25 items (Trypanosoma theileri) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	TM35_000014980	Putative G-actin binding protein, putative,twinfilin. (340 aa)
	TM35_000421620	3-hydroxyacyl-CoA dehydrogenase. (1078 aa)
	TM35_000411770	Protein kinase domain-containing protein. (1303 aa)
	TM35_000351180	Putative rho-like GTP binding protein. (263 aa)
	TM35_000351510	Putative WAS protein family 3-like. (600 aa)
	TM35_000371130	Formin 2 (FH2) domain protein. (961 aa)
	TM35_000351230	Uncharacterized protein. (1227 aa)
	TM35_000252080	Uncharacterized protein. (647 aa)
	TM35_000252100	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (355 aa)
	TM35_000211640	Uncharacterized protein. (966 aa)
	TM35_000181560	Uncharacterized protein. (703 aa)
	TM35_000182560	Actin-related protein 3; Belongs to the actin family. (416 aa)
	TM35_000141130	F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (486 aa)
	TM35_000131660	Coronin. (529 aa)
	TM35_000091550	Cofilin/actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (138 aa)
	TM35_000112230	Uncharacterized protein. (762 aa)
	TM35_000093360	WD40 repeat-containing protein. (604 aa)
	TM35_000092180	Uncharacterized protein. (1017 aa)
	TM35_000082410	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (99 aa)
	TM35_000053600	WASH complex subunit strumpellin. (1203 aa)
	TM35_000032390	Uncharacterized protein. (257 aa)
	TM35_000031440	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
	TM35_000034380	Putative ARP2/3 complex subunit. (384 aa)
	TM35_000021300	Uncharacterized protein. (592 aa)
	TM35_000025300	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (181 aa)

Your Current Organism:

Trypanosoma theileri

NCBI taxonomy Id: 67003
Other names: T. theileri

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TM35_000014980	TM35_000021300	A0A1X0P9W3	A0A1X0P796	Putative G-actin binding protein, putative,twinfilin.	Uncharacterized protein.	0.707
TM35_000014980	TM35_000031440	A0A1X0P9W3	A0A1X0P6E4	Putative G-actin binding protein, putative,twinfilin.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.659
TM35_000014980	TM35_000034380	A0A1X0P9W3	A0A1X0P764	Putative G-actin binding protein, putative,twinfilin.	Putative ARP2/3 complex subunit.	0.438
TM35_000014980	TM35_000091550	A0A1X0P9W3	A0A1X0NZK0	Putative G-actin binding protein, putative,twinfilin.	Cofilin/actin depolymerizing factor; Belongs to the actin-binding proteins ADF family.	0.667
TM35_000014980	TM35_000093360	A0A1X0P9W3	A0A1X0P016	Putative G-actin binding protein, putative,twinfilin.	WD40 repeat-containing protein.	0.527
TM35_000014980	TM35_000131660	A0A1X0P9W3	A0A1X0NWV5	Putative G-actin binding protein, putative,twinfilin.	Coronin.	0.515
TM35_000014980	TM35_000141130	A0A1X0P9W3	A0A1X0NW42	Putative G-actin binding protein, putative,twinfilin.	F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.949
TM35_000014980	TM35_000182560	A0A1X0P9W3	A0A1X0NVG9	Putative G-actin binding protein, putative,twinfilin.	Actin-related protein 3; Belongs to the actin family.	0.538
TM35_000014980	TM35_000351180	A0A1X0P9W3	A0A1X0NKS6	Putative G-actin binding protein, putative,twinfilin.	Putative rho-like GTP binding protein.	0.707
TM35_000021300	TM35_000014980	A0A1X0P796	A0A1X0P9W3	Uncharacterized protein.	Putative G-actin binding protein, putative,twinfilin.	0.707
TM35_000021300	TM35_000025300	A0A1X0P796	A0A1X0P8E0	Uncharacterized protein.	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.613
TM35_000021300	TM35_000031440	A0A1X0P796	A0A1X0P6E4	Uncharacterized protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.739
TM35_000021300	TM35_000034380	A0A1X0P796	A0A1X0P764	Uncharacterized protein.	Putative ARP2/3 complex subunit.	0.725
TM35_000021300	TM35_000082410	A0A1X0P796	A0A1X0P160	Uncharacterized protein.	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.	0.619
TM35_000021300	TM35_000091550	A0A1X0P796	A0A1X0NZK0	Uncharacterized protein.	Cofilin/actin depolymerizing factor; Belongs to the actin-binding proteins ADF family.	0.488
TM35_000021300	TM35_000141130	A0A1X0P796	A0A1X0NW42	Uncharacterized protein.	F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.646
TM35_000021300	TM35_000181560	A0A1X0P796	A0A1X0NV64	Uncharacterized protein.	Uncharacterized protein.	0.830
TM35_000021300	TM35_000182560	A0A1X0P796	A0A1X0NVG9	Uncharacterized protein.	Actin-related protein 3; Belongs to the actin family.	0.726
TM35_000021300	TM35_000211640	A0A1X0P796	A0A1X0NSN6	Uncharacterized protein.	Uncharacterized protein.	0.762
TM35_000021300	TM35_000252080	A0A1X0P796	A0A1X0NQB6	Uncharacterized protein.	Uncharacterized protein.	0.830