STRINGSTRING
ftsI ftsI C8T0S9_KLEPR C8T0S9_KLEPR ybjG ybjG dacA dacA GCA_000827775_00137 GCA_000827775_00137 ybhC ybhC mrdA mrdA GCA_000827775_00359 GCA_000827775_00359 mrdB mrdB rlpA rlpA dacA-2 dacA-2 mltA mltA ycjI ycjI nagZ nagZ mltG mltG mviN mviN mtgA mtgA murA murA mltC mltC ddlA ddlA C8T4J1_KLEPR C8T4J1_KLEPR matC matC cpdA cpdA uppP uppP mrkB mrkB fimC fimC dacA3 dacA3 C8SYG6_KLEPR C8SYG6_KLEPR lytS lytS yehU yehU pbpG pbpG mltF mltF GCA_000827775_02285 GCA_000827775_02285 C8TDB9_KLEPR C8TDB9_KLEPR C8TD82_KLEPR C8TD82_KLEPR C8TD51_KLEPR C8TD51_KLEPR fimC2 fimC2 mpl mpl glmU glmU C8T9T9_KLEPR C8T9T9_KLEPR C8T9U3_KLEPR C8T9U3_KLEPR mrdA2 mrdA2 GCA_000827775_03544 GCA_000827775_03544 ydhO ydhO slt slt GCA_000827775_03835 GCA_000827775_03835 murE murE murF murF mraY mraY murD murD ftsW ftsW murG murG murC murC ddlB ddlB mrcB mrcB uppS uppS emtA emtA idcA idcA ftsI-2 ftsI-2 yebA yebA ypdA ypdA C8T7M1_KLEPR C8T7M1_KLEPR C8T836_KLEPR C8T836_KLEPR C8T8Q5_KLEPR C8T8Q5_KLEPR stgB stgB murI murI wecA wecA murB murB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ftsIUnannotated protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. (359 aa)
C8T0S9_KLEPRUnannotated protein. (259 aa)
ybjGUnannotated protein. (197 aa)
dacAUnannotated protein; Belongs to the peptidase S11 family. (239 aa)
GCA_000827775_00137Unannotated protein. (166 aa)
ybhCUnannotated protein. (427 aa)
mrdAUnannotated protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (464 aa)
GCA_000827775_00359Unannotated protein. (183 aa)
mrdBUnannotated protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (370 aa)
rlpAUnannotated protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (365 aa)
dacA-2Unannotated protein; Belongs to the peptidase S11 family. (423 aa)
mltAUnannotated protein; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (365 aa)
ycjIUnannotated protein. (235 aa)
nagZUnannotated protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (340 aa)
mltGUnannotated protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (340 aa)
mviNUnannotated protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (511 aa)
mtgAUnannotated protein; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (241 aa)
murAUnannotated protein; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (419 aa)
mltCUnannotated protein; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (361 aa)
ddlAUnannotated protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (365 aa)
C8T4J1_KLEPRUnannotated protein. (236 aa)
matCUnannotated protein. (222 aa)
cpdAUnannotated protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (275 aa)
uppPUnannotated protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (273 aa)
mrkBUnannotated protein. (233 aa)
fimCUnannotated protein. (234 aa)
dacA3Unannotated protein; Belongs to the peptidase S11 family. (387 aa)
C8SYG6_KLEPRUnannotated protein. (169 aa)
lytSUnannotated protein. (264 aa)
yehUUnannotated protein. (128 aa)
pbpGUnannotated protein; Belongs to the peptidase S11 family. (316 aa)
mltFUnannotated protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. (369 aa)
GCA_000827775_02285Unannotated protein. (117 aa)
C8TDB9_KLEPRUnannotated protein. (151 aa)
C8TD82_KLEPRUnannotated protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family. (526 aa)
C8TD51_KLEPRUnannotated protein. (229 aa)
fimC2Unannotated protein. (228 aa)
mplUnannotated protein; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (457 aa)
glmUUnannotated protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (456 aa)
C8T9T9_KLEPRUnannotated protein. (231 aa)
C8T9U3_KLEPRUnannotated protein. (430 aa)
mrdA2Unannotated protein. (280 aa)
GCA_000827775_03544Unannotated protein. (163 aa)
ydhOUnannotated protein. (127 aa)
sltUnannotated protein. (645 aa)
GCA_000827775_03835Unannotated protein. (167 aa)
murEUnannotated protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (495 aa)
murFUnannotated protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (452 aa)
mraYUnannotated protein; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa)
murDUnannotated protein; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (438 aa)
ftsWUnannotated protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (424 aa)
murGUnannotated protein; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (348 aa)
murCUnannotated protein; Cell wall formation; Belongs to the MurCDEF family. (491 aa)
ddlBUnannotated protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (306 aa)
mrcBUnannotated protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (850 aa)
uppSUnannotated protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (258 aa)
emtAUnannotated protein. (203 aa)
idcAUnannotated protein. (304 aa)
ftsI-2Unannotated protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (581 aa)
yebAUnannotated protein. (439 aa)
ypdAUnannotated protein. (565 aa)
C8T7M1_KLEPRUnannotated protein. (313 aa)
C8T836_KLEPRUnannotated protein. (904 aa)
C8T8Q5_KLEPRUnannotated protein. (256 aa)
stgBUnannotated protein. (220 aa)
murIUnannotated protein; Provides the (R)-glutamate required for cell wall biosynthesis. (283 aa)
wecAUnannotated protein; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). (367 aa)
murBUnannotated protein; Cell wall formation. (342 aa)
Your Current Organism:
Klebsiella pneumoniae rhinoscleromatis
NCBI taxonomy Id: 667127
Other names: K. pneumoniae subsp. rhinoscleromatis ATCC 13884, Klebsiella pneumoniae subsp. rhinoscleromatis ATCC 13884, Klebsiella pneumoniae subsp. rhinoscleromatis str. ATCC 13884, Klebsiella pneumoniae subsp. rhinoscleromatis strain ATCC 13884
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