STRINGSTRING
KOH24612.1 KOH24612.1 KOH24613.1 KOH24613.1 KOH24622.1 KOH24622.1 KOH24650.1 KOH24650.1 KOH24651.1 KOH24651.1 KOH24661.1 KOH24661.1 fghA fghA pdxH pdxH araD araD KOH24791.1 KOH24791.1 KOH24849.1 KOH24849.1 KOH24869.1 KOH24869.1 KOH24984.1 KOH24984.1 KOH24987.1 KOH24987.1 KOH23987.1 KOH23987.1 fadB fadB fadA fadA KOH22757.1 KOH22757.1 KOH22769.1 KOH22769.1 KOH22827.1 KOH22827.1 KOH22877.1 KOH22877.1 KOH22878.1 KOH22878.1 KOH22879.1 KOH22879.1 cmtB cmtB KOH22882.1 KOH22882.1 KOH22883.1 KOH22883.1 KOH22906.1 KOH22906.1 KOH22913.1 KOH22913.1 KOH22943.1 KOH22943.1 KOH22946.1 KOH22946.1 KOH22572.1 KOH22572.1 KOH22573.1 KOH22573.1 KOH22146.1 KOH22146.1 KOH22161.1 KOH22161.1 KOH22211.1 KOH22211.1 KOH22252.1 KOH22252.1 KOH22274.1 KOH22274.1 KOH22275.1 KOH22275.1 pdhA pdhA mgsA mgsA KOH22372.1 KOH22372.1 KOH22378.1 KOH22378.1 accD accD KOH22421.1 KOH22421.1 KOH22431.1 KOH22431.1 fabV fabV cysH cysH cysJ cysJ pgi pgi KOH21916.1 KOH21916.1 metF metF KOH21934.1 KOH21934.1 KOH21952.1 KOH21952.1 argD argD gpmI gpmI cysE cysE KOH21992.1 KOH21992.1 KOH21993.1 KOH21993.1 frdC frdC frdD frdD KOH22005.1 KOH22005.1 aspA-2 aspA-2 KOH22025.1 KOH22025.1 accB accB accC accC KOH20843.1 KOH20843.1 KOH20844.1 KOH20844.1 KOH20845.1 KOH20845.1 KOH20972.1 KOH20972.1 KOH20973.1 KOH20973.1 KOH20974.1 KOH20974.1 KOH21066.1 KOH21066.1 KOH21077.1 KOH21077.1 KOH21102.1 KOH21102.1 KOH21103.1 KOH21103.1 KOH21133.1 KOH21133.1 KOH21576.1 KOH21576.1 KOH21240.1 KOH21240.1 KOH21256.1 KOH21256.1 KOH21307.1 KOH21307.1 KOH21357.1 KOH21357.1 KOH21381.1 KOH21381.1 sucC sucC KOH21383.1 KOH21383.1 KOH21384.1 KOH21384.1 sdhB sdhB sdhA sdhA sdhD sdhD SdhC SdhC gltA gltA KOH21392.1 KOH21392.1 KOH21423.1 KOH21423.1 gltX gltX hemA hemA prs prs glyA glyA KOH20602.1 KOH20602.1 KOH20629.1 KOH20629.1 KOH19286.1 KOH19286.1 idnK idnK KOH19289.1 KOH19289.1 hemB hemB glnA glnA pckA pckA cysQ cysQ KOH19431.1 KOH19431.1 KOH19432.1 KOH19432.1 glpX glpX KOH19478.1 KOH19478.1 KOH19479.1 KOH19479.1 CysN CysN cysC cysC fbp fbp ubiX ubiX mdh mdh KOH19531.1 KOH19531.1 dapB dapB KOH19626.1 KOH19626.1 gltD gltD GltB GltB thrA thrA thrB thrB KOH19639.1 KOH19639.1 KOH18722.1 KOH18722.1 hemC hemC KOH18727.1 KOH18727.1 dapF dapF KOH18739.1 KOH18739.1 KOH18753.1 KOH18753.1 KOH17788.1 KOH17788.1 KOH17796.1 KOH17796.1 KOH17861.1 KOH17861.1 KOH17865.1 KOH17865.1 KOH17866.1 KOH17866.1 KOH17867.1 KOH17867.1 KOH17876.1 KOH17876.1 KOH17877.1 KOH17877.1 ectA ectA KOH17920.1 KOH17920.1 gabD gabD KOH17992.1 KOH17992.1 nrfA nrfA KOH18049.1 KOH18049.1 KOH18106.1 KOH18106.1 KOH18108.1 KOH18108.1 KOH18130.1 KOH18130.1 ackA ackA KOH18171.1 KOH18171.1 KOH18203.1 KOH18203.1 asd asd gap gap KOH18229.1 KOH18229.1 accD-2 accD-2 KOH18257.1 KOH18257.1 fadJ fadJ FadI FadI KOH18324.1 KOH18324.1 dapA dapA KOH18353.1 KOH18353.1 KOH18422.1 KOH18422.1 galM galM serB serB KOH18505.1 KOH18505.1 acnB acnB lpdA lpdA aceF aceF aceE aceE KOH18562.1 KOH18562.1 KOH18566.1 KOH18566.1 eno eno rpiA rpiA KOH18599.1 KOH18599.1 KOH18604.1 KOH18604.1 pgk pgk KOH18609.1 KOH18609.1 gabD-2 gabD-2 gap-2 gap-2 KOH17282.1 KOH17282.1 KOH17526.1 KOH17526.1 KOH17527.1 KOH17527.1 KOH17285.1 KOH17285.1 KOH17298.1 KOH17298.1 KOH17299.1 KOH17299.1 KOH17332.1 KOH17332.1 KOH17343.1 KOH17343.1 KOH17531.1 KOH17531.1 KOH17390.1 KOH17390.1 KOH17393.1 KOH17393.1 KOH17429.1 KOH17429.1 KOH17446.1 KOH17446.1 nirD nirD cobA-2 cobA-2
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
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gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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KOH24612.1Catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (815 aa)
KOH24613.1Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
KOH24622.1Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
KOH24650.1Ketohydroxyglutarate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
KOH24651.1Ketodeoxygluconokinase; Catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate-6-phosphate from 2-dehydro-3-deoxy-D-gluconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
KOH24661.1Catalyzes the formation of S-formylglutathione from S-(hydroxymethyl)glutathione; also catalyzes the formation of aldehyde or ketone from alcohols; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (382 aa)
fghAS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (279 aa)
pdxHPyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (211 aa)
araDCatalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
KOH24791.1Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
KOH24849.1Dihydropteridine reductase; Catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
KOH24869.1Formate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (807 aa)
KOH24984.1PTS fructose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (635 aa)
KOH24987.1PTS fructose transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (100 aa)
KOH23987.1Lysine decarboxylase LdcC; Constitutive; catalyzes the formation of cadaverine from lysine; Derived by automated computational analysis using gene prediction method: Protein Homology. (711 aa)
fadBMultifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (723 aa)
fadA3-ketoacyl-CoA thiolase; FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
KOH22757.1N-ethylmaleimide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
KOH22769.1Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (789 aa)
KOH22827.1PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
KOH22877.12-aminoethylphosphonate--pyruvate aminotransferase; Catalyzes the formation of phosphonoacetaldehyde from 2-aminoethylphosphonate and pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
KOH22878.14-aminobutyrate aminotransferase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
KOH22879.1Catalyzes the degradation of phosphonoacetaldehyde to acetaldehyde and phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
cmtBPTS system mannitol-specific transporter subunit IIA; TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
KOH22882.1PTS ascorbate transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (95 aa)
KOH22883.1PTS beta-glucoside transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
KOH22906.1Malate synthase; Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
KOH22913.1Hydroxyglutarate oxidase; Catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
KOH22943.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. (317 aa)
KOH22946.1Lactate dehydrogenase; Fermentative; catalyzes the formationof pyruvate from lactate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (312 aa)
KOH22572.1Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
KOH22573.1Malate synthase; Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)
KOH22146.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1422 aa)
KOH22161.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
KOH22211.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
KOH22252.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (408 aa)
KOH22274.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
KOH22275.12-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
pdhAABC transporter permease; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (364 aa)
mgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (151 aa)
KOH22372.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)
KOH22378.1N-ethylmaleimide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (289 aa)
KOH22421.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (492 aa)
KOH22431.1Formate--tetrahydrofolate ligase; Catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; Derived by automated computational analysis using gene prediction method: Protein Homology. (582 aa)
fabVtrans-2-enoyl-CoA reductase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (399 aa)
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (259 aa)
cysJSulfite reductase subunit alpha; Catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (623 aa)
pgiGlucose-6-phosphate isomerase; Functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (550 aa)
KOH21916.1Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
metFMTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (300 aa)
KOH21934.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
KOH21952.1Phosphoribulokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
argDAcetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (403 aa)
gpmIPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (510 aa)
cysECatalyzes the O-acetylation of serine; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
KOH21992.1Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (599 aa)
KOH21993.1Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
frdCFumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (127 aa)
frdDFumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (125 aa)
KOH22005.16-phosphofructokinase; Catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
aspA-2Aspartate ammonia-lyase; Catalyzes the formation of fumarate from aspartate; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
KOH22025.1acetyl-CoA synthetase; Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (650 aa)
accBacetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (152 aa)
accCacetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
KOH20843.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
KOH20844.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
KOH20845.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (951 aa)
KOH20972.1Maleylacetoacetate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
KOH20973.12-keto-4-pentenoate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
KOH20974.1Dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
KOH21066.1MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
KOH21077.1trans-2-enoyl-CoA reductase; Enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
KOH21102.1Thiosulfate sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
KOH21103.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (598 aa)
KOH21133.1Catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (820 aa)
KOH21576.1Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
KOH21240.1Molecular chaperone TorD; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
KOH21256.1Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (741 aa)
KOH21307.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
KOH21357.1Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
KOH21381.1succinyl-CoA synthetase subunit alpha; Catalyzes the only substrate-level phosphorylation in the TCA cycle; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
sucCsuccinyl-CoA synthetase subunit beta; Catalyzes the interconversion of succinyl-CoA and succinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
KOH21383.1Dihydrolipoamide succinyltransferase; Component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
KOH21384.12-oxoglutarate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (941 aa)
sdhBPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (588 aa)
sdhDSuccinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (114 aa)
SdhCSuccinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)
gltAType II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (429 aa)
KOH21392.1Phosphoglucomutase; Catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa)
KOH21423.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (474 aa)
hemAglutamyl-tRNA reductase; Catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (314 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa)
KOH20602.1Alanine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
KOH20629.1Glycerate dehydrogenase; Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (320 aa)
KOH19286.1Phosphogluconate dehydratase; Catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (598 aa)
idnKGluconate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
KOH19289.1Ketohydroxyglutarate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
hemBDelta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (353 aa)
glnAForms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
pckAPEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)
cysQ3'-5'-bisphosphate nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
KOH19431.1Triosephosphate isomerase; Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
KOH19432.15-carboxymethyl-2-hydroxymuconate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (115 aa)
glpXFructose 1,6-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
KOH19478.1uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
KOH19479.1Sulfate adenylyltransferase subunit 2; With CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
CysNSulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
cysCAdenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (205 aa)
fbpCatalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family. (338 aa)
ubiXAromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (212 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (311 aa)
KOH19531.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (269 aa)
KOH19626.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
gltDGlutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (489 aa)
GltBGlutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1517 aa)
thrAAspartate kinase; Multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; Derived by automated computational analysis using gene prediction method: Protein Homology. (819 aa)
thrBSerine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (318 aa)
KOH19639.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
KOH18722.1uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (312 aa)
KOH18727.1Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
dapFInvolved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
KOH18739.1Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa)
KOH18753.1Thiosulfate sulfurtransferase; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide. (106 aa)
KOH17788.1Ferrochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
KOH17796.1Acylphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (90 aa)
KOH17861.1Catalyzes the oxidation of acetaldehyde, benzaldehyde, propionaldehyde and other aldehydes; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
KOH17865.16-phosphogluconate dehydrogenase; Catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)
KOH17866.16-phosphogluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
KOH17867.1Glucose-6-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
KOH17876.1Ectoine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa)
KOH17877.1Diaminobutyrate--2-oxoglutarate aminotransferase; Catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde; Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa)
ectA2,4-diaminobutyric acid acetyltransferase; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A. (177 aa)
KOH17920.14-aminobutyrate aminotransferase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)
gabDSuccinate-semialdehyde dehydrogenase; Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
KOH17992.1Catalyzes the formation of fumarate from malate; Derived by automated computational analysis using gene prediction method: Protein Homology. (505 aa)
nrfACatalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
KOH18049.1Aminotransferase class III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (958 aa)
KOH18106.14Fe-4S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
KOH18108.1Tetrathionate reductase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. (1030 aa)
KOH18130.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
KOH18171.1Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. (714 aa)
KOH18203.1Acetaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (900 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (371 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (331 aa)
KOH18229.1Aldose epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
accD-2acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (308 aa)
KOH18257.1Aspartate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
fadJMultifunctional fatty acid oxidation complex subunit alpha; Multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (703 aa)
FadI3-ketoacyl-CoA thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (435 aa)
KOH18324.1dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa)
KOH18353.1acetyl-CoA carboxylase subunit alpha; Catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
KOH18422.12,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
galMGalactose-1-epimerase; Mutarotase; catalyzes the conversion of beta-galactose to the alpha-anomer; links the metabolism of lactose and galactose; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
serBPhosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
KOH18505.1Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
acnBBifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (865 aa)
lpdAE3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
aceFPyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (627 aa)
aceEE1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; Derived by automated computational analysis using gene prediction method: Protein Homology. (887 aa)
KOH18562.1glutaconyl-CoA decarboxylase subunit beta; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the GcdB/MmdB/OadB family. (376 aa)
KOH18566.1Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
enoEnolase; Catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
rpiACatalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
KOH18599.1D-3-phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
KOH18604.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (358 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
KOH18609.1Transketolase; Catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology. (664 aa)
gabD-2Succinate-semialdehyde dehydrogenase; Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
gap-2Glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (477 aa)
KOH17282.13-ketoacyl-ACP reductase; Catalyzes the conversion of 3-hydroxyacyl-CoA to 3-oxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
KOH17526.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
KOH17527.1Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (151 aa)
KOH17285.1Nitrate reductase; Periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; Derived by automated computational analysis using gene prediction method: Protein Homology. (829 aa)
KOH17298.1Transketolase; Catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology. (663 aa)
KOH17299.1Transaldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
KOH17332.14-carboxymuconolactone decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (125 aa)
KOH17343.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
KOH17531.1Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
KOH17390.1Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (887 aa)
KOH17393.1Dienelactone hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
KOH17429.1Threonine aldolase; Low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
KOH17446.1Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (854 aa)
nirDInvolved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; Derived by automated computational analysis using gene prediction method: Protein Homology. (107 aa)
cobA-2uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. (252 aa)
Your Current Organism:
Vibrio parahaemolyticus
NCBI taxonomy Id: 670
Other names: ATCC 17802, Beneckea parahaemolytica, CAIM 320, CCUG 14474, CCUG 15657, CCUG 4224, CIP 75.2, DSM 10027, IFO 12711, LMG 2850, LMG:2850, NBRC 12711, NCCB 77010, NCCB 77018, NCTC 10903, NRRL B-4167, Oceanomonas parahaemolytica, Pasteurella parahaemolytica, V. parahaemolyticus
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