(21 nodes) Recycling pathway of L1 network (Daphnia pulex)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	E9HXR5_DAPPU	B2-adapt-app_C domain-containing protein. (128 aa)
	ACT2A	Muscle-specific actin. (376 aa)
	E9FWB9_DAPPU	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (885 aa)
	ACT1A	Cytoplasmatic actin. (376 aa)
	E9FYM6_DAPPU	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (434 aa)
	E9GIN4_DAPPU	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	E9GKM8_DAPPU	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (943 aa)
	E9GM88_DAPPU	Uncharacterized protein. (331 aa)
	E9I210_DAPPU	Adaptin_N domain-containing protein. (636 aa)
	E9GTP3_DAPPU	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1663 aa)
	E9H0L3_DAPPU	AP complex subunit beta. (930 aa)
	ACT1D	Cytoplasmatic actin; Belongs to the actin family. (374 aa)
	E9H5J7_DAPPU	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (265 aa)
	E9H6S4_DAPPU	Uncharacterized protein. (465 aa)
	E9H9F6_DAPPU	FERM domain-containing protein. (573 aa)
	E9HF28_DAPPU	Uncharacterized protein. (470 aa)
	ACT1B	Cytoplasmatic actin. (376 aa)
	E9HH54_DAPPU	Uncharacterized protein. (566 aa)
	E9HH55_DAPPU	Uncharacterized protein. (826 aa)
	E9HMP3_DAPPU	Uncharacterized protein. (392 aa)
	E9HVQ6_DAPPU	Uncharacterized protein. (627 aa)

Your Current Organism:

Daphnia pulex

NCBI taxonomy Id: 6669
Other names: D. pulex, common water flea

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E9FWB9_DAPPU	E9FYM6_DAPPU	E9FWB9	E9FYM6	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.737
E9FWB9_DAPPU	E9GIN4_DAPPU	E9FWB9	E9GIN4	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.663
E9FWB9_DAPPU	E9GKM8_DAPPU	E9FWB9	E9GKM8	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.798
E9FWB9_DAPPU	E9GTP3_DAPPU	E9FWB9	E9GTP3	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.797
E9FWB9_DAPPU	E9H0L3_DAPPU	E9FWB9	E9H0L3	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	AP complex subunit beta.	0.623
E9FWB9_DAPPU	E9H5J7_DAPPU	E9FWB9	E9H5J7	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.772
E9FWB9_DAPPU	E9HMP3_DAPPU	E9FWB9	E9HMP3	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.927
E9FWB9_DAPPU	E9HVQ6_DAPPU	E9FWB9	E9HVQ6	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.797
E9FWB9_DAPPU	E9HXR5_DAPPU	E9FWB9	E9HXR5	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	B2-adapt-app_C domain-containing protein.	0.623
E9FWB9_DAPPU	E9I210_DAPPU	E9FWB9	E9I210	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Adaptin_N domain-containing protein.	0.623
E9FYM6_DAPPU	E9FWB9_DAPPU	E9FYM6	E9FWB9	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.737
E9FYM6_DAPPU	E9GIN4_DAPPU	E9FYM6	E9GIN4	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.999
E9FYM6_DAPPU	E9GKM8_DAPPU	E9FYM6	E9GKM8	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.999
E9FYM6_DAPPU	E9GTP3_DAPPU	E9FYM6	E9GTP3	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.921
E9FYM6_DAPPU	E9H0L3_DAPPU	E9FYM6	E9H0L3	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP complex subunit beta.	0.966
E9FYM6_DAPPU	E9H5J7_DAPPU	E9FYM6	E9H5J7	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.938
E9FYM6_DAPPU	E9HMP3_DAPPU	E9FYM6	E9HMP3	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	Uncharacterized protein.	0.736
E9FYM6_DAPPU	E9HVQ6_DAPPU	E9FYM6	E9HVQ6	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	Uncharacterized protein.	0.921
E9FYM6_DAPPU	E9HXR5_DAPPU	E9FYM6	E9HXR5	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	B2-adapt-app_C domain-containing protein.	0.966
E9FYM6_DAPPU	E9I210_DAPPU	E9FYM6	E9I210	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	Adaptin_N domain-containing protein.	0.949