STRINGSTRING
TM35_000082250 TM35_000082250 TM35_003131000 TM35_003131000 TM35_000791060 TM35_000791060 TM35_000721050 TM35_000721050 TM35_000721060 TM35_000721060 TM35_000631030 TM35_000631030 TM35_000721130 TM35_000721130 TM35_000461310 TM35_000461310 TM35_000481220 TM35_000481220 TM35_000491140 TM35_000491140 TM35_000431750 TM35_000431750 TM35_000401090 TM35_000401090 TM35_000401310 TM35_000401310 TM35_000401790 TM35_000401790 TM35_000401720 TM35_000401720 TM35_000391390 TM35_000391390 TM35_000391790 TM35_000391790 TM35_000451680 TM35_000451680 TM35_000441650 TM35_000441650 TM35_000401650 TM35_000401650 TM35_000391650 TM35_000391650 TM35_000431780 TM35_000431780 TM35_000381330 TM35_000381330 TM35_000411090 TM35_000411090 TM35_000361360 TM35_000361360 TM35_000371260 TM35_000371260 TM35_000341640 TM35_000341640 FEN1 FEN1 TM35_000332090 TM35_000332090 TM35_000332020 TM35_000332020 TM35_000332030 TM35_000332030 TM35_000371930 TM35_000371930 TM35_000332180 TM35_000332180 TM35_000341410 TM35_000341410 TM35_000341620 TM35_000341620 TM35_000301640 TM35_000301640 TM35_000291740 TM35_000291740 TM35_000291670 TM35_000291670 TM35_000302030 TM35_000302030 TM35_000281700 TM35_000281700 TM35_000281980 TM35_000281980 NTH1 NTH1 TM35_000292350 TM35_000292350 TM35_000281990 TM35_000281990 TM35_000261960 TM35_000261960 TM35_000251380 TM35_000251380 TM35_000281360 TM35_000281360 TM35_000251340 TM35_000251340 TM35_000251390 TM35_000251390 TM35_000242460 TM35_000242460 TM35_000241380 TM35_000241380 TM35_000231630 TM35_000231630 TM35_000242080 TM35_000242080 TM35_000232050 TM35_000232050 TM35_000232380 TM35_000232380 TM35_000251850 TM35_000251850 TM35_000232040 TM35_000232040 TM35_000222830 TM35_000222830 TM35_000241490 TM35_000241490 TM35_000211480 TM35_000211480 TM35_000221970 TM35_000221970 TM35_000211470 TM35_000211470 TM35_000212550 TM35_000212550 TM35_000182630 TM35_000182630 TM35_000172070 TM35_000172070 TM35_000172380 TM35_000172380 TM35_000172130 TM35_000172130 TM35_000173060 TM35_000173060 TM35_000191040 TM35_000191040 TM35_000173170 TM35_000173170 TM35_000172350 TM35_000172350 TM35_000162320 TM35_000162320 TM35_000172850 TM35_000172850 TM35_000151130 TM35_000151130 TM35_000182660 TM35_000182660 TM35_000151230 TM35_000151230 TM35_000171610 TM35_000171610 TM35_000152160 TM35_000152160 TM35_000152670 TM35_000152670 TM35_000152660 TM35_000152660 TM35_000152120 TM35_000152120 TM35_000151990 TM35_000151990 TM35_000153090 TM35_000153090 TM35_000141920 TM35_000141920 TM35_000142970 TM35_000142970 TM35_000131380 TM35_000131380 TM35_000162770 TM35_000162770 TM35_000162870 TM35_000162870 TM35_000131050 TM35_000131050 TM35_000133010 TM35_000133010 TM35_000152400 TM35_000152400 TM35_000131520 TM35_000131520 TM35_000121210 TM35_000121210 TM35_000141300 TM35_000141300 TM35_000111200 TM35_000111200 TM35_000111390 TM35_000111390 TM35_000131440 TM35_000131440 TM35_000112600 TM35_000112600 TM35_000112900 TM35_000112900 TM35_000112880 TM35_000112880 TM35_000113400 TM35_000113400 TM35_000113420 TM35_000113420 TM35_000113470 TM35_000113470 TM35_000101990 TM35_000101990 TM35_000091160 TM35_000091160 TM35_000102260 TM35_000102260 TM35_000092720 TM35_000092720 TM35_000091630 TM35_000091630 TM35_000091490 TM35_000091490 TM35_000083330 TM35_000083330 TM35_000071500 TM35_000071500 TM35_000082810 TM35_000082810 TM35_000084560 TM35_000084560 TM35_000092900 TM35_000092900 TM35_000071050 TM35_000071050 TM35_000072480 TM35_000072480 TM35_000072690 TM35_000072690 TM35_000074980 TM35_000074980 TM35_000061310 TM35_000061310 TM35_000062320 TM35_000062320 TM35_000071140 TM35_000071140 TM35_000071340 TM35_000071340 TM35_000074770 TM35_000074770 TM35_000072340 TM35_000072340 TM35_000064870 TM35_000064870 TM35_000064830 TM35_000064830 TM35_000062340 TM35_000062340 TM35_000052120 TM35_000052120 TM35_000054330 TM35_000054330 TM35_000054580 TM35_000054580 TM35_000042380 TM35_000042380 TM35_000054090 TM35_000054090 TM35_000043160 TM35_000043160 TM35_000043310 TM35_000043310 TM35_000053450 TM35_000053450 TM35_000043520 TM35_000043520 TM35_000043920 TM35_000043920 TM35_000045080 TM35_000045080 TM35_000045270 TM35_000045270 TM35_000033890 TM35_000033890 TM35_000034240 TM35_000034240 TM35_000021800 TM35_000021800 TM35_000022070 TM35_000022070 TM35_000022510 TM35_000022510 TM35_000022910 TM35_000022910 TM35_000023940 TM35_000023940 TM35_000034230 TM35_000034230 TM35_000025370 TM35_000025370 TM35_000022950 TM35_000022950 TM35_000011120 TM35_000011120 TM35_000024550 TM35_000024550 TM35_000024750 TM35_000024750 TM35_000014230 TM35_000014230 TM35_000014830 TM35_000014830 TM35_000016030 TM35_000016030 TM35_000015020 TM35_000015020 TM35_000016310 TM35_000016310 TM35_000017110 TM35_000017110 TM35_000017030 TM35_000017030
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TM35_000082250Metallophos domain-containing protein. (482 aa)
TM35_003131000DNA-directed RNA polymerase subunit. (142 aa)
TM35_000791060Poly [ADP-ribose] polymerase. (589 aa)
TM35_000721050Uncharacterized protein. (486 aa)
TM35_000721060Protein kinase domain-containing protein. (278 aa)
TM35_000631030Putative recombination initiation protein NBS1. (1033 aa)
TM35_000721130Putative TPR-repeat protein. (482 aa)
TM35_000461310AAA ATPase. (1272 aa)
TM35_000481220Mitochondrial structure specific endonuclease I (SSE-1). (295 aa)
TM35_000491140Fe2OG dioxygenase domain-containing protein. (305 aa)
TM35_000431750Transcription elongation factor. (243 aa)
TM35_000401090Putative GTP cyclohydrolase II. (158 aa)
TM35_000401310FHA domain-containing protein. (862 aa)
TM35_000401790Putative mitochondrial DNA polymerase I protein D. (1631 aa)
TM35_000401720Putative phosphoprotein phosphatase. (556 aa)
TM35_000391390Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (100 aa)
TM35_000391790Phosphatidylinositol kinase related protein; Belongs to the PI3/PI4-kinase family. (4400 aa)
TM35_000451680Uncharacterized protein. (420 aa)
TM35_0004416503'-5' exonuclease domain-containing protein. (749 aa)
TM35_000401650Putative DNA cross-link repair 1A protein. (546 aa)
TM35_000391650Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family. (277 aa)
TM35_000431780ATPase domain protein; Belongs to the AAA ATPase family. (520 aa)
TM35_000381330CYC2-like cyclin. (573 aa)
TM35_000411090DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1201 aa)
TM35_000361360Basic immunoglobulin-like variable motif-containing protein. (511 aa)
TM35_000371260Pre-mRNA-splicing factor ISY1. (260 aa)
TM35_000341640Putative ubiquitin fusion degardation protein. (310 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (393 aa)
TM35_000332090Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (524 aa)
TM35_000332020CULLIN_2 domain-containing protein; Belongs to the cullin family. (989 aa)
TM35_000332030MPN domain-containing protein. (414 aa)
TM35_000371930Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1067 aa)
TM35_000332180Putative DNA polymerase delta subunit 2. (562 aa)
TM35_000341410Replication factor C, subunit 5. (349 aa)
TM35_000341620PCI domain-containing protein. (317 aa)
TM35_000301640Putative ubiquitin-like protein. (704 aa)
TM35_000291740DNA excision repair protein. (1215 aa)
TM35_000291670Putative mitochondrial DNA polymerase I protein C. (1724 aa)
TM35_000302030Putative RNA helicase. (2228 aa)
TM35_000281700Small ubiquitin protein. (116 aa)
TM35_000281980DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (403 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (258 aa)
TM35_000292350VWFA domain-containing protein. (843 aa)
TM35_000281990Putative mitochondrial DNA polymerase beta-PAK. (703 aa)
TM35_000261960Cullin-4B; Belongs to the cullin family. (890 aa)
TM35_000251380COP9 signalosome complex subunit 6. (411 aa)
TM35_000281360DNA repair protein. (1268 aa)
TM35_000251340Uncharacterized protein. (753 aa)
TM35_000251390AKAP7_NLS domain-containing protein. (453 aa)
TM35_000242460Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (473 aa)
TM35_000241380Alkylated DNA repair protein alkB like protein 7. (280 aa)
TM35_000231630Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (839 aa)
TM35_000242080Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (465 aa)
TM35_000232050Uncharacterized protein. (536 aa)
TM35_000232380Tyrosyl-DNA Phosphodiesterase (Tdp1). (547 aa)
TM35_000251850Deaminase. (205 aa)
TM35_000232040Putative transcription elongation factor-like protein. (477 aa)
TM35_000222830DNA repair helicase, TFIIH complex, XPB subunit. (778 aa)
TM35_000241490Serine/threonine-protein phosphatase. (277 aa)
TM35_000211480DNA ligase. (522 aa)
TM35_000221970Serine/threonine-protein phosphatase. (303 aa)
TM35_000211470DNA ligase. (524 aa)
TM35_000212550Oxidoreductase. (432 aa)
TM35_000182630Mismatch repair protein MSH3. (991 aa)
TM35_000172070Phosphatidylinositol 3-related kinase; Belongs to the PI3/PI4-kinase family. (2859 aa)
TM35_000172380Ubiquitin hydrolase; Belongs to the peptidase C19 family. (446 aa)
TM35_000172130RNA helicase. (1350 aa)
TM35_000173060A kinase (PRKA) anchor protein 7. (268 aa)
TM35_000191040Putative DNA repair protein. (268 aa)
TM35_000173170Uncharacterized protein. (459 aa)
TM35_000172350RNA polymerase-like protein. (190 aa)
TM35_000162320DNA repair protein. (396 aa)
TM35_000172850Cyclin; Belongs to the cyclin family. (189 aa)
TM35_000151130DNA polymerase theta (Polymerase domain only). (977 aa)
TM35_000182660Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (285 aa)
TM35_000151230Replication factor C, subunit 1. (593 aa)
TM35_000171610CBFD_NFYB_HMF domain-containing protein. (142 aa)
TM35_000152160ATP-dependent DEAD/H DNA helicase recQ. (1604 aa)
TM35_000152670Cyclin-dependent protein kinase. (506 aa)
TM35_000152660Uncharacterized protein. (827 aa)
TM35_000152120DNA repair protein. (649 aa)
TM35_000151990Mismatch repair protein MLH1. (974 aa)
TM35_000153090DNA repair helicase, TFIIH complex, XPD subunit. (823 aa)
TM35_000141920ATPase_AAA_core domain-containing protein. (1320 aa)
TM35_000142970DNA repair protein BRCA2. (1082 aa)
TM35_000131380Putative ATP-dependent RNA helicase. (1189 aa)
TM35_000162770DNA-direcetd RNA polymerase II, subunit 9. (133 aa)
TM35_000162870Histone H2B; Belongs to the histone H2B family. (143 aa)
TM35_000131050Pre-mRNA-splicing factor SYF1. (778 aa)
TM35_000133010DUF1767 domain-containing protein. (274 aa)
TM35_000152400DNA repair and transcription factor protein, TFIIH complex, SSL1 subunit. (358 aa)
TM35_000131520Uncharacterized protein. (814 aa)
TM35_000121210DNA topoisomerase IA. (855 aa)
TM35_000141300Cell division cycle protein. (710 aa)
TM35_000111200Putative proteasome regulatory non-ATPase subunit 6. (442 aa)
TM35_000111390Transcription activator. (980 aa)
TM35_000131440DNA polymerase zeta catalytic subunit. (2021 aa)
TM35_000112600DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (149 aa)
TM35_000112900Putative DNA repair protein RAD50. (1358 aa)
TM35_000112880DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (376 aa)
TM35_000113400Putative DNA polymerase kappa, putative,DNA polymerase IV. (609 aa)
TM35_000113420DNA polymerase kappa. (513 aa)
TM35_000113470Putative ATPase. (630 aa)
TM35_000101990Metallopeptidase. (397 aa)
TM35_000091160DNA-directed RNA polymerase II subunit 3. (337 aa)
TM35_000102260Putative recombination initiation protein NBS1. (1000 aa)
TM35_000092720UBA domain-containing protein. (350 aa)
TM35_000091630DNA repair helicase and transcription factor protein. (926 aa)
TM35_000091490DNA repair protein. (496 aa)
TM35_000083330Putative CYC2-like cyclin, putative,G1 cyclin CycE4. (1199 aa)
TM35_000071500UV excision repair RAD23-like protein. (366 aa)
TM35_000082810Putative DNA mismatch repair protein MSH2. (956 aa)
TM35_000084560Putative transcription activator. (1121 aa)
TM35_000092900Topoisomerase (DNA) II binding protein 1. (803 aa)
TM35_000071050Putative damage-specific DNA binding protein. (1275 aa)
TM35_000072480Putative Transitional endoplasmic reticulum ATPase. (784 aa)
TM35_000072690Putative ATP-dependent DEAD/H DNA helicase recQ family. (954 aa)
TM35_000074980Putative polynucleotide kinase 3-phosphatase. (486 aa)
TM35_000061310Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (100 aa)
TM35_000062320Flagellar/basal body protein. (236 aa)
TM35_000071140Cyclin; Belongs to the cyclin family. (218 aa)
TM35_000071340DNA ligase. (707 aa)
TM35_000074770Putative KU80 protein. (841 aa)
TM35_000072340Putative replication factor C, subunit 2. (347 aa)
TM35_000064870DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (931 aa)
TM35_000064830Replication factor C, subunit 4. (342 aa)
TM35_000062340DNA excision/repair protein SNF2. (715 aa)
TM35_000052120Putative Transitional endoplasmic reticulum ATPase. (657 aa)
TM35_000054330COP9 signalosome complex subunit 7, variant. (189 aa)
TM35_000054580Putative DNA-directed RNA polymerase subunit. (132 aa)
TM35_000042380DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2271 aa)
TM35_000054090Putative CYC2-like cyclin 6. (270 aa)
TM35_000043160Putative DNA repair protein RAD2. (754 aa)
TM35_000043310Putative DNA-repair protein. (771 aa)
TM35_000053450Putative DNA-directed RNA polymerase II. (132 aa)
TM35_000043520Replication factor C, subunit 3. (359 aa)
TM35_000043920Putative poly(ADP-ribose) glycohydrolase. (590 aa)
TM35_000045080Mismatch repair protein PMS1. (821 aa)
TM35_000045270DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (535 aa)
TM35_000033890Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (294 aa)
TM35_000034240DNA-directed RNA polymerase II. (293 aa)
TM35_000021800Putative serine/threonine protein kinase. (945 aa)
TM35_000022070O-6 methyl-guanine alkyl transferase. (247 aa)
TM35_000022510Uncharacterized protein. (529 aa)
TM35_000022910Serine/threonine-protein phosphatase. (759 aa)
TM35_000023940Putative Transitional endoplasmic reticulum ATPase. (780 aa)
TM35_000034230Putative DNA-directed RNA polymerases II. (219 aa)
TM35_000025370Putative DNA damage repair protein. (632 aa)
TM35_000022950Mismatch repair protein MSH6. (1061 aa)
TM35_000011120Uncharacterized protein. (520 aa)
TM35_000024550General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (503 aa)
TM35_000024750Small subunit ribosomal protein S27Ae. (151 aa)
TM35_000014230Mitochondrial DNA polymerase I protein A. (986 aa)
TM35_0000148308-oxoguanine DNA glycosylase. (447 aa)
TM35_000016030DNA cross-link repair 1A protein. (741 aa)
TM35_000015020Asparaginyl-tRNA synthetase. (748 aa)
TM35_000016310RuvB-like helicase; Belongs to the RuvB family. (459 aa)
TM35_000017110Uncharacterized protein. (459 aa)
TM35_000017030Rep_fac-A_C domain-containing protein. (574 aa)
Your Current Organism:
Trypanosoma theileri
NCBI taxonomy Id: 67003
Other names: T. theileri
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