(63 nodes) Regulation of phosphatidylinositol 3-kinase signaling network (Daphnia pulex)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	E9H4M3_DAPPU	Protein kinase domain-containing protein. (78 aa)
	E9H4U6_DAPPU	Uncharacterized protein. (549 aa)
	E9H4Z3_DAPPU	Protein kinase domain-containing protein. (300 aa)
	E9H509_DAPPU	Protein kinase domain-containing protein. (76 aa)
	E9H5G0_DAPPU	Protein kinase domain-containing protein. (453 aa)
	E9H5G1_DAPPU	Protein kinase domain-containing protein. (702 aa)
	E9H5G3_DAPPU	Uncharacterized protein. (731 aa)
	E9H5I9_DAPPU	Receptor protein-tyrosine kinase. (531 aa)
	E9H5J0_DAPPU	Protein kinase domain-containing protein. (338 aa)
	E9H5T6_DAPPU	Protein kinase domain-containing protein. (377 aa)
	E9H5T9_DAPPU	Protein kinase domain-containing protein. (382 aa)
	E9H681_DAPPU	Tyrosine-protein kinase receptor. (313 aa)
	E9H8V5_DAPPU	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (334 aa)
	E9H9C6_DAPPU	Protein kinase domain-containing protein. (78 aa)
	E9HA61_DAPPU	PIP49_C domain-containing protein. (435 aa)
	E9HBG6_DAPPU	Uncharacterized protein. (923 aa)
	E9HBG9_DAPPU	Uncharacterized protein. (773 aa)
	E9HD20_DAPPU	Protein kinase domain-containing protein. (355 aa)
	E9HGG1_DAPPU	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (373 aa)
	E9HGG2_DAPPU	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (328 aa)
	E9HGR9_DAPPU	Pkinase_Tyr domain-containing protein. (89 aa)
	E9HGU7_DAPPU	Protein kinase domain-containing protein. (156 aa)
	E9HHQ5_DAPPU	Protein kinase domain-containing protein. (419 aa)
	E9HHS9_DAPPU	Tyrosine-protein kinase receptor. (885 aa)
	E9HHV1_DAPPU	Tyrosine-protein kinase receptor. (593 aa)
	E9HJ65_DAPPU	Uncharacterized protein. (303 aa)
	E9HLZ6_DAPPU	Receptor protein-tyrosine kinase. (1468 aa)
	E9HNF0_DAPPU	Protein kinase domain-containing protein. (423 aa)
	E9HNF3_DAPPU	Protein kinase domain-containing protein. (427 aa)
	E9HNF4_DAPPU	Protein kinase domain-containing protein. (419 aa)
	E9HSM1_DAPPU	Protein kinase domain-containing protein. (103 aa)
	E9HUG5_DAPPU	Protein kinase domain-containing protein. (56 aa)
	E9HUG6_DAPPU	Protein kinase domain-containing protein. (176 aa)
	E9G1G8_DAPPU	Uncharacterized protein. (279 aa)
	E9FZF2_DAPPU	Protein kinase domain-containing protein. (365 aa)
	E9FZC2_DAPPU	Protein kinase domain-containing protein. (96 aa)
	E9FZC1_DAPPU	Protein kinase domain-containing protein. (125 aa)
	E9FZB6_DAPPU	Protein kinase domain-containing protein. (426 aa)
	E9FUV7_DAPPU	Uncharacterized protein. (353 aa)
	E9HR67_DAPPU	SH2 domain-containing protein. (223 aa)
	E9HZE7_DAPPU	Protein kinase domain-containing protein. (288 aa)
	E9HZQ7_DAPPU	Protein kinase domain-containing protein. (296 aa)
	E9G5E4_DAPPU	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (307 aa)
	E9G5X5_DAPPU	Uncharacterized protein. (2067 aa)
	E9G9M0_DAPPU	Uncharacterized protein. (3407 aa)
	E9GCS3_DAPPU	Protein kinase domain-containing protein. (317 aa)
	E9GD15_DAPPU	Protein kinase domain-containing protein. (311 aa)
	E9GET2_DAPPU	Protein kinase domain-containing protein. (762 aa)
	E9GFW2_DAPPU	Phosphatase and tensin-like protein. (280 aa)
	E9GJC5_DAPPU	Protein kinase domain-containing protein. (120 aa)
	E9GJC6_DAPPU	Protein kinase domain-containing protein. (146 aa)
	E9GLG7_DAPPU	Putative insulin receptor substrate. (202 aa)
	E9GQ40_DAPPU	Protein kinase domain-containing protein. (442 aa)
	E9GQD0_DAPPU	Protein kinase domain-containing protein. (516 aa)
	E9GU44_DAPPU	LNS2 domain-containing protein. (1037 aa)
	E9H017_DAPPU	Protein kinase domain-containing protein. (55 aa)
	E9H018_DAPPU	Protein kinase domain-containing protein. (322 aa)
	E9H1Y8_DAPPU	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
	E9H1Z0_DAPPU	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (326 aa)
	E9H1Z1_DAPPU	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa)
	E9H1Z7_DAPPU	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (320 aa)
	E9H207_DAPPU	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (313 aa)
	E9H4E6_DAPPU	PIPK domain-containing protein. (426 aa)

Your Current Organism:

Daphnia pulex

NCBI taxonomy Id: 6669
Other names: D. pulex, common water flea

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E9G5X5_DAPPU	E9GET2_DAPPU	E9G5X5	E9GET2	Uncharacterized protein.	Protein kinase domain-containing protein.	0.997
E9GET2_DAPPU	E9G5X5_DAPPU	E9GET2	E9G5X5	Protein kinase domain-containing protein.	Uncharacterized protein.	0.997
E9GFW2_DAPPU	E9GLG7_DAPPU	E9GFW2	E9GLG7	Phosphatase and tensin-like protein.	Putative insulin receptor substrate.	0.439
E9GFW2_DAPPU	E9H4E6_DAPPU	E9GFW2	E9H4E6	Phosphatase and tensin-like protein.	PIPK domain-containing protein.	0.911
E9GLG7_DAPPU	E9GFW2_DAPPU	E9GLG7	E9GFW2	Putative insulin receptor substrate.	Phosphatase and tensin-like protein.	0.439
E9GLG7_DAPPU	E9H681_DAPPU	E9GLG7	E9H681	Putative insulin receptor substrate.	Tyrosine-protein kinase receptor.	0.681
E9GLG7_DAPPU	E9HR67_DAPPU	E9GLG7	E9HR67	Putative insulin receptor substrate.	SH2 domain-containing protein.	0.790
E9H017_DAPPU	E9H9C6_DAPPU	E9H017	E9H9C6	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.451
E9H4E6_DAPPU	E9GFW2_DAPPU	E9H4E6	E9GFW2	PIPK domain-containing protein.	Phosphatase and tensin-like protein.	0.911
E9H681_DAPPU	E9GLG7_DAPPU	E9H681	E9GLG7	Tyrosine-protein kinase receptor.	Putative insulin receptor substrate.	0.681
E9H9C6_DAPPU	E9H017_DAPPU	E9H9C6	E9H017	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.451
E9H9C6_DAPPU	E9HUG5_DAPPU	E9H9C6	E9HUG5	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.446
E9HHS9_DAPPU	E9HHV1_DAPPU	E9HHS9	E9HHV1	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.900
E9HHV1_DAPPU	E9HHS9_DAPPU	E9HHV1	E9HHS9	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.900
E9HR67_DAPPU	E9GLG7_DAPPU	E9HR67	E9GLG7	SH2 domain-containing protein.	Putative insulin receptor substrate.	0.790
E9HUG5_DAPPU	E9H9C6_DAPPU	E9HUG5	E9H9C6	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.446