(7 nodes) TSC1-TSC2 complex network (Daphnia pulex)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	E9G2M5_DAPPU	Non-specific serine/threonine protein kinase. (532 aa)
	E9G367_DAPPU	S6 kinase-like protein; Belongs to the protein kinase superfamily. (386 aa)
	E9GLF0_DAPPU	Rab-GAP TBC domain-containing protein. (299 aa)
	Rheb	Uncharacterized protein Rheb. (185 aa)
	TSC2	Putative tuberous sclerosis 2 isoform 3-like protein. (1640 aa)
	E9HF04_DAPPU	Uncharacterized protein. (175 aa)
	TSC-1	Tuber sclerosis 1-like protein. (262 aa)

Your Current Organism:

Daphnia pulex

NCBI taxonomy Id: 6669
Other names: D. pulex, common water flea

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E9G2M5_DAPPU	E9G367_DAPPU	E9G2M5	E9G367	Non-specific serine/threonine protein kinase.	S6 kinase-like protein; Belongs to the protein kinase superfamily.	0.874
E9G2M5_DAPPU	E9GLF0_DAPPU	E9G2M5	E9GLF0	Non-specific serine/threonine protein kinase.	Rab-GAP TBC domain-containing protein.	0.947
E9G2M5_DAPPU	E9HF04_DAPPU	E9G2M5	E9HF04	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.795
E9G2M5_DAPPU	Rheb	E9G2M5	E9GRL7	Non-specific serine/threonine protein kinase.	Uncharacterized protein Rheb.	0.847
E9G2M5_DAPPU	TSC-1	E9G2M5	E9FWB2	Non-specific serine/threonine protein kinase.	Tuber sclerosis 1-like protein.	0.795
E9G2M5_DAPPU	TSC2	E9G2M5	E9HI87	Non-specific serine/threonine protein kinase.	Putative tuberous sclerosis 2 isoform 3-like protein.	0.988
E9G367_DAPPU	E9G2M5_DAPPU	E9G367	E9G2M5	S6 kinase-like protein; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.874
E9G367_DAPPU	E9HF04_DAPPU	E9G367	E9HF04	S6 kinase-like protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.548
E9G367_DAPPU	Rheb	E9G367	E9GRL7	S6 kinase-like protein; Belongs to the protein kinase superfamily.	Uncharacterized protein Rheb.	0.896
E9G367_DAPPU	TSC-1	E9G367	E9FWB2	S6 kinase-like protein; Belongs to the protein kinase superfamily.	Tuber sclerosis 1-like protein.	0.548
E9G367_DAPPU	TSC2	E9G367	E9HI87	S6 kinase-like protein; Belongs to the protein kinase superfamily.	Putative tuberous sclerosis 2 isoform 3-like protein.	0.902
E9GLF0_DAPPU	E9G2M5_DAPPU	E9GLF0	E9G2M5	Rab-GAP TBC domain-containing protein.	Non-specific serine/threonine protein kinase.	0.947
E9GLF0_DAPPU	E9HF04_DAPPU	E9GLF0	E9HF04	Rab-GAP TBC domain-containing protein.	Uncharacterized protein.	0.972
E9GLF0_DAPPU	Rheb	E9GLF0	E9GRL7	Rab-GAP TBC domain-containing protein.	Uncharacterized protein Rheb.	0.965
E9GLF0_DAPPU	TSC-1	E9GLF0	E9FWB2	Rab-GAP TBC domain-containing protein.	Tuber sclerosis 1-like protein.	0.972
E9GLF0_DAPPU	TSC2	E9GLF0	E9HI87	Rab-GAP TBC domain-containing protein.	Putative tuberous sclerosis 2 isoform 3-like protein.	0.999
E9HF04_DAPPU	E9G2M5_DAPPU	E9HF04	E9G2M5	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.795
E9HF04_DAPPU	E9G367_DAPPU	E9HF04	E9G367	Uncharacterized protein.	S6 kinase-like protein; Belongs to the protein kinase superfamily.	0.548
E9HF04_DAPPU	E9GLF0_DAPPU	E9HF04	E9GLF0	Uncharacterized protein.	Rab-GAP TBC domain-containing protein.	0.972
E9HF04_DAPPU	Rheb	E9HF04	E9GRL7	Uncharacterized protein.	Uncharacterized protein Rheb.	0.970