31 items (Trypanosoma theileri) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TM35_000431940	Putative clathrin coat assembly protein. (500 aa)
	TM35_000015010	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (143 aa)
	TM35_000023460	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1706 aa)
	TM35_000024750	Small subunit ribosomal protein S27Ae. (151 aa)
	TM35_000011120	Uncharacterized protein. (520 aa)
	TM35_000024810	Ubiquitin-like protein. (293 aa)
	TM35_000025300	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (181 aa)
	TM35_000022510	Uncharacterized protein. (529 aa)
	TM35_000031440	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
	TM35_000054010	Epsin. (517 aa)
	TM35_000054330	COP9 signalosome complex subunit 7, variant. (189 aa)
	TM35_000052540	Ubiquilin. (393 aa)
	TM35_000064930	ADP-ribosylation factor GTPase activating protein. (449 aa)
	TM35_000073330	AAA domain-containing protein. (882 aa)
	TM35_000074500	Putative LMBR1-like membrane protein. (586 aa)
	TM35_000101990	Metallopeptidase. (397 aa)
	TM35_000111200	Putative proteasome regulatory non-ATPase subunit 6. (442 aa)
	TM35_000181950	Protein kinase. (755 aa)
	TM35_000212890	Putative zinc finger protein. (310 aa)
	TM35_000232570	Putative ATP-dependent Clp protease subunit; Belongs to the ClpA/ClpB family. (868 aa)
	TM35_000231670	Putative paraflagellar rod protein. (789 aa)
	TM35_000251940	Protein kinase. (1203 aa)
	TM35_000251380	COP9 signalosome complex subunit 6. (411 aa)
	TM35_000301640	Putative ubiquitin-like protein. (704 aa)
	TM35_000341620	PCI domain-containing protein. (317 aa)
	TM35_000311220	AAA domain-containing protein. (442 aa)
	TM35_000371220	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (971 aa)
	TM35_000371860	AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family. (416 aa)
	TM35_000391200	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (180 aa)
	TM35_000391090	ATP-dependent Clp protease subunit, heat shock protein 78. (803 aa)
	TM35_000421630	GTP-ase activating protein. (588 aa)

Your Current Organism:

Trypanosoma theileri

NCBI taxonomy Id: 67003
Other names: T. theileri

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TM35_000011120	TM35_000022510	A0A1X0P8T1	A0A1X0P7V2	Uncharacterized protein.	Uncharacterized protein.	0.999
TM35_000011120	TM35_000024750	A0A1X0P8T1	A0A1X0P981	Uncharacterized protein.	Small subunit ribosomal protein S27Ae.	0.734
TM35_000011120	TM35_000024810	A0A1X0P8T1	A0A1X0P8J6	Uncharacterized protein.	Ubiquitin-like protein.	0.641
TM35_000011120	TM35_000052540	A0A1X0P8T1	A0A1X0P4A2	Uncharacterized protein.	Ubiquilin.	0.641
TM35_000011120	TM35_000054330	A0A1X0P8T1	A0A1X0P4H5	Uncharacterized protein.	COP9 signalosome complex subunit 7, variant.	0.997
TM35_000011120	TM35_000101990	A0A1X0P8T1	A0A1X0NZA6	Uncharacterized protein.	Metallopeptidase.	0.999
TM35_000011120	TM35_000111200	A0A1X0P8T1	A0A1X0NY12	Uncharacterized protein.	Putative proteasome regulatory non-ATPase subunit 6.	0.999
TM35_000011120	TM35_000251380	A0A1X0P8T1	A0A1X0NQ45	Uncharacterized protein.	COP9 signalosome complex subunit 6.	0.999
TM35_000011120	TM35_000301640	A0A1X0P8T1	A0A1X0NN39	Uncharacterized protein.	Putative ubiquitin-like protein.	0.734
TM35_000011120	TM35_000341620	A0A1X0P8T1	A0A1X0NN26	Uncharacterized protein.	PCI domain-containing protein.	0.999
TM35_000015010	TM35_000023460	A0A1X0P9M2	A0A1X0P986	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.934
TM35_000015010	TM35_000024750	A0A1X0P9M2	A0A1X0P981	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Small subunit ribosomal protein S27Ae.	0.590
TM35_000015010	TM35_000024810	A0A1X0P9M2	A0A1X0P8J6	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Ubiquitin-like protein.	0.538
TM35_000015010	TM35_000052540	A0A1X0P9M2	A0A1X0P4A2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Ubiquilin.	0.538
TM35_000015010	TM35_000054010	A0A1X0P9M2	A0A1X0P4K8	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Epsin.	0.775
TM35_000015010	TM35_000181950	A0A1X0P9M2	A0A1X0NUC1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Protein kinase.	0.494
TM35_000015010	TM35_000212890	A0A1X0P9M2	A0A1X0NT87	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Putative zinc finger protein.	0.740
TM35_000015010	TM35_000251940	A0A1X0P9M2	A0A1X0NQU2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Protein kinase.	0.494
TM35_000015010	TM35_000301640	A0A1X0P9M2	A0A1X0NN39	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Putative ubiquitin-like protein.	0.590
TM35_000015010	TM35_000371220	A0A1X0P9M2	A0A1X0NLY4	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.999