(58 nodes) Negative regulation of hippo signaling network (Daphnia pulex)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EOG090X060Z	EOG090X060Z. (348 aa)
	E9HI82_DAPPU	Uncharacterized protein. (933 aa)
	E9HJU7_DAPPU	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2009 aa)
	E9HLB4_DAPPU	Uncharacterized protein. (519 aa)
	E9HLB5_DAPPU	Uncharacterized protein. (510 aa)
	E9HLC0_DAPPU	Uncharacterized protein. (513 aa)
	E9HMX3_DAPPU	Uncharacterized protein. (510 aa)
	E9HND3_DAPPU	Uncharacterized protein. (432 aa)
	E9HNI5_DAPPU	Uncharacterized protein. (185 aa)
	E9HWZ2_DAPPU	Uncharacterized protein. (727 aa)
	E9HX25_DAPPU	F-box domain-containing protein. (311 aa)
	E9HY31_DAPPU	Uncharacterized protein. (1354 aa)
	E9I0K3_DAPPU	F-box domain-containing protein. (156 aa)
	E9I0W3_DAPPU	Serine/threonine-protein phosphatase. (201 aa)
	E9GGX2_DAPPU	Uncharacterized protein. (2026 aa)
	E9FRE5_DAPPU	TOG domain-containing protein. (590 aa)
	EOG090X0BA8	EOG090X0BA8. (227 aa)
	DAPPUDRAFT_6	Uncharacterized protein. (3261 aa)
	E9FSB4_DAPPU	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (347 aa)
	E9FT39_DAPPU	Uncharacterized protein. (1570 aa)
	E9FTF6_DAPPU	F-box domain-containing protein. (186 aa)
	E9FU96_DAPPU	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1013 aa)
	E9FVU3_DAPPU	Uncharacterized protein. (1188 aa)
	E9FVU5_DAPPU	Protein kinase domain-containing protein. (289 aa)
	E9FWF3_DAPPU	Uncharacterized protein. (490 aa)
	E9G0N3_DAPPU	Uncharacterized protein. (548 aa)
	E9G2F4_DAPPU	WD_REPEATS_REGION domain-containing protein. (684 aa)
	E9G2M5_DAPPU	Non-specific serine/threonine protein kinase. (532 aa)
	E9G331_DAPPU	Non-specific serine/threonine protein kinase. (833 aa)
	E9G447_DAPPU	HECT domain-containing protein. (1052 aa)
	E9G584_DAPPU	MYND-type domain-containing protein. (498 aa)
	E9G585_DAPPU	Uncharacterized protein. (489 aa)
	E9G588_DAPPU	Uncharacterized protein. (387 aa)
	DAPPUDRAFT_915	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (498 aa)
	E9GDU7_DAPPU	F-box domain-containing protein. (487 aa)
	E9GEM8_DAPPU	Uncharacterized protein. (805 aa)
	E9GFD9_DAPPU	Uncharacterized protein. (175 aa)
	E9GFR4_DAPPU	Uncharacterized protein. (741 aa)
	E9GIQ7_DAPPU	E3 ubiquitin-protein ligase. (805 aa)
	E9GL73_DAPPU	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (905 aa)
	E9GL76_DAPPU	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (600 aa)
	E9GLG3_DAPPU	CKK domain-containing protein. (144 aa)
	E9GLR9_DAPPU	WD_REPEATS_REGION domain-containing protein. (439 aa)
	E9GLX0_DAPPU	Protein kinase domain-containing protein. (611 aa)
	E9GNU2_DAPPU	F-box domain-containing protein. (532 aa)
	E9GNU9_DAPPU	F-box domain-containing protein. (411 aa)
	E9GP07_DAPPU	F-box domain-containing protein. (181 aa)
	E9GRE1_DAPPU	Uncharacterized protein. (512 aa)
	E9GRE2_DAPPU	Uncharacterized protein. (300 aa)
	E9GRE3_DAPPU	Uncharacterized protein. (4511 aa)
	E9GXU4_DAPPU	N-acetyltransferase domain-containing protein. (200 aa)
	E9H0Z1_DAPPU	F-box and WD40-domain protein. (262 aa)
	E9H233_DAPPU	Uncharacterized protein. (210 aa)
	E9H2U1_DAPPU	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (344 aa)
	E9H5U5_DAPPU	Spaetzle domain-containing protein. (225 aa)
	E9H8J8_DAPPU	Uncharacterized protein. (181 aa)
	E9HA21_DAPPU	Uncharacterized protein; Belongs to the peptidase C19 family. (1108 aa)
	E9HBK8_DAPPU	Uncharacterized protein. (470 aa)

Your Current Organism:

Daphnia pulex

NCBI taxonomy Id: 6669
Other names: D. pulex, common water flea

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DAPPUDRAFT_915	EOG090X060Z	E9GB21	E9HGD8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	EOG090X060Z.	0.967
E9FRE5_DAPPU	E9FSB4_DAPPU	E9FRE5	E9FSB4	TOG domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.493
E9FRE5_DAPPU	E9G2F4_DAPPU	E9FRE5	E9G2F4	TOG domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.843
E9FRE5_DAPPU	E9G2M5_DAPPU	E9FRE5	E9G2M5	TOG domain-containing protein.	Non-specific serine/threonine protein kinase.	0.739
E9FRE5_DAPPU	E9G331_DAPPU	E9FRE5	E9G331	TOG domain-containing protein.	Non-specific serine/threonine protein kinase.	0.594
E9FRE5_DAPPU	E9GEM8_DAPPU	E9FRE5	E9GEM8	TOG domain-containing protein.	Uncharacterized protein.	0.947
E9FRE5_DAPPU	E9H8J8_DAPPU	E9FRE5	E9H8J8	TOG domain-containing protein.	Uncharacterized protein.	0.756
E9FRE5_DAPPU	E9HI82_DAPPU	E9FRE5	E9HI82	TOG domain-containing protein.	Uncharacterized protein.	0.493
E9FRE5_DAPPU	E9I0W3_DAPPU	E9FRE5	E9I0W3	TOG domain-containing protein.	Serine/threonine-protein phosphatase.	0.999
E9FRE5_DAPPU	EOG090X0BA8	E9FRE5	E9FRG1	TOG domain-containing protein.	EOG090X0BA8.	0.894
E9FSB4_DAPPU	E9FRE5_DAPPU	E9FSB4	E9FRE5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	TOG domain-containing protein.	0.493
E9FSB4_DAPPU	E9GL76_DAPPU	E9FSB4	E9GL76	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.438
E9FSB4_DAPPU	E9I0W3_DAPPU	E9FSB4	E9I0W3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Serine/threonine-protein phosphatase.	0.523
E9FT39_DAPPU	E9GL76_DAPPU	E9FT39	E9GL76	Uncharacterized protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.509
E9FTF6_DAPPU	E9GP07_DAPPU	E9FTF6	E9GP07	F-box domain-containing protein.	F-box domain-containing protein.	0.414
E9FU96_DAPPU	E9G588_DAPPU	E9FU96	E9G588	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Uncharacterized protein.	0.830
E9FVU3_DAPPU	E9FVU5_DAPPU	E9FVU3	E9FVU5	Uncharacterized protein.	Protein kinase domain-containing protein.	0.900
E9FVU3_DAPPU	E9H2U1_DAPPU	E9FVU3	E9H2U1	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.484
E9FVU5_DAPPU	E9FVU3_DAPPU	E9FVU5	E9FVU3	Protein kinase domain-containing protein.	Uncharacterized protein.	0.900
E9FVU5_DAPPU	E9H2U1_DAPPU	E9FVU5	E9H2U1	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.529