STRINGSTRING
KOH18510.1 KOH18510.1 folK-2 folK-2 aceF aceF aceE aceE KOH18563.1 KOH18563.1 mutS mutS eno eno rpoE rpoE trmB trmB KOH17223.1 KOH17223.1 KOH17229.1 KOH17229.1 KOH17295.1 KOH17295.1 KOH17316.1 KOH17316.1 KOH17332.1 KOH17332.1 KOH17530.1 KOH17530.1 KOH17340.1 KOH17340.1 KOH17389.1 KOH17389.1 KOH17390.1 KOH17390.1 KOH17535.1 KOH17535.1 KOH17402.1 KOH17402.1 KOH17451.1 KOH17451.1 cobQ cobQ KOH17499.1 KOH17499.1 rimI rimI KOH18674.1 KOH18674.1 ebgA ebgA KOH18433.1 KOH18433.1 glpD glpD recD recD KOH18403.1 KOH18403.1 KOH18402.1 KOH18402.1 KOH18400.1 KOH18400.1 KOH18387.1 KOH18387.1 KOH18386.1 KOH18386.1 dnaE dnaE KOH18353.1 KOH18353.1 KOH18345.1 KOH18345.1 KOH18332.1 KOH18332.1 fliA fliA KOH18667.1 KOH18667.1 accD-2 accD-2 KOH18246.1 KOH18246.1 KOH18186.1 KOH18186.1 moaD moaD MoaE MoaE KOH18177.1 KOH18177.1 KOH18130.1 KOH18130.1 DnaE2 DnaE2 KOH18106.1 KOH18106.1 KOH18658.1 KOH18658.1 KOH18062.1 KOH18062.1 KOH18053.1 KOH18053.1 uvrC uvrC napG napG KOH25069.1 KOH25069.1 KOH24880.1 KOH24880.1 KOH24834.1 KOH24834.1 KOH24795.1 KOH24795.1 KOH24774.1 KOH24774.1 KOH24751.1 KOH24751.1 KOH24744.1 KOH24744.1 KOH24737.1 KOH24737.1 KOH24700.1 KOH24700.1 KOH24658.1 KOH24658.1 KOH24634.1 KOH24634.1 KOH24612.1 KOH24612.1 KOH24604.1 KOH24604.1 KOH24603.1 KOH24603.1 KOH25217.1 KOH25217.1 KOH25241.1 KOH25241.1 thiH thiH uvrD uvrD KOH18042.1 KOH18042.1 KOH18041.1 KOH18041.1 KOH18035.1 KOH18035.1 KOH18651.1 KOH18651.1 KOH18648.1 KOH18648.1 KOH17956.1 KOH17956.1 KOH17944.1 KOH17944.1 KOH17933.1 KOH17933.1 KOH17880.1 KOH17880.1 KOH17868.1 KOH17868.1 xerD xerD GltB GltB gltD gltD KOH19626.1 KOH19626.1 carB carB KOH19706.1 KOH19706.1 KOH19593.1 KOH19593.1 KOH19590.1 KOH19590.1 folK folK dnaG dnaG KOH19558.1 KOH19558.1 KOH19703.1 KOH19703.1 KOH19550.1 KOH19550.1 ilvH ilvH KOH19527.1 KOH19527.1 KOH19521.1 KOH19521.1 leuD leuD cysC cysC CysN CysN KOH19479.1 KOH19479.1 KOH19469.1 KOH19469.1 hslV hslV hslU hslU KOH19427.1 KOH19427.1 KOH19388.1 KOH19388.1 KOH19386.1 KOH19386.1 rph rph rpoZ rpoZ KOH19334.1 KOH19334.1 KOH19281.1 KOH19281.1 KOH19277.1 KOH19277.1 KOH20653.1 KOH20653.1 KOH20652.1 KOH20652.1 KOH20651.1 KOH20651.1 KOH20636.1 KOH20636.1 PmbA PmbA tldD tldD KOH20671.1 KOH20671.1 KOH21595.1 KOH21595.1 ribH ribH KOH21517.1 KOH21517.1 KOH21511.1 KOH21511.1 holA holA prs prs KOH21423.1 KOH21423.1 SdhC SdhC sdhA sdhA KOH21384.1 KOH21384.1 KOH21383.1 KOH21383.1 sucC sucC KOH21381.1 KOH21381.1 clpX clpX KOH21321.1 KOH21321.1 KOH21307.1 KOH21307.1 KOH21287.1 KOH21287.1 KOH21279.1 KOH21279.1 glgC-2 glgC-2 ruvC ruvC ruvA ruvA ruvB ruvB KOH21578.1 KOH21578.1 hisH hisH KOH21133.1 KOH21133.1 KOH21111.1 KOH21111.1 KOH21090.1 KOH21090.1 KOH21068.1 KOH21068.1 KOH21031.1 KOH21031.1 KOH21025.1 KOH21025.1 pheT pheT KOH20900.1 KOH20900.1 KOH20899.1 KOH20899.1 KOH20898.1 KOH20898.1 KOH20844.1 KOH20844.1 KOH20843.1 KOH20843.1 accC accC accB accB KOH22024.1 KOH22024.1 KOH22005.1 KOH22005.1 KOH21985.1 KOH21985.1 tusD tusD tusC tusC dsrH dsrH glgC glgC KOH22421.1 KOH22421.1 gcvT gcvT gcvH gcvH KOH22402.1 KOH22402.1 accD accD KOH22370.1 KOH22370.1 KOH22275.1 KOH22275.1 KOH22274.1 KOH22274.1 cyoD cyoD KOH22249.1 KOH22249.1 KOH22146.1 KOH22146.1 KOH22139.1 KOH22139.1 KOH22586.1 KOH22586.1 KOH22570.1 KOH22570.1 KOH22561.1 KOH22561.1 iscA iscA hscB hscB KOH22547.1 KOH22547.1 KOH22546.1 KOH22546.1 KOH22946.1 KOH22946.1 KOH22897.1 KOH22897.1 KOH22879.1 KOH22879.1 KOH23803.1 KOH23803.1 KOH23802.1 KOH23802.1 KOH23801.1 KOH23801.1 rnpA rnpA dnaN dnaN glyS glyS KOH23762.1 KOH23762.1 KOH23759.1 KOH23759.1 rpoC rpoC rpoB rpoB KOH24981.1 KOH24981.1 KOH18476.1 KOH18476.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KOH18510.1Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
folK-22-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)
aceFPyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (627 aa)
aceEE1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; Derived by automated computational analysis using gene prediction method: Protein Homology. (887 aa)
KOH18563.1Oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (595 aa)
mutSDNA mismatch repair protein MutS; This protein performs the mismatch recognition step during the DNA repair process; Derived by automated computational analysis using gene prediction method: Protein Homology. (853 aa)
enoEnolase; Catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
rpoERNA polymerase sigma factor RpoE; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa)
trmBtRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
KOH17223.11,4-alpha-glucan branching protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa)
KOH17229.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (675 aa)
KOH17295.1Carotenoid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
KOH17316.1Guanosine 5'-monophosphate oxidoreductase; Catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
KOH17332.14-carboxymuconolactone decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (125 aa)
KOH17530.13-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (691 aa)
KOH17340.1methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (535 aa)
KOH17389.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
KOH17390.1Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (887 aa)
KOH17535.1Nitrate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (454 aa)
KOH17402.1Anti-sigma F factor antagonist; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)
KOH17451.1Nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
cobQCobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (483 aa)
KOH17499.1Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
rimIAlanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. (151 aa)
KOH18674.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
ebgAbeta-D-galactosidase; In Escherichia coli this is the second beta-galactosidase system; Derived by automated computational analysis using gene prediction method: Protein Homology. (1032 aa)
KOH18433.1methionyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)
glpDGlycerol-3-phosphate dehydrogenase; In Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (519 aa)
recDExodeoxyribonuclease V subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (715 aa)
KOH18403.1Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
KOH18402.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
KOH18400.1Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (181 aa)
KOH18387.1DNA polymerase IV; Involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
KOH18386.1ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (641 aa)
dnaEDNA polymerase III subunit alpha; Catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1159 aa)
KOH18353.1acetyl-CoA carboxylase subunit alpha; Catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
KOH18345.13'-5' exonuclease of DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
KOH18332.1sirA-like family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family. (78 aa)
fliARNA polymerase sigma 70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (244 aa)
KOH18667.1Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
accD-2acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (308 aa)
KOH18246.1DNA polymerase III subunit gamma/tau; Derived by automated computational analysis using gene prediction method: Protein Homology. (711 aa)
KOH18186.1The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; Derived by automated computational analysis using gene prediction method: Protein Homology. (676 aa)
moaDMolybdopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (85 aa)
MoaEMolybdopterin synthase catalytic subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (151 aa)
KOH18177.1Peptide ABC transporter permease; With OppABDF is involved in the transport of oligopeptides of up to 5 amino acids into the cell; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
KOH18130.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa)
DnaE2DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1024 aa)
KOH18106.14Fe-4S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
KOH18658.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
KOH18062.1Anthranilate synthase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
KOH18053.1Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. (787 aa)
uvrCThe UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; Derived by automated computational analysis using gene prediction method: Protein Homology. (588 aa)
napGPart of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
KOH25069.1Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
KOH24880.1RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
KOH24834.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)
KOH24795.1Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
KOH24774.1NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (522 aa)
KOH24751.14-carboxymuconolactone decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
KOH24744.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)
KOH24737.1LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
KOH24700.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
KOH24658.1DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
KOH24634.1Alpha-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (896 aa)
KOH24612.1Catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (815 aa)
KOH24604.1Peptidase C69; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
KOH24603.1Zn-dependent protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)
KOH25217.1Thiamine biosynthesis protein ThiS; With ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (78 aa)
KOH25241.1Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (255 aa)
thiHIn Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
uvrDDNA-dependent helicase II; Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair; Derived by automated computational analysis using gene prediction method: Protein Homology. (724 aa)
KOH18042.1Ribonucleotide-diphosphate reductase subunit beta; B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
KOH18041.1Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the rate-limiting step in dNTP synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (760 aa)
KOH18035.14Fe-4S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
KOH18651.13'-5' exonuclease of DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
KOH18648.1Integrase; May be involved in the transfer of antibiotic resistance genes to plasmids and transposons; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
KOH17956.1Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
KOH17944.1tRNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (112 aa)
KOH17933.1Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
KOH17880.13'-5' exonuclease of DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
KOH17868.1Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
xerDSite-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
GltBGlutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1517 aa)
gltDGlutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (489 aa)
KOH19626.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
carBCarbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (1077 aa)
KOH19706.1Carbamoyl phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
KOH19593.1Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
KOH19590.1Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (586 aa)
KOH19558.1RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (620 aa)
KOH19703.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (814 aa)
KOH19550.1Restriction endonuclease EcoEI subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology. (496 aa)
ilvHAcetolactate synthase 3 regulatory subunit; With IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)
KOH19527.1Acetolactate synthase 3 catalytic subunit; Catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology. (574 aa)
KOH19521.1Isopropylmalate isomerase; Dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
leuDIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
cysCAdenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (205 aa)
CysNSulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
KOH19479.1Sulfate adenylyltransferase subunit 2; With CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
KOH19469.1DNA-directed RNA polymerase subunit alpha; Catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
hslVATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. (183 aa)
hslUATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (443 aa)
KOH19427.1Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
KOH19388.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
KOH19386.1Phosphopantothenoylcysteine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (238 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (90 aa)
KOH19334.1Nitrogen regulation protein NR; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa)
KOH19281.1DNA-directed RNA polymerase subunit sigma; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)
KOH19277.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
KOH20653.1Catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
KOH20652.1Aspartate carbamoyltransferase catalytic subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
KOH20651.1Involved in the allosteric regulation of aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (153 aa)
KOH20636.1RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living a [...] (488 aa)
PmbAProtein PmbA; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)
tldDProtease TldD; Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
KOH20671.1Excinuclease ABC subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. (940 aa)
KOH21595.1DNA-directed RNA polymerase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. (156 aa)
KOH21517.1Exodeoxyribonuclease VII small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (80 aa)
KOH21511.1Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
holADNA polymerase III subunit delta; Required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (314 aa)
KOH21423.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
SdhCSuccinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (588 aa)
KOH21384.12-oxoglutarate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (941 aa)
KOH21383.1Dihydrolipoamide succinyltransferase; Component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
sucCsuccinyl-CoA synthetase subunit beta; Catalyzes the interconversion of succinyl-CoA and succinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
KOH21381.1succinyl-CoA synthetase subunit alpha; Catalyzes the only substrate-level phosphorylation in the TCA cycle; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
clpXClp protease ClpX; Binds and unfolds substrates as part of the ClpXP protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
KOH21321.1Deoxyguanosinetriphosphate triphosphohydrolase; dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
KOH21307.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
KOH21287.1NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
KOH21279.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (169 aa)
glgC-2Glucose-1-phosphate adenylyltransferase; Catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
ruvCCrossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (173 aa)
ruvAATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (204 aa)
ruvBATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (334 aa)
KOH21578.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
hisHImidazole glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
KOH21133.1Catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (820 aa)
KOH21111.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
KOH21090.1Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (583 aa)
KOH21068.1Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
KOH21031.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0145 family. (105 aa)
KOH21025.1phenylalanine--tRNA ligase alpha subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (327 aa)
pheTphenylalanine--tRNA ligase; Catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; Derived by automated computational analysis using gene prediction method: Protein Homology. (801 aa)
KOH20900.1Dimethyl sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (815 aa)
KOH20899.1Dimethyl sulfoxide reductase; Oxidoreductase, Fe-S subunit; terminal electron transfer protein for the reduction of DMSO; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
KOH20898.1Dimethyl sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
KOH20844.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
KOH20843.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
accCacetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
accBacetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (152 aa)
KOH22024.13'-5' exonuclease of DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
KOH22005.16-phosphofructokinase; Catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
KOH21985.1Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
tusDSulfur transfer complex subunit TusD; In Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
tusCSulfur relay protein TusC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DsrF/TusC family. (118 aa)
dsrHSulfur relay protein TusB; Derived by automated computational analysis using gene prediction method: Protein Homology. (91 aa)
glgCGlucose-1-phosphate adenylyltransferase; Catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
KOH22421.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (492 aa)
gcvTGlycine cleavage system protein T; Catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
KOH22402.1Glycine dehydrogenase; Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; Derived by automated computational analysis using gene prediction method: Protein Homology. (954 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (289 aa)
KOH22370.1Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
KOH22275.12-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
KOH22274.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
cyoDCytochrome O ubiquinol oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (103 aa)
KOH22249.1methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (534 aa)
KOH22146.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1422 aa)
KOH22139.1Spermidine acetyltransferase; Catalyzes the formation of N(1)- and N(8)-acetylspermidine from spermidine; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
KOH22586.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (84 aa)
KOH22570.1Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
KOH22561.1Scaffolding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (127 aa)
iscAForms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (107 aa)
hscBCobalamin 5'-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HscB family. (171 aa)
KOH22547.1DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (75 aa)
KOH22546.1Exodeoxyribonuclease VII large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
KOH22946.1Lactate dehydrogenase; Fermentative; catalyzes the formationof pyruvate from lactate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (312 aa)
KOH22897.1DeoR faimly transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
KOH22879.1Catalyzes the degradation of phosphonoacetaldehyde to acetaldehyde and phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
KOH23803.1Among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function; Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
KOH23802.1Acetolactate synthase catalytic subunit; Catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa)
KOH23801.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
rnpARibonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (118 aa)
dnaNDNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (366 aa)
glySglycine-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (688 aa)
KOH23762.1glycyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
KOH23759.1Sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (82 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1400 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (1342 aa)
KOH24981.1Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
KOH18476.1DNA polymerase III subunit psi; With the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)
Your Current Organism:
Vibrio parahaemolyticus
NCBI taxonomy Id: 670
Other names: ATCC 17802, Beneckea parahaemolytica, CAIM 320, CCUG 14474, CCUG 15657, CCUG 4224, CIP 75.2, DSM 10027, IFO 12711, LMG 2850, LMG:2850, NBRC 12711, NCCB 77010, NCCB 77018, NCTC 10903, NRRL B-4167, Oceanomonas parahaemolytica, Pasteurella parahaemolytica, V. parahaemolyticus
Server load: low (20%) [HD]