Mmol_0597 isocitrate dehydrogenase (NADP(+)); PFAM: isocitrate/isopropylmalate dehydrogenase. (418 aa)
M301_0686TIGRFAM: 2-methylcitrate dehydratase; KEGG: mmb:Mmol_0748 2-methylcitrate dehydratase; PFAM: MmgE/PrpD family protein. (486 aa)
M301_0687TIGRFAM: 2-methylcitrate synthase/citrate synthase II; KEGG: mmb:Mmol_0749 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family. (391 aa)
prpBMethylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (295 aa)
M301_0694KEGG: mmb:Mmol_0757 succinate dehydrogenase, cytochrome b556 subunit; TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit. (141 aa)
M301_0695TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; KEGG: mmb:Mmol_0758 succinate dehydrogenase, hydrophobic membrane anchor protein. (114 aa)
M301_0696KEGG: mmb:Mmol_0759 succinate dehydrogenase or fumarate reductase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (587 aa)
M301_0697TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: mmb:Mmol_0760 succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (246 aa)
M301_0701Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (509 aa)
M301_0703KEGG: mmb:Mmol_0766 aconitate hydratase 2; TIGRFAM: aconitate hydratase 2; PFAM: Aconitase B; aconitate hydratase domain protein; Belongs to the aconitase/IPM isomerase family. (862 aa)
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (387 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa)
Your Current Organism:
Methylotenera versatilis 301
NCBI taxonomy Id: 666681
Other names: M. versatilis 301, Methylotenera sp. 301, Methylotenera versatilis str. 301, Methylotenera versatilis strain 301
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