(4 nodes) Sin3 complex network (Daphnia pulex)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	E9GU16_DAPPU	Uncharacterized protein. (259 aa)
	RPD3	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (538 aa)
	E9H6T4_DAPPU	HDAC_interact domain-containing protein. (1217 aa)
	E9HMZ8_DAPPU	Uncharacterized protein. (50 aa)

Your Current Organism:

Daphnia pulex

NCBI taxonomy Id: 6669
Other names: D. pulex, common water flea

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E9GU16_DAPPU	E9H6T4_DAPPU	E9GU16	E9H6T4	Uncharacterized protein.	HDAC_interact domain-containing protein.	0.811
E9H6T4_DAPPU	E9GU16_DAPPU	E9H6T4	E9GU16	HDAC_interact domain-containing protein.	Uncharacterized protein.	0.811
E9H6T4_DAPPU	E9HMZ8_DAPPU	E9H6T4	E9HMZ8	HDAC_interact domain-containing protein.	Uncharacterized protein.	0.956
E9H6T4_DAPPU	RPD3	E9H6T4	E9GZX2	HDAC_interact domain-containing protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.956
E9HMZ8_DAPPU	E9H6T4_DAPPU	E9HMZ8	E9H6T4	Uncharacterized protein.	HDAC_interact domain-containing protein.	0.956
RPD3	E9H6T4_DAPPU	E9GZX2	E9H6T4	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	HDAC_interact domain-containing protein.	0.956