(5 nodes) JUN phosphorylation, and JUN kinase kinase activity network (Daphnia pulex)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	E9FWB6_DAPPU	Protein kinase domain-containing protein. (313 aa)
	E9GA50_DAPPU	Mitogen-activated protein kinase. (380 aa)
	E9GA52_DAPPU	Mitogen-activated protein kinase. (378 aa)
	E9GVL4_DAPPU	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (388 aa)
	E9H6G6_DAPPU	Uncharacterized protein. (190 aa)

Your Current Organism:

Daphnia pulex

NCBI taxonomy Id: 6669
Other names: D. pulex, common water flea

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E9FWB6_DAPPU	E9GA50_DAPPU	E9FWB6	E9GA50	Protein kinase domain-containing protein.	Mitogen-activated protein kinase.	0.994
E9FWB6_DAPPU	E9GA52_DAPPU	E9FWB6	E9GA52	Protein kinase domain-containing protein.	Mitogen-activated protein kinase.	0.994
E9FWB6_DAPPU	E9GVL4_DAPPU	E9FWB6	E9GVL4	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.693
E9GA50_DAPPU	E9FWB6_DAPPU	E9GA50	E9FWB6	Mitogen-activated protein kinase.	Protein kinase domain-containing protein.	0.994
E9GA50_DAPPU	E9GA52_DAPPU	E9GA50	E9GA52	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.900
E9GA50_DAPPU	E9GVL4_DAPPU	E9GA50	E9GVL4	Mitogen-activated protein kinase.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.903
E9GA50_DAPPU	E9H6G6_DAPPU	E9GA50	E9H6G6	Mitogen-activated protein kinase.	Uncharacterized protein.	0.951
E9GA52_DAPPU	E9FWB6_DAPPU	E9GA52	E9FWB6	Mitogen-activated protein kinase.	Protein kinase domain-containing protein.	0.994
E9GA52_DAPPU	E9GA50_DAPPU	E9GA52	E9GA50	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.900
E9GA52_DAPPU	E9GVL4_DAPPU	E9GA52	E9GVL4	Mitogen-activated protein kinase.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.904
E9GA52_DAPPU	E9H6G6_DAPPU	E9GA52	E9H6G6	Mitogen-activated protein kinase.	Uncharacterized protein.	0.951
E9GVL4_DAPPU	E9FWB6_DAPPU	E9GVL4	E9FWB6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.693
E9GVL4_DAPPU	E9GA50_DAPPU	E9GVL4	E9GA50	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.903
E9GVL4_DAPPU	E9GA52_DAPPU	E9GVL4	E9GA52	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.904
E9H6G6_DAPPU	E9GA50_DAPPU	E9H6G6	E9GA50	Uncharacterized protein.	Mitogen-activated protein kinase.	0.951
E9H6G6_DAPPU	E9GA52_DAPPU	E9H6G6	E9GA52	Uncharacterized protein.	Mitogen-activated protein kinase.	0.951