STRINGSTRING
plsX plsX KOH24795.1 KOH24795.1 KOH22760.1 KOH22760.1 KOH22249.1 KOH22249.1 accD accD KOH22438.1 KOH22438.1 fabV fabV KOH21950.1 KOH21950.1 accB accB accC accC KOH20936.1 KOH20936.1 KOH21077.1 KOH21077.1 KOH21342.1 KOH21342.1 KOH21344.1 KOH21344.1 KOH21346.1 KOH21346.1 KOH21352.1 KOH21352.1 KOH21355.1 KOH21355.1 KOH21490.1 KOH21490.1 fabR fabR KOH17769.1 KOH17769.1 KOH18141.1 KOH18141.1 acpP acpP fabG-3 fabG-3 fabD fabD KOH18144.1 KOH18144.1 accD-2 accD-2 KOH18258.1 KOH18258.1 KOH18353.1 KOH18353.1 fabZ fabZ KOH18561.1 KOH18561.1 KOH17222.1 KOH17222.1 KOH17340.1 KOH17340.1 KOH17462.1 KOH17462.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
plsXPhosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (341 aa)
KOH24795.1Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
KOH22760.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
KOH22249.1methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (534 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (289 aa)
KOH22438.1ACP phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
fabVtrans-2-enoyl-CoA reductase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (399 aa)
KOH21950.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
accBacetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (152 aa)
accCacetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
KOH20936.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
KOH21077.1trans-2-enoyl-CoA reductase; Enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
KOH21342.13-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
KOH21344.1Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)
KOH21346.13-hydroxyacyl-ACP dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa)
KOH21352.13-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
KOH21355.1FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (407 aa)
KOH21490.1Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
fabRTranscriptional regulator; Negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
KOH17769.1Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
KOH18141.1FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (416 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (77 aa)
fabG-33-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa)
fabDMalonyl CoA-ACP transacylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
KOH18144.13-oxoacyl-ACP synthase; FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
accD-2acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (308 aa)
KOH18258.1FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (403 aa)
KOH18353.1acetyl-CoA carboxylase subunit alpha; Catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
fabZ3-hydroxyacyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (150 aa)
KOH18561.1NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
KOH17222.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
KOH17340.1methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (535 aa)
KOH17462.13-oxoacyl-ACP synthase; FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; in Pseudomonas this protein is involved in quinolone signal biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. FabH family. (364 aa)
Your Current Organism:
Vibrio parahaemolyticus
NCBI taxonomy Id: 670
Other names: ATCC 17802, Beneckea parahaemolytica, CAIM 320, CCUG 14474, CCUG 15657, CCUG 4224, CIP 75.2, DSM 10027, IFO 12711, LMG 2850, LMG:2850, NBRC 12711, NCCB 77010, NCCB 77018, NCTC 10903, NRRL B-4167, Oceanomonas parahaemolytica, Pasteurella parahaemolytica, V. parahaemolyticus
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