(31 nodes) Mitophagy - animal network (Daphnia pulex)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	E9FRG0_DAPPU	Protein kinase domain-containing protein. (742 aa)
	E9FUS6_DAPPU	Uncharacterized protein. (189 aa)
	E9FV00_DAPPU	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (584 aa)
	E9FZ09_DAPPU	Uncharacterized protein. (198 aa)
	E9G008_DAPPU	Uncharacterized protein. (203 aa)
	E9G0L1_DAPPU	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (481 aa)
	E9G0U3_DAPPU	USP domain-containing protein; Belongs to the peptidase C19 family. (383 aa)
	E9G1Y1_DAPPU	BZIP domain-containing protein. (366 aa)
	E9G615_DAPPU	Putative hypoxia inducible factor-1 alpha. (846 aa)
	E9GA50_DAPPU	Mitogen-activated protein kinase. (380 aa)
	E9GA52_DAPPU	Mitogen-activated protein kinase. (378 aa)
	E9GCV0_DAPPU	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (352 aa)
	E9GDE1_DAPPU	Rab-GAP TBC domain-containing protein. (577 aa)
	EOG090X01A3	EOG090X01A3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (760 aa)
	E9GJF3_DAPPU	Uncharacterized protein. (764 aa)
	E9GM54_DAPPU	Ubiquitin-like domain-containing protein. (111 aa)
	EOG090X048D	EOG090X048D. (440 aa)
	E9GTE8_DAPPU	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (221 aa)
	E9GTZ0_DAPPU	BZIP domain-containing protein. (296 aa)
	E9GUW1_DAPPU	Uncharacterized protein. (208 aa)
	E9GY59_DAPPU	Uncharacterized protein. (732 aa)
	E9GZ23_DAPPU	Uncharacterized protein. (602 aa)
	FOXO	Forkhead box-like protein, sub-group 0. (608 aa)
	E9H688_DAPPU	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (627 aa)
	EOG090X0BB3	Autophagy protein 5; Involved in autophagic vesicle formation. (271 aa)
	E9HA45_DAPPU	Ubiquitin carboxyl-terminal hydrolase. (869 aa)
	E9HBT7_DAPPU	Uncharacterized protein. (227 aa)
	E9HCY2_DAPPU	Uncharacterized protein. (150 aa)
	E9HNB5_DAPPU	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (149 aa)
	E9HVD0_DAPPU	Uncharacterized protein. (323 aa)
	E9I1I7_DAPPU	Uncharacterized protein. (190 aa)

Your Current Organism:

Daphnia pulex

NCBI taxonomy Id: 6669
Other names: D. pulex, common water flea

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E9FRG0_DAPPU	E9GJF3_DAPPU	E9FRG0	E9GJF3	Protein kinase domain-containing protein.	Uncharacterized protein.	0.673
E9FRG0_DAPPU	E9GM54_DAPPU	E9FRG0	E9GM54	Protein kinase domain-containing protein.	Ubiquitin-like domain-containing protein.	0.576
E9FRG0_DAPPU	E9GZ23_DAPPU	E9FRG0	E9GZ23	Protein kinase domain-containing protein.	Uncharacterized protein.	0.957
E9FUS6_DAPPU	E9FZ09_DAPPU	E9FUS6	E9FZ09	Uncharacterized protein.	Uncharacterized protein.	0.959
E9FUS6_DAPPU	E9G008_DAPPU	E9FUS6	E9G008	Uncharacterized protein.	Uncharacterized protein.	0.472
E9FUS6_DAPPU	E9GA50_DAPPU	E9FUS6	E9GA50	Uncharacterized protein.	Mitogen-activated protein kinase.	0.919
E9FUS6_DAPPU	E9GA52_DAPPU	E9FUS6	E9GA52	Uncharacterized protein.	Mitogen-activated protein kinase.	0.919
E9FUS6_DAPPU	E9HBT7_DAPPU	E9FUS6	E9HBT7	Uncharacterized protein.	Uncharacterized protein.	0.949
E9FUS6_DAPPU	E9I1I7_DAPPU	E9FUS6	E9I1I7	Uncharacterized protein.	Uncharacterized protein.	0.621
E9FUS6_DAPPU	EOG090X01A3	E9FUS6	E9GGH3	Uncharacterized protein.	EOG090X01A3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.733
E9FUS6_DAPPU	EOG090X048D	E9FUS6	E9GRR3	Uncharacterized protein.	EOG090X048D.	0.996
E9FUS6_DAPPU	EOG090X0BB3	E9FUS6	E9H8N6	Uncharacterized protein.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.591
E9FV00_DAPPU	E9GZ23_DAPPU	E9FV00	E9GZ23	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	Uncharacterized protein.	0.425
E9FV00_DAPPU	E9HNB5_DAPPU	E9FV00	E9HNB5	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.	0.420
E9FV00_DAPPU	EOG090X048D	E9FV00	E9GRR3	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	EOG090X048D.	0.905
E9FV00_DAPPU	EOG090X0BB3	E9FV00	E9H8N6	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.730
E9FZ09_DAPPU	E9FUS6_DAPPU	E9FZ09	E9FUS6	Uncharacterized protein.	Uncharacterized protein.	0.959
E9FZ09_DAPPU	E9G0L1_DAPPU	E9FZ09	E9G0L1	Uncharacterized protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.	0.579
E9FZ09_DAPPU	E9G615_DAPPU	E9FZ09	E9G615	Uncharacterized protein.	Putative hypoxia inducible factor-1 alpha.	0.412
E9FZ09_DAPPU	E9HCY2_DAPPU	E9FZ09	E9HCY2	Uncharacterized protein.	Uncharacterized protein.	0.697