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KOH18150.1 KOH18150.1 KOH17770.1 KOH17770.1 KOH19683.1 KOH19683.1 rpsT rpsT rplU rplU KOH19468.1 KOH19468.1 rpsK rpsK rpsM rpsM rplO rplO rpsE rpsE rplR rplR rplF rplF rpsH rpsH rpsN rpsN rplE rplE rplX rplX KOH19454.1 KOH19454.1 KOH19453.1 KOH19453.1 rplP rplP rpsC rpsC KOH19449.1 KOH19449.1 RpsS RpsS rplB rplB rplW rplW rplC rplC rpmE rpmE KOH19336.1 KOH19336.1 KOH21251.1 KOH21251.1 KOH21094.1 KOH21094.1 rplT rplT rsgA-2 rsgA-2 rpsG rpsG rpsF rpsF rpsR rpsR rplI rplI KOH22200.1 KOH22200.1 KOH22553.1 KOH22553.1 KOH23963.1 KOH23963.1 rplA rplA rplK rplK rsgA rsgA rnc rnc KOH18485.1 KOH18485.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KOH18150.1Ribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (1023 aa)
KOH17770.1Ribosome modulation factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (57 aa)
KOH19683.1ABC transporter ATP-binding protein; ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; Derived by automated computational analysis using gene prediction method: Protein Homology. (555 aa)
rpsT30S ribosomal protein S20; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)
rplU50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (103 aa)
KOH19468.130S ribosomal protein S4; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)
rpsK30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa)
rpsM30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (118 aa)
rplO50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (144 aa)
rpsE30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (167 aa)
rplR50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (117 aa)
rplF50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa)
rpsH30S ribosomal protein S8; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)
rpsN30S ribosomal protein S14; Located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
rplE50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa)
rplX50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (105 aa)
KOH19454.150S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome. (123 aa)
KOH19453.130S ribosomal protein S17; Derived by automated computational analysis using gene prediction method: Protein Homology. (84 aa)
rplP50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (136 aa)
rpsC30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (232 aa)
KOH19449.150S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (110 aa)
RpsS30S ribosomal protein S19; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS19 family. (92 aa)
rplB50S ribosomal protein L2; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa)
rplW50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (100 aa)
rplC50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (209 aa)
rpmE50S ribosomal protein L31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. (73 aa)
KOH19336.1GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology. (609 aa)
KOH21251.1Translation initiation factor IF-1; Derived by automated computational analysis using gene prediction method: Protein Homology. (72 aa)
KOH21094.150S ribosomal protein L25; The Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; Derived by automated computational analysis using gene prediction method: Protein Homology. (92 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (117 aa)
rsgA-2EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
rpsG30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
rpsF30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (129 aa)
rpsR30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bS18 family. (75 aa)
rplI50S ribosomal protein L9; In Escherichia coli this protein is wrapped around the base of the L1 stalk; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
KOH22200.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (97 aa)
KOH22553.123S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
KOH23963.150S ribosomal protein L10; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
rplA50S ribosomal protein L1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL1 family. (233 aa)
rplK50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (142 aa)
rsgAGTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (358 aa)
rncRibonuclease III; Cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
KOH18485.130S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa)
Your Current Organism:
Vibrio parahaemolyticus
NCBI taxonomy Id: 670
Other names: ATCC 17802, Beneckea parahaemolytica, CAIM 320, CCUG 14474, CCUG 15657, CCUG 4224, CIP 75.2, DSM 10027, IFO 12711, LMG 2850, LMG:2850, NBRC 12711, NCCB 77010, NCCB 77018, NCTC 10903, NRRL B-4167, Oceanomonas parahaemolytica, Pasteurella parahaemolytica, V. parahaemolyticus
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