(38 nodes) Apoptotic signaling pathway network (Penaeus vannamei)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Your Input:
	C7M84_024670	Putative serine/threonine-protein kinase. (1140 aa)
	C7M84_021403	Putative interferon alpha-inducible protein 6 isoform X1. (136 aa)
	C7M84_021872	Uncharacterized protein. (172 aa)
	C7M84_023076	Putative serine/threonine-protein kinase Chk2-like; Belongs to the protein kinase superfamily. (478 aa)
	C7M84_023257	Uncharacterized protein; Belongs to the peptidase C14A family. (545 aa)
	C7M84_024684	Putative cyclin-dependent kinase 5 activator 1-like. (209 aa)
	C7M84_025556	Uncharacterized protein. (382 aa)
	C7M84_000657	Uncharacterized protein. (1415 aa)
	C7M84_001153	Putative interferon alpha-inducible protein 27-like protein 2B-like isoform X1. (178 aa)
	C7M84_001363	Hippo. (647 aa)
	C7M84_003234	Mitogen-activated protein kinase kinase kinase 4. (263 aa)
	C7M84_004718	Putative DNA-dependent protein kinase catalytic subunit-like; Belongs to the PI3/PI4-kinase family. (449 aa)
	C7M84_006009	Putative DNA excision repair protein ERCC-6-like. (1432 aa)
	C7M84_006024	Ataxia telangiectasia mutated; Belongs to the PI3/PI4-kinase family. (2731 aa)
	C7M84_008467	Putative transcription factor Dp-1 isoform X2. (579 aa)
	C7M84_009818	Putative apoptosis regulatory protein Siva. (165 aa)
	C7M84_010769	Putative peptidyl-prolyl cis-trans isomerase, rhodopsin-specific isozyme. (746 aa)
	C7M84_015259	Inositol-requiring enzyme-1. (1151 aa)
	C7M84_017993	Influenza virus NS1A-binding protein-like protein A. (719 aa)
	C7M84_019264	Uncharacterized protein. (445 aa)
	C7M84_008259	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (234 aa)
	C7M84_011606	P53 protein. (462 aa)
	C7M84_012758	Putative BCL2/adenovirus E1B 19 kDa protein-interacting protein. (284 aa)
	C7M84_002021	Uncharacterized protein. (2304 aa)
	C7M84_016698	PRA1 family protein. (210 aa)
	C7M84_015567	Retinoblastoma family-like protein. (244 aa)
	C7M84_018698	Uncharacterized protein; Belongs to the peptidase C14A family. (664 aa)
	C7M84_003621	Bcl-2-related ovarian killer protein-like A. (258 aa)
	C7M84_015600	Mitochondrial Rho GTPase 1. (875 aa)
	C7M84_001868	Uncharacterized protein. (1258 aa)
	C7M84_010543	Death-associated protein-like. (102 aa)
	C7M84_023895	Uncharacterized protein; Belongs to the peptidase C14A family. (641 aa)
	C7M84_001170	P53 protein. (233 aa)
	C7M84_004719	Putative DNA-dependent protein kinase catalytic subunit-like. (2772 aa)
	C7M84_006208	Uncharacterized protein. (231 aa)
	C7M84_007382	Putative nibrin. (180 aa)
	C7M84_010767	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (264 aa)
	C7M84_012029	Apoptosis regulator BAX. (458 aa)

Your Current Organism:

Penaeus vannamei

NCBI taxonomy Id: 6689
Other names: Litopenaeus vannamei, P. vannamei, Pacific white shrimp, Penaeus (Litopenaeus) vannamei, Penaeus sp. AT-2008, white Pacific shrimp, white shrimp

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C7M84_000657	C7M84_001170	A0A423TW10	A0A3R7ME20	Uncharacterized protein.	P53 protein.	0.410
C7M84_000657	C7M84_006024	A0A423TW10	A0A423TG36	Uncharacterized protein.	Ataxia telangiectasia mutated; Belongs to the PI3/PI4-kinase family.	0.639
C7M84_000657	C7M84_007382	A0A423TW10	A0A3R7M7G4	Uncharacterized protein.	Putative nibrin.	0.428
C7M84_000657	C7M84_011606	A0A423TW10	A0A3R7SPV9	Uncharacterized protein.	P53 protein.	0.410
C7M84_000657	C7M84_015567	A0A423TW10	A0A3R7Q3V5	Uncharacterized protein.	Retinoblastoma family-like protein.	0.435
C7M84_000657	C7M84_023076	A0A423TW10	A0A423U4X7	Uncharacterized protein.	Putative serine/threonine-protein kinase Chk2-like; Belongs to the protein kinase superfamily.	0.440
C7M84_001170	C7M84_000657	A0A3R7ME20	A0A423TW10	P53 protein.	Uncharacterized protein.	0.410
C7M84_001170	C7M84_006024	A0A3R7ME20	A0A423TG36	P53 protein.	Ataxia telangiectasia mutated; Belongs to the PI3/PI4-kinase family.	0.858
C7M84_001170	C7M84_023076	A0A3R7ME20	A0A423U4X7	P53 protein.	Putative serine/threonine-protein kinase Chk2-like; Belongs to the protein kinase superfamily.	0.798
C7M84_001170	C7M84_024684	A0A3R7ME20	A0A423U0B0	P53 protein.	Putative cyclin-dependent kinase 5 activator 1-like.	0.554
C7M84_001170	C7M84_025556	A0A3R7ME20	A0A423TXS8	P53 protein.	Uncharacterized protein.	0.494
C7M84_001363	C7M84_024670	A0A423TTW9	A0A423U0E1	Hippo.	Putative serine/threonine-protein kinase.	0.966
C7M84_003621	C7M84_012758	A0A3R7PUU6	A0A3R7SP43	Bcl-2-related ovarian killer protein-like A.	Putative BCL2/adenovirus E1B 19 kDa protein-interacting protein.	0.604
C7M84_004718	C7M84_004719	A0A423TJP6	A0A3R7M9I8	Putative DNA-dependent protein kinase catalytic subunit-like; Belongs to the PI3/PI4-kinase family.	Putative DNA-dependent protein kinase catalytic subunit-like.	0.944
C7M84_004718	C7M84_006024	A0A423TJP6	A0A423TG36	Putative DNA-dependent protein kinase catalytic subunit-like; Belongs to the PI3/PI4-kinase family.	Ataxia telangiectasia mutated; Belongs to the PI3/PI4-kinase family.	0.620
C7M84_004718	C7M84_007382	A0A423TJP6	A0A3R7M7G4	Putative DNA-dependent protein kinase catalytic subunit-like; Belongs to the PI3/PI4-kinase family.	Putative nibrin.	0.692
C7M84_004718	C7M84_023076	A0A423TJP6	A0A423U4X7	Putative DNA-dependent protein kinase catalytic subunit-like; Belongs to the PI3/PI4-kinase family.	Putative serine/threonine-protein kinase Chk2-like; Belongs to the protein kinase superfamily.	0.510
C7M84_004719	C7M84_004718	A0A3R7M9I8	A0A423TJP6	Putative DNA-dependent protein kinase catalytic subunit-like.	Putative DNA-dependent protein kinase catalytic subunit-like; Belongs to the PI3/PI4-kinase family.	0.944
C7M84_004719	C7M84_006024	A0A3R7M9I8	A0A423TG36	Putative DNA-dependent protein kinase catalytic subunit-like.	Ataxia telangiectasia mutated; Belongs to the PI3/PI4-kinase family.	0.620
C7M84_004719	C7M84_007382	A0A3R7M9I8	A0A3R7M7G4	Putative DNA-dependent protein kinase catalytic subunit-like.	Putative nibrin.	0.692

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