STRINGSTRING
ABC0858 ABC0858 ABC0794 ABC0794 ABC3195 ABC3195 ABC3188 ABC3188 ABC3176 ABC3176 pgk pgk tpi tpi pgm pgm eno eno ABC2973 ABC2973 pgi pgi ldh ldh pfk pfk pykA pykA citZ citZ citC citC mdh mdh etfB etfB etfA etfA sdhC sdhC sdhB sdhB ABC2655 ABC2655 ABC2531 ABC2531 bkdB bkdB pdhA pdhA pdhB pdhB pdhC pdhC ctaC ctaC ctaD ctaD ctaE ctaE mrpD mrpD ABC0768 ABC0768 narI narI narH narH narG narG ABC0547 ABC0547 ABC0534 ABC0534 ABC0445 ABC0445 ABC0429 ABC0429 iolJ iolJ ctaF ctaF ABC0324 ABC0324 cccB cccB ABC2389 ABC2389 pyrDII pyrDII rpe rpe sucC sucC sucD sucD glcB glcB tkt tkt citB citB qoxA qoxA qoxB qoxB qoxC qoxC qoxD qoxD odhA odhA odhB odhB ABC1926 ABC1926 zwf zwf qcrC qcrC qcrB qcrB qcrA qcrA ABC1857 ABC1857 fer fer mmgD mmgD citG citG ansB ansB glcK glcK ABC1691 ABC1691 ABC1632 ABC1632 ABC1552 ABC1552 ABC1287 ABC1287 rpiA rpiA ABC3444 ABC3444 ABC3502 ABC3502 ABC3505 ABC3505 ABC3568 ABC3568 ABC3634 ABC3634 azoR azoR tal tal fbaA fbaA ABC3946 ABC3946 scoE scoE scoA scoA ABC4035 ABC4035 citA citA ABC1106 ABC1106 ABC1100 ABC1100 ABC0948 ABC0948
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABC0858Fructose-bisphosphate aldolase. (289 aa)
ABC0794Conserved hypothetical protein. (283 aa)
ABC3195Fructose-bisphosphate aldolase. (289 aa)
ABC3188Conserved hypothetical protein. (184 aa)
ABC3176Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (79 aa)
pgk3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (394 aa)
tpiTriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
pgm2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. (510 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
ABC2973Isocitrate lyase. (423 aa)
pgiGlucose-6-phosphate isomerase A. (451 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (325 aa)
pfk6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)
pykAPyruvate kinase; Belongs to the pyruvate kinase family. (584 aa)
citZCitrate synthase II; Belongs to the citrate synthase family. (371 aa)
citCIsocitrate dehydrogenase [NADP]. (421 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (314 aa)
etfBElectron transfer flavoprotein beta subunit. (256 aa)
etfAElectron transfer flavoprotein alpha subunit. (325 aa)
sdhCSuccinate dehydrogenase cytochrome b558 subunit. (202 aa)
sdhBSuccinate dehydrogenase iron-sulfur protein. (250 aa)
ABC2655Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (79 aa)
ABC2531Conserved hypothetical protein. (75 aa)
bkdBBranched-chain alpha-keto acid dehydrogenase E2 component. (418 aa)
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (361 aa)
pdhBPyruvate dehydrogenase E1 component beta subunit. (325 aa)
pdhCPyruvate dehydrogenase E2 component. (425 aa)
ctaCCytochrome caa3 oxidase subunit II CoxB; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). (345 aa)
ctaDCytochrome caa3 oxidase subunit I CoxA; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (624 aa)
ctaECytochrome caa3 oxidase subunit III CoxC. (207 aa)
mrpDMultiple resistance and pH regulation related protein MrpD. (495 aa)
ABC07683-carboxymuconate cyclase. (354 aa)
narIRespiratory nitrate reductase gamma chain. (228 aa)
narHRespiratory nitrate reductase beta chain. (511 aa)
narGRespiratory nitrate reductase alpha chain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1224 aa)
ABC0547hydroxymethylglutaryl-CoA lyase. (309 aa)
ABC0534Multimeric flavodoxin WrbA; Belongs to the WrbA family. (204 aa)
ABC0445Fructose-bisphosphate aldolase. (291 aa)
ABC0429Myo-inositol 2-dehydrogenase. (340 aa)
iolJFructose-bisphosphate aldolase; Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6- phospho-5-dehydro-2-deoxy-D-gluconate (DKGP); Belongs to the class II fructose-bisphosphate aldolase family. IolJ subfamily. (293 aa)
ctaFCytochrome caa3 oxidase subunit IV CoxD. (115 aa)
ABC0324Ferredoxin. (105 aa)
cccBCytochrome c551. (108 aa)
ABC2389Conserved hypothetical protein. (183 aa)
pyrDIIDihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (259 aa)
rpeRibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (215 aa)
sucCsuccinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa)
sucDsuccinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (304 aa)
glcBMalate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (727 aa)
tktTransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (665 aa)
citBAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (905 aa)
qoxACytochrome aa3 quinol oxidase subunit II QoxA; Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I. (326 aa)
qoxBCytochrome aa3 quinol oxidase subunit I QoxB; Belongs to the heme-copper respiratory oxidase family. (647 aa)
qoxCCytochrome aa3 quinol oxidase subunit III QoxC. (204 aa)
qoxDCytochrome aa3 quinol oxidase subunit IV QoxD. (104 aa)
odhA2-oxoglutarate dehydrogenase E1 component; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). (943 aa)
odhB2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (420 aa)
ABC1926Decarboxylating 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (469 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (495 aa)
qcrCMenaquinol-cytochrome c reductase cytochrome b/c subunit; Component of the menaquinol-cytochrome c reductase complex. (258 aa)
qcrBMenaquinol-cytochrome c reductase cytochrome b subunit. (223 aa)
qcrAMenaquinol-cytochrome c reductase iron-sulfur subunit. (163 aa)
ABC1857MarR family transcriptional regulator. (302 aa)
ferFerredoxin. (83 aa)
mmgDCitrate synthase; Belongs to the citrate synthase family. (373 aa)
citGFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (462 aa)
ansBAspartate ammonia-lyase. (470 aa)
glcKGlucokinase. (326 aa)
ABC1691Cytochrome c551. (127 aa)
ABC1632Multiple resistance and pH regulation related protein MrpD. (493 aa)
ABC1552Hypothetical protein. (124 aa)
ABC1287Cytochrome d ubiquinol oxidase subunit I CydA. (445 aa)
rpiARibose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (228 aa)
ABC3444Conserved hypothetical protein. (410 aa)
ABC35026-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (334 aa)
ABC3505Fructose-bisphosphate aldolase. (284 aa)
ABC3568Fructose-bisphosphate aldolase. (289 aa)
ABC3634Conserved hypothetical protein. (388 aa)
azoRAcyl carrier protein phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. (207 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (216 aa)
fbaAFructose-bisphosphate aldolase. (287 aa)
ABC3946Rieske [2Fe-2S] iron-sulfur protein. (505 aa)
scoEsuccinyl-CoA:3-ketoacid-coenzyme A transferase subunit B. (213 aa)
scoAsuccinyl-CoA:3-ketoacid-coenzyme A transferase subunit A. (237 aa)
ABC4035Conserved hypothetical protein. (396 aa)
citACitrate synthase I; Belongs to the citrate synthase family. (363 aa)
ABC1106Transketolase; Belongs to the transketolase family. (668 aa)
ABC1100Flavodoxin. (152 aa)
ABC0948Transketolase; Belongs to the transketolase family. (666 aa)
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
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