(5 nodes) Lipopolysaccharide biosynthesis network (Hyphomicrobium denitrificans 1NES1)

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Your Input:
	kdsA	2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. (288 aa)
	AGK58977.1	3-deoxy-D-manno-octulosonic-acid transferase; COG2121 Uncharacterized protein conserved in bacteria. (689 aa)
	lpxK	Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (342 aa)
	AGK59054.1	KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. (343 aa)
	kdsB	3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (249 aa)

Your Current Organism:

Hyphomicrobium denitrificans 1NES1

NCBI taxonomy Id: 670307
Other names: H. denitrificans 1NES1, Hyphomicrobium denitrificans str. 1NES1, Hyphomicrobium denitrificans strain 1NES1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGK58977.1	AGK59054.1	HYPDE_36528	HYPDE_36913	3-deoxy-D-manno-octulosonic-acid transferase; COG2121 Uncharacterized protein conserved in bacteria.	KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily.	0.890
AGK58977.1	kdsA	HYPDE_36528	HYPDE_31368	3-deoxy-D-manno-octulosonic-acid transferase; COG2121 Uncharacterized protein conserved in bacteria.	2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family.	0.839
AGK58977.1	kdsB	HYPDE_36528	HYPDE_37408	3-deoxy-D-manno-octulosonic-acid transferase; COG2121 Uncharacterized protein conserved in bacteria.	3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.	0.983
AGK58977.1	lpxK	HYPDE_36528	HYPDE_36533	3-deoxy-D-manno-octulosonic-acid transferase; COG2121 Uncharacterized protein conserved in bacteria.	Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	0.997
AGK59054.1	AGK58977.1	HYPDE_36913	HYPDE_36528	KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily.	3-deoxy-D-manno-octulosonic-acid transferase; COG2121 Uncharacterized protein conserved in bacteria.	0.890
AGK59054.1	kdsA	HYPDE_36913	HYPDE_31368	KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily.	2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family.	0.989
AGK59054.1	kdsB	HYPDE_36913	HYPDE_37408	KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily.	3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.	0.892
AGK59054.1	lpxK	HYPDE_36913	HYPDE_36533	KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily.	Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	0.890
kdsA	AGK58977.1	HYPDE_31368	HYPDE_36528	2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family.	3-deoxy-D-manno-octulosonic-acid transferase; COG2121 Uncharacterized protein conserved in bacteria.	0.839
kdsA	AGK59054.1	HYPDE_31368	HYPDE_36913	2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family.	KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily.	0.989
kdsA	kdsB	HYPDE_31368	HYPDE_37408	2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family.	3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.	0.858
kdsA	lpxK	HYPDE_31368	HYPDE_36533	2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family.	Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	0.855
kdsB	AGK58977.1	HYPDE_37408	HYPDE_36528	3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.	3-deoxy-D-manno-octulosonic-acid transferase; COG2121 Uncharacterized protein conserved in bacteria.	0.983
kdsB	AGK59054.1	HYPDE_37408	HYPDE_36913	3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.	KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily.	0.892
kdsB	kdsA	HYPDE_37408	HYPDE_31368	3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.	2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family.	0.858
kdsB	lpxK	HYPDE_37408	HYPDE_36533	3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.	Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	0.856
lpxK	AGK58977.1	HYPDE_36533	HYPDE_36528	Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	3-deoxy-D-manno-octulosonic-acid transferase; COG2121 Uncharacterized protein conserved in bacteria.	0.997
lpxK	AGK59054.1	HYPDE_36533	HYPDE_36913	Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily.	0.890
lpxK	kdsA	HYPDE_36533	HYPDE_31368	Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family.	0.855
lpxK	kdsB	HYPDE_36533	HYPDE_37408	Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.	0.856