47 items (Daphnia pulex) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	E9I0J4_DAPPU	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (101 aa)
	E9HN60_DAPPU	Uncharacterized protein; Belongs to the AAA ATPase family. (464 aa)
	TOR	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2517 aa)
	E9HFD3_DAPPU	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1048 aa)
	E9HB03_DAPPU	Uncharacterized protein. (431 aa)
	E9HAX7_DAPPU	Uncharacterized protein. (450 aa)
	E9HAD5_DAPPU	Sec8_exocyst domain-containing protein. (929 aa)
	EOG090X0AQE	EOG090X0AQE. (289 aa)
	E9H109_DAPPU	Uncharacterized protein. (694 aa)
	GBB	Putative TGF-beta ligand glass bottom boat protein. (459 aa)
	E9GZ92_DAPPU	Uncharacterized protein. (583 aa)
	E9GXQ9_DAPPU	Uncharacterized protein; Belongs to the MAGUK family. (814 aa)
	E9GX18_DAPPU	AAA domain-containing protein; Belongs to the AAA ATPase family. (617 aa)
	E9GV70_DAPPU	PKD_channel domain-containing protein. (673 aa)
	E9GUA8_DAPPU	Tudor domain-containing protein. (252 aa)
	E9GRP0_DAPPU	DRBM domain-containing protein. (131 aa)
	Rheb	Uncharacterized protein Rheb. (185 aa)
	E9GNK1_DAPPU	PDZ domain-containing protein. (85 aa)
	E9GLV6_DAPPU	Protein kinase domain-containing protein. (424 aa)
	E9GLV5_DAPPU	Protein kinase domain-containing protein. (277 aa)
	EOG090X098Y	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (275 aa)
	E9GJB7_DAPPU	Mothers against decapentaplegic homolog. (524 aa)
	E9GI95_DAPPU	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (381 aa)
	DAPPUDRAFT_915	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (498 aa)
	E9G926_DAPPU	Mitogen-activated protein kinase. (364 aa)
	E9G6W8_DAPPU	Uncharacterized protein. (1722 aa)
	E9G618_DAPPU	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (393 aa)
	E9G4A1_DAPPU	ANK_REP_REGION domain-containing protein. (287 aa)
	E9G2K6_DAPPU	Uncharacterized protein. (535 aa)
	E9FW97_DAPPU	Uncharacterized protein; Belongs to the actin family. (420 aa)
	E9FTP4_DAPPU	Uncharacterized protein. (1850 aa)
	E9FTP1_DAPPU	Death domain-containing protein. (754 aa)
	E9FTP0_DAPPU	ZU5 domain-containing protein. (218 aa)
	E9FT89_DAPPU	Uncharacterized protein. (479 aa)
	E9I0J2_DAPPU	C2 PI3K-type domain-containing protein; Belongs to the PI3/PI4-kinase family. (150 aa)
	E9I0J3_DAPPU	PIK helical domain-containing protein; Belongs to the PI3/PI4-kinase family. (191 aa)
	E9HQN2_DAPPU	ANK_REP_REGION domain-containing protein. (469 aa)
	E9I207_DAPPU	CRIB domain-containing protein. (94 aa)
	E9I3H5_DAPPU	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (238 aa)
	E9I7G7_DAPPU	Protein kinase domain-containing protein. (226 aa)
	E9I0J1_DAPPU	PI3K-ABD domain-containing protein; Belongs to the PI3/PI4-kinase family. (77 aa)
	E9HWV5_DAPPU	ANK_REP_REGION domain-containing protein. (110 aa)
	E9HVM8_DAPPU	FAT domain-containing protein. (56 aa)
	E9HU25_DAPPU	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1025 aa)
	E9HU18_DAPPU	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (934 aa)
	E9HTS0_DAPPU	Uncharacterized protein. (486 aa)
	SAX	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (576 aa)

Your Current Organism:

Daphnia pulex

NCBI taxonomy Id: 6669
Other names: D. pulex, common water flea

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E9FTP0_DAPPU	E9FTP1_DAPPU	E9FTP0	E9FTP1	ZU5 domain-containing protein.	Death domain-containing protein.	0.944
E9FTP1_DAPPU	E9FTP0_DAPPU	E9FTP1	E9FTP0	Death domain-containing protein.	ZU5 domain-containing protein.	0.944
E9FW97_DAPPU	E9G2K6_DAPPU	E9FW97	E9G2K6	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.624
E9FW97_DAPPU	E9G618_DAPPU	E9FW97	E9G618	Uncharacterized protein; Belongs to the actin family.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.999
E9FW97_DAPPU	EOG090X098Y	E9FW97	E9GL77	Uncharacterized protein; Belongs to the actin family.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.862
E9G2K6_DAPPU	E9FW97_DAPPU	E9G2K6	E9FW97	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.624
E9G2K6_DAPPU	E9G618_DAPPU	E9G2K6	E9G618	Uncharacterized protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.805
E9G2K6_DAPPU	EOG090X098Y	E9G2K6	E9GL77	Uncharacterized protein.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.842
E9G4A1_DAPPU	E9HWV5_DAPPU	E9G4A1	E9HWV5	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.458
E9G618_DAPPU	E9FW97_DAPPU	E9G618	E9FW97	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Uncharacterized protein; Belongs to the actin family.	0.999
E9G618_DAPPU	E9G2K6_DAPPU	E9G618	E9G2K6	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Uncharacterized protein.	0.805
E9G618_DAPPU	E9HTS0_DAPPU	E9G618	E9HTS0	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Uncharacterized protein.	0.414
E9G618_DAPPU	EOG090X098Y	E9G618	E9GL77	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.735
E9G6W8_DAPPU	E9I207_DAPPU	E9G6W8	E9I207	Uncharacterized protein.	CRIB domain-containing protein.	0.563
E9G6W8_DAPPU	E9I7G7_DAPPU	E9G6W8	E9I7G7	Uncharacterized protein.	Protein kinase domain-containing protein.	0.563
E9G6W8_DAPPU	Rheb	E9G6W8	E9GRL7	Uncharacterized protein.	Uncharacterized protein Rheb.	0.647
E9GI95_DAPPU	GBB	E9GI95	E9H0X5	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	Putative TGF-beta ligand glass bottom boat protein.	0.459
E9GJB7_DAPPU	GBB	E9GJB7	E9H0X5	Mothers against decapentaplegic homolog.	Putative TGF-beta ligand glass bottom boat protein.	0.591
E9GJB7_DAPPU	SAX	E9GJB7	E9HSW3	Mothers against decapentaplegic homolog.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.755
E9GRP0_DAPPU	E9H109_DAPPU	E9GRP0	E9H109	DRBM domain-containing protein.	Uncharacterized protein.	0.547