(49 nodes) Regulation of dendrite development network (Daphnia pulex)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	E9I0J3_DAPPU	PIK helical domain-containing protein; Belongs to the PI3/PI4-kinase family. (191 aa)
	E9FTB3_DAPPU	Uncharacterized protein. (1114 aa)
	E9FTW1_DAPPU	TGF_BETA_2 domain-containing protein. (119 aa)
	E9FUI3_DAPPU	Uncharacterized protein. (1406 aa)
	E9FV61_DAPPU	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (769 aa)
	E9FVX6_DAPPU	HECT domain-containing protein. (431 aa)
	E9FWG8_DAPPU	Uncharacterized protein. (426 aa)
	E9FYQ9_DAPPU	Uncharacterized protein. (581 aa)
	E9FYR0_DAPPU	Uncharacterized protein. (1142 aa)
	E9FZD2_DAPPU	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (521 aa)
	E9FZJ5_DAPPU	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (199 aa)
	E9G2B3_DAPPU	IPT/TIG domain-containing protein. (363 aa)
	E9G2K6_DAPPU	Uncharacterized protein. (535 aa)
	E9G2M5_DAPPU	Non-specific serine/threonine protein kinase. (532 aa)
	E9G3Q7_DAPPU	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (192 aa)
	E9G8Z2_DAPPU	Uncharacterized protein. (386 aa)
	E9GAT8_DAPPU	Uncharacterized protein. (355 aa)
	E9GFW2_DAPPU	Phosphatase and tensin-like protein. (280 aa)
	E9GGD9_DAPPU	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (192 aa)
	E9GKW9_DAPPU	Uncharacterized protein. (773 aa)
	E9GPV8_DAPPU	Uncharacterized protein. (779 aa)
	E9GPW1_DAPPU	COR domain-containing protein. (528 aa)
	E9GPX3_DAPPU	Uncharacterized protein. (1563 aa)
	E9GPZ4_DAPPU	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (453 aa)
	E9GT09_DAPPU	Uncharacterized protein. (115 aa)
	E9GT44_DAPPU	Uncharacterized protein. (275 aa)
	E9GU22_DAPPU	Caprin-1_dimer domain-containing protein. (619 aa)
	E9GVF5_DAPPU	NUDE_C domain-containing protein. (307 aa)
	E9GX18_DAPPU	AAA domain-containing protein; Belongs to the AAA ATPase family. (617 aa)
	E9GZ90_DAPPU	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (78 aa)
	E9GZC4_DAPPU	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (590 aa)
	EOG090X07YX	EOG090X07YX. (359 aa)
	E9H4B8_DAPPU	Uncharacterized protein. (514 aa)
	E9H4M9_DAPPU	CS domain-containing protein. (331 aa)
	E9H5J3_DAPPU	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa)
	E9HDV7_DAPPU	Uncharacterized protein. (1861 aa)
	E9HDV8_DAPPU	Protein kinase domain-containing protein. (597 aa)
	E9HFD3_DAPPU	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1048 aa)
	E9HM46_DAPPU	Uncharacterized protein. (178 aa)
	E9HN60_DAPPU	Uncharacterized protein; Belongs to the AAA ATPase family. (464 aa)
	E9HU18_DAPPU	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (934 aa)
	E9HU25_DAPPU	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1025 aa)
	E9I0J1_DAPPU	PI3K-ABD domain-containing protein; Belongs to the PI3/PI4-kinase family. (77 aa)
	E9I0J2_DAPPU	C2 PI3K-type domain-containing protein; Belongs to the PI3/PI4-kinase family. (150 aa)
	E9I0J4_DAPPU	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (101 aa)
	E9I3H5_DAPPU	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (238 aa)
	E9I3X8_DAPPU	Protein kinase domain-containing protein. (162 aa)
	E9I408_DAPPU	Protein kinase domain-containing protein. (85 aa)
	E9I6L7_DAPPU	NUDE_C domain-containing protein. (156 aa)

Your Current Organism:

Daphnia pulex

NCBI taxonomy Id: 6669
Other names: D. pulex, common water flea

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E9FV61_DAPPU	E9FZJ5_DAPPU	E9FV61	E9FZJ5	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family.	0.949
E9FV61_DAPPU	E9G3Q7_DAPPU	E9FV61	E9G3Q7	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family.	0.949
E9FV61_DAPPU	E9GGD9_DAPPU	E9FV61	E9GGD9	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family.	0.949
E9FV61_DAPPU	E9GT09_DAPPU	E9FV61	E9GT09	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein.	0.949
E9FV61_DAPPU	E9GT44_DAPPU	E9FV61	E9GT44	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein.	0.949
E9FVX6_DAPPU	E9GFW2_DAPPU	E9FVX6	E9GFW2	HECT domain-containing protein.	Phosphatase and tensin-like protein.	0.500
E9FVX6_DAPPU	E9GPV8_DAPPU	E9FVX6	E9GPV8	HECT domain-containing protein.	Uncharacterized protein.	0.433
E9FVX6_DAPPU	E9GPW1_DAPPU	E9FVX6	E9GPW1	HECT domain-containing protein.	COR domain-containing protein.	0.433
E9FVX6_DAPPU	E9GPX3_DAPPU	E9FVX6	E9GPX3	HECT domain-containing protein.	Uncharacterized protein.	0.433
E9FVX6_DAPPU	E9GPZ4_DAPPU	E9FVX6	E9GPZ4	HECT domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.769
E9FVX6_DAPPU	E9HDV7_DAPPU	E9FVX6	E9HDV7	HECT domain-containing protein.	Uncharacterized protein.	0.433
E9FVX6_DAPPU	E9HDV8_DAPPU	E9FVX6	E9HDV8	HECT domain-containing protein.	Protein kinase domain-containing protein.	0.433
E9FVX6_DAPPU	E9HM46_DAPPU	E9FVX6	E9HM46	HECT domain-containing protein.	Uncharacterized protein.	0.575
E9FZD2_DAPPU	E9GVF5_DAPPU	E9FZD2	E9GVF5	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	NUDE_C domain-containing protein.	0.429
E9FZD2_DAPPU	E9H4M9_DAPPU	E9FZD2	E9H4M9	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	CS domain-containing protein.	0.752
E9FZD2_DAPPU	E9I6L7_DAPPU	E9FZD2	E9I6L7	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	NUDE_C domain-containing protein.	0.429
E9FZJ5_DAPPU	E9FV61_DAPPU	E9FZJ5	E9FV61	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.949
E9FZJ5_DAPPU	E9G3Q7_DAPPU	E9FZJ5	E9G3Q7	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family.	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family.	0.554
E9FZJ5_DAPPU	E9GGD9_DAPPU	E9FZJ5	E9GGD9	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family.	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family.	0.554
E9FZJ5_DAPPU	E9GT09_DAPPU	E9FZJ5	E9GT09	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family.	Uncharacterized protein.	0.569