STRINGSTRING
KOH24650.1 KOH24650.1 KOH24651.1 KOH24651.1 lldD lldD KOH24989.1 KOH24989.1 fadB fadB fadA fadA KOH23757.1 KOH23757.1 KOH22750.1 KOH22750.1 KOH22768.1 KOH22768.1 KOH22769.1 KOH22769.1 KOH22878.1 KOH22878.1 KOH22906.1 KOH22906.1 KOH22943.1 KOH22943.1 KOH22946.1 KOH22946.1 KOH22572.1 KOH22572.1 KOH22573.1 KOH22573.1 KOH22161.1 KOH22161.1 KOH22237.1 KOH22237.1 KOH22247.1 KOH22247.1 KOH22248.1 KOH22248.1 KOH22249.1 KOH22249.1 KOH22250.1 KOH22250.1 KOH22252.1 KOH22252.1 KOH22253.1 KOH22253.1 KOH22254.1 KOH22254.1 KOH22255.1 KOH22255.1 KOH22256.1 KOH22256.1 mmsB mmsB fabG fabG KOH22273.1 KOH22273.1 KOH22274.1 KOH22274.1 KOH22275.1 KOH22275.1 pdhA pdhA accD accD KOH22421.1 KOH22421.1 fabV fabV pgi pgi KOH21916.1 KOH21916.1 KOH21934.1 KOH21934.1 gpmI gpmI KOH21992.1 KOH21992.1 KOH21993.1 KOH21993.1 frdC frdC frdD frdD KOH22005.1 KOH22005.1 aspA-2 aspA-2 KOH22025.1 KOH22025.1 accB accB accC accC KOH21044.1 KOH21044.1 KOH21055.1 KOH21055.1 KOH21077.1 KOH21077.1 KOH21078.1 KOH21078.1 KOH21304.1 KOH21304.1 KOH21339.1 KOH21339.1 KOH21340.1 KOH21340.1 KOH21341.1 KOH21341.1 KOH21342.1 KOH21342.1 KOH21343.1 KOH21343.1 KOH21344.1 KOH21344.1 KOH21345.1 KOH21345.1 KOH21346.1 KOH21346.1 KOH21591.1 KOH21591.1 KOH21348.1 KOH21348.1 KOH21349.1 KOH21349.1 KOH21350.1 KOH21350.1 KOH21351.1 KOH21351.1 KOH21352.1 KOH21352.1 KOH21353.1 KOH21353.1 fabG-2 fabG-2 KOH21355.1 KOH21355.1 KOH21381.1 KOH21381.1 sucC sucC KOH21383.1 KOH21383.1 KOH21384.1 KOH21384.1 sdhB sdhB sdhA sdhA sdhD sdhD SdhC SdhC gltA gltA KOH21392.1 KOH21392.1 prs prs KOH21488.1 KOH21488.1 lipB lipB KOH21490.1 KOH21490.1 KOH19286.1 KOH19286.1 idnK idnK KOH19289.1 KOH19289.1 pckA pckA KOH19431.1 KOH19431.1 fbp fbp mdh mdh KOH19531.1 KOH19531.1 KOH18739.1 KOH18739.1 KOH18762.1 KOH18762.1 KOH17769.1 KOH17769.1 prpE prpE KOH17812.1 KOH17812.1 KOH17813.1 KOH17813.1 KOH17814.1 KOH17814.1 prpB prpB KOH17865.1 KOH17865.1 KOH17866.1 KOH17866.1 KOH17867.1 KOH17867.1 KOH17920.1 KOH17920.1 gabD gabD KOH17992.1 KOH17992.1 KOH18130.1 KOH18130.1 KOH18137.1 KOH18137.1 tmk tmk KOH18139.1 KOH18139.1 KOH18140.1 KOH18140.1 KOH18141.1 KOH18141.1 acpP acpP fabG-3 fabG-3 fabD fabD KOH18144.1 KOH18144.1 ackA ackA KOH18171.1 KOH18171.1 gap gap KOH18229.1 KOH18229.1 accD-2 accD-2 KOH18666.1 KOH18666.1 KOH18258.1 KOH18258.1 fadJ fadJ FadI FadI fadE fadE KOH18353.1 KOH18353.1 KOH18459.1 KOH18459.1 acnB acnB lpdA lpdA aceF aceF aceE aceE KOH18563.1 KOH18563.1 eno eno rpiA rpiA KOH18604.1 KOH18604.1 pgk pgk gapA gapA KOH18609.1 KOH18609.1 gabD-2 gabD-2 KOH17192.1 KOH17192.1 gap-2 gap-2 KOH17282.1 KOH17282.1 KOH17526.1 KOH17526.1 KOH17283.1 KOH17283.1 KOH17298.1 KOH17298.1 KOH17299.1 KOH17299.1 KOH17317.1 KOH17317.1 KOH17318.1 KOH17318.1 KOH17319.1 KOH17319.1 KOH17339.1 KOH17339.1 KOH17530.1 KOH17530.1 KOH17340.1 KOH17340.1 KOH17341.1 KOH17341.1 KOH17343.1 KOH17343.1 mmsA mmsA KOH17345.1 KOH17345.1 KOH17346.1 KOH17346.1 KOH17347.1 KOH17347.1 KOH17348.1 KOH17348.1 fabG-4 fabG-4 KOH17373.1 KOH17373.1 KOH17462.1 KOH17462.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
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gene neighborhood
gene fusions
gene co-occurrence
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co-expression
protein homology
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KOH24650.1Ketohydroxyglutarate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
KOH24651.1Ketodeoxygluconokinase; Catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate-6-phosphate from 2-dehydro-3-deoxy-D-gluconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
lldDLactate dehydrogenase; Flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
KOH24989.12-hydroxy-3-oxopropionate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
fadBMultifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (723 aa)
fadA3-ketoacyl-CoA thiolase; FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
KOH23757.1Quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
KOH22750.1Lipoate--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
KOH22768.1Phosphoenolpyruvate synthase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (278 aa)
KOH22769.1Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (789 aa)
KOH22878.14-aminobutyrate aminotransferase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
KOH22906.1Malate synthase; Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
KOH22943.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. (317 aa)
KOH22946.1Lactate dehydrogenase; Fermentative; catalyzes the formationof pyruvate from lactate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (312 aa)
KOH22572.1Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
KOH22573.1Malate synthase; Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)
KOH22161.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
KOH22237.1Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
KOH22247.1hydroxymethylglutaryl-CoA lyase; Catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
KOH22248.1Catalyzes the hydration of gamma-carboxygeranoyl-CoA to 3-hydroxy-gamma-carboxygeranoyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
KOH22249.1methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (534 aa)
KOH22250.1isovaleryl-CoA dehydrogenase; Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
KOH22252.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (408 aa)
KOH22253.1Methylmalonate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
KOH22254.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
KOH22255.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (261 aa)
KOH22256.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
mmsB3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HIBADH-related family. (300 aa)
fabG3-ketoacyl-ACP reductase; Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
KOH22273.1Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (553 aa)
KOH22274.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
KOH22275.12-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
pdhAABC transporter permease; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (364 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (289 aa)
KOH22421.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (492 aa)
fabVtrans-2-enoyl-CoA reductase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (399 aa)
pgiGlucose-6-phosphate isomerase; Functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (550 aa)
KOH21916.1Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
KOH21934.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
gpmIPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (510 aa)
KOH21992.1Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (599 aa)
KOH21993.1Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
frdCFumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (127 aa)
frdDFumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (125 aa)
KOH22005.16-phosphofructokinase; Catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
aspA-2Aspartate ammonia-lyase; Catalyzes the formation of fumarate from aspartate; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
KOH22025.1acetyl-CoA synthetase; Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (650 aa)
accBacetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (152 aa)
accCacetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
KOH21044.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1012 aa)
KOH21055.1Malate dehydrogenase; Malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; Derived by automated computational analysis using gene prediction method: Protein Homology. (562 aa)
KOH21077.1trans-2-enoyl-CoA reductase; Enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
KOH21078.1acyl-CoA dehydrogenase; Functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (760 aa)
KOH21304.1palmitoyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
KOH21339.1FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
KOH21340.1Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
KOH21341.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)
KOH21342.13-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
KOH21343.1Acyl-phosphate glycerol 3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
KOH21344.1Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)
KOH21345.1AMP-fatty acid ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa)
KOH21346.13-hydroxyacyl-ACP dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa)
KOH21591.1Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (568 aa)
KOH21348.14-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)
KOH21349.1Membrane protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (206 aa)
KOH21350.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (780 aa)
KOH21351.1Lipoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
KOH21352.13-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
KOH21353.13-hydroxydecanoyl-ACP dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
fabG-23-ketoacyl-ACP reductase; Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
KOH21355.1FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (407 aa)
KOH21381.1succinyl-CoA synthetase subunit alpha; Catalyzes the only substrate-level phosphorylation in the TCA cycle; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
sucCsuccinyl-CoA synthetase subunit beta; Catalyzes the interconversion of succinyl-CoA and succinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
KOH21383.1Dihydrolipoamide succinyltransferase; Component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
KOH21384.12-oxoglutarate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (941 aa)
sdhBPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (588 aa)
sdhDSuccinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (114 aa)
SdhCSuccinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)
gltAType II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (429 aa)
KOH21392.1Phosphoglucomutase; Catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (314 aa)
KOH21488.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0250 family. (92 aa)
lipBOctanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (220 aa)
KOH21490.1Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
KOH19286.1Phosphogluconate dehydratase; Catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (598 aa)
idnKGluconate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
KOH19289.1Ketohydroxyglutarate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
pckAPEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)
KOH19431.1Triosephosphate isomerase; Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
fbpCatalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family. (338 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (311 aa)
KOH19531.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
KOH18739.1Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa)
KOH18762.1Pyridine nucleotide transhydrogenase; Catalyzes the conversion of NADPH to NADH; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa)
KOH17769.1Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
prpECatalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (625 aa)
KOH17812.13-methylitaconate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
KOH17813.1Aconitate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (863 aa)
KOH17814.1Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
prpB2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (298 aa)
KOH17865.16-phosphogluconate dehydrogenase; Catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)
KOH17866.16-phosphogluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
KOH17867.1Glucose-6-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
KOH17920.14-aminobutyrate aminotransferase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)
gabDSuccinate-semialdehyde dehydrogenase; Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
KOH17992.1Catalyzes the formation of fumarate from malate; Derived by automated computational analysis using gene prediction method: Protein Homology. (505 aa)
KOH18130.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa)
KOH18137.1DNAse; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
tmkThymidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
KOH18139.1ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
KOH18140.14-amino-4-deoxychorismate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
KOH18141.1FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (416 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (77 aa)
fabG-33-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa)
fabDMalonyl CoA-ACP transacylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
KOH18144.13-oxoacyl-ACP synthase; FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
KOH18171.1Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. (714 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (331 aa)
KOH18229.1Aldose epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
accD-2acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (308 aa)
KOH18666.1Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (377 aa)
KOH18258.1FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (403 aa)
fadJMultifunctional fatty acid oxidation complex subunit alpha; Multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (703 aa)
FadI3-ketoacyl-CoA thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (435 aa)
fadEacyl-CoA dehydrogenase; Functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (814 aa)
KOH18353.1acetyl-CoA carboxylase subunit alpha; Catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
KOH18459.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (563 aa)
acnBBifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (865 aa)
lpdAE3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
aceFPyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (627 aa)
aceEE1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; Derived by automated computational analysis using gene prediction method: Protein Homology. (887 aa)
KOH18563.1Oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (595 aa)
enoEnolase; Catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
rpiACatalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
KOH18604.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (358 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
gapAGlyceraldehyde-3-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
KOH18609.1Transketolase; Catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology. (664 aa)
gabD-2Succinate-semialdehyde dehydrogenase; Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
KOH17192.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
gap-2Glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (477 aa)
KOH17282.13-ketoacyl-ACP reductase; Catalyzes the conversion of 3-hydroxyacyl-CoA to 3-oxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
KOH17526.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
KOH17283.1Poly(3-hydroxyalkanoate) synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (591 aa)
KOH17298.1Transketolase; Catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology. (663 aa)
KOH17299.1Transaldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
KOH17317.1Electron transfer flavoprotein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
KOH17318.1Electron transporter RnfB; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
KOH17319.1Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (545 aa)
KOH17339.1hydroxymethylglutaryl-CoA lyase; Catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
KOH17530.13-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (691 aa)
KOH17340.1methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (535 aa)
KOH17341.1isovaleryl-CoA dehydrogenase; Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
KOH17343.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
mmsAMethylmalonate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
KOH17345.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
KOH17346.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
KOH17347.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
KOH17348.13-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
fabG-43-ketoacyl-ACP reductase; Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
KOH17373.1Ribokinase; Catalyzes the formation of D-ribose 5-phosphate from ribose; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. (305 aa)
KOH17462.13-oxoacyl-ACP synthase; FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; in Pseudomonas this protein is involved in quinolone signal biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. FabH family. (364 aa)
Your Current Organism:
Vibrio parahaemolyticus
NCBI taxonomy Id: 670
Other names: ATCC 17802, Beneckea parahaemolytica, CAIM 320, CCUG 14474, CCUG 15657, CCUG 4224, CIP 75.2, DSM 10027, IFO 12711, LMG 2850, LMG:2850, NBRC 12711, NCCB 77010, NCCB 77018, NCTC 10903, NRRL B-4167, Oceanomonas parahaemolytica, Pasteurella parahaemolytica, V. parahaemolyticus
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