STRINGSTRING
TM35_000381970 TM35_000381970 TM35_000371780 TM35_000371780 TM35_000371210 TM35_000371210 TM35_000341470 TM35_000341470 TM35_000342010 TM35_000342010 TM35_000321650 TM35_000321650 TM35_000271550 TM35_000271550 TM35_000272350 TM35_000272350 TM35_000261560 TM35_000261560 TM35_000251330 TM35_000251330 TM35_000252120 TM35_000252120 TM35_000241250 TM35_000241250 TM35_000241950 TM35_000241950 TM35_000241710 TM35_000241710 TM35_000222660 TM35_000222660 TM35_000211830 TM35_000211830 TM35_000182250 TM35_000182250 TM35_000011170 TM35_000011170 TM35_000011160 TM35_000011160 TM35_000202390 TM35_000202390 TM35_000152280 TM35_000152280 TM35_000151090 TM35_000151090 TM35_000142920 TM35_000142920 TM35_000131350 TM35_000131350 TM35_000132490 TM35_000132490 TM35_000111290 TM35_000111290 TM35_000111810 TM35_000111810 TM35_000112160 TM35_000112160 TM35_000121340 TM35_000121340 TM35_000101440 TM35_000101440 TM35_000101640 TM35_000101640 TM35_000102060 TM35_000102060 TM35_000093160 TM35_000093160 TM35_000071400 TM35_000071400 TM35_000084160 TM35_000084160 TM35_000071910 TM35_000071910 TM35_000084710 TM35_000084710 TM35_000431640 TM35_000431640 TM35_000441670 TM35_000441670 TM35_000891030 TM35_000891030 TM35_000891020 TM35_000891020 TM35_002821000 TM35_002821000 TM35_000011060 TM35_000011060 pfk pfk TM35_000022560 TM35_000022560 TM35_000024090 TM35_000024090 TM35_000011080 TM35_000011080 TM35_000011490 TM35_000011490 TM35_000033930 TM35_000033930 TM35_000034960 TM35_000034960 TM35_000034120 TM35_000034120 TM35_000034460 TM35_000034460 TM35_000033420 TM35_000033420 TM35_000022600 TM35_000022600 TM35_000034840 TM35_000034840 TM35_000032160 TM35_000032160 TM35_000043430 TM35_000043430 TM35_000041940 TM35_000041940 TM35_000043070 TM35_000043070 TM35_000073890 TM35_000073890 TM35_000044920 TM35_000044920 TM35_000042670 TM35_000042670 TM35_000053860 TM35_000053860 TM35_000052560 TM35_000052560 TM35_000054600 TM35_000054600 TM35_000053680 TM35_000053680 TM35_000052070 TM35_000052070 TM35_000051740 TM35_000051740 TM35_000052700 TM35_000052700 TM35_000064220 TM35_000064220 TM35_000014560 TM35_000014560
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TM35_000381970NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (483 aa)
TM35_000371780Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (417 aa)
TM35_000371210Putative cytochrome c1, heme protein, mitochondrial. (258 aa)
TM35_0003414702,3-bisphosphoglycerate-independent phosphoglycerate mutase. (553 aa)
TM35_000342010Glycerol dehydrogenase. (383 aa)
TM35_000321650Glucose-6-phosphate isomerase; Belongs to the GPI family. (607 aa)
TM35_000271550Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (564 aa)
TM35_000272350Putative fructose-bisphosphate aldolase glycosomal. (362 aa)
TM35_000261560Uncharacterized protein. (549 aa)
TM35_000251330Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
TM35_000252120Carrier protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (385 aa)
TM35_000241250Malate dehydrogenase. (330 aa)
TM35_000241950Putative 2,3-bisphosphoglycerate-independent phosphoglycerate mutase. (762 aa)
TM35_0002417102-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase. (388 aa)
TM35_000222660Enolase. (547 aa)
TM35_000211830Putative electron transfer protein. (180 aa)
TM35_000182250Succinate dehydrogenase. (195 aa)
TM35_000011170Malate dehydrogenase. (317 aa)
TM35_000011160Malate dehydrogenase. (363 aa)
TM35_000202390NADH-ubiquinone oxidoreductase, mitochondrial. (258 aa)
TM35_000152280Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (609 aa)
TM35_000151090Triosephosphate isomerase. (258 aa)
TM35_000142920Phosphoglycerate kinase. (503 aa)
TM35_000131350Electron transfer protein. (241 aa)
TM35_0001324906-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (268 aa)
TM35_000111290Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (303 aa)
TM35_000111810Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (347 aa)
TM35_000112160Putative electron-transfer-flavoprotein, alpha polypeptide. (321 aa)
TM35_000121340Phosphotransferase. (471 aa)
TM35_000101440Putative cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (114 aa)
TM35_000101640Putative coenzyme Q-binding protein COQ10 B, mitochondrial-like. (421 aa)
TM35_000102060Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (356 aa)
TM35_000093160Fumarate hydratase. (557 aa)
TM35_000071400Phosphoglycerate kinase. (527 aa)
TM35_000084160Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (249 aa)
TM35_000071910Glyceraldehyde-3-phosphate dehydrogenase. (359 aa)
TM35_0000847106-phosphogluconolactonase. (137 aa)
TM35_000431640Fumarate hydratase. (555 aa)
TM35_000441670Succinyl-coa:3-ketoacid-coenzyme a transferase-like protein. (497 aa)
TM35_000891030Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (121 aa)
TM35_000891020Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (123 aa)
TM35_002821000Phosphoglycerate kinase. (401 aa)
TM35_000011060Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (566 aa)
pfkATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (485 aa)
TM35_000022560Glyceraldehyde-3-phosphate dehydrogenase. (332 aa)
TM35_000024090Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (372 aa)
TM35_000011080Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (566 aa)
TM35_000011490Enolase. (429 aa)
TM35_000033930Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (898 aa)
TM35_000034960Electron transfer protein. (297 aa)
TM35_000034120Citrate synthase; Belongs to the citrate synthase family. (471 aa)
TM35_000034460UTP--glucose-1-phosphate uridylyltransferase. (487 aa)
TM35_000033420Pyruvate kinase; Belongs to the pyruvate kinase family. (499 aa)
TM35_000022600Uncharacterized protein. (90 aa)
TM35_000034840Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (378 aa)
TM35_000032160Putative glycosomal malate dehydrogenase; Belongs to the LDH/MDH superfamily. (323 aa)
TM35_0000434306-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (479 aa)
TM35_000041940Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (347 aa)
TM35_000043070Ribulose-phosphate 3-epimerase. (219 aa)
TM35_000073890Uncharacterized protein. (147 aa)
TM35_000044920Reiske iron-sulfur protein. (297 aa)
TM35_000042670TPR domain protein. (345 aa)
TM35_000053860Rac serine-threonine kinase. (636 aa)
TM35_000052560NADH-ubiquinone oxidoreductase 20 kDa subunit, mitochondrial; Belongs to the complex I 20 kDa subunit family. (202 aa)
TM35_000054600Putative electron transfer flavoprotein. (268 aa)
TM35_000053680Phosphoglycerate kinase. (897 aa)
TM35_000052070Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
TM35_000051740Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (494 aa)
TM35_0000527002-oxoglutarate dehydrogenase subunit. (1010 aa)
TM35_0000642202-oxoglutarate dehydrogenase E1 component. (1009 aa)
TM35_000014560Putative hydroxymethylglutaryl-CoA lyase, putative,3-hydroxy-3-methylglutarate-CoA lyase. (428 aa)
Your Current Organism:
Trypanosoma theileri
NCBI taxonomy Id: 67003
Other names: T. theileri
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.