STRINGSTRING
AGK56767.1 AGK56767.1 ubiE ubiE AGK60029.1 AGK60029.1 ubiG ubiG AGK59709.1 AGK59709.1 AGK59704.1 AGK59704.1 AGK59648.1 AGK59648.1 gloB gloB ubiA ubiA AGK58895.1 AGK58895.1 AGK58669.1 AGK58669.1 AGK58605.1 AGK58605.1 pqqE-3 pqqE-3 AGK57918.1 AGK57918.1 pqqC pqqC pqqB-2 pqqB-2 AGK57742.1 AGK57742.1 AGK57728.1 AGK57728.1 AGK57719.1 AGK57719.1 AGK57666.1 AGK57666.1 AGK57593.1 AGK57593.1 AGK57498.1 AGK57498.1 pqqE-2 pqqE-2 pqqB pqqB AGK57155.1 AGK57155.1 AGK56866.1 AGK56866.1 AGK56766.1 AGK56766.1 AGK56765.1 AGK56765.1 AGK56764.1 AGK56764.1 AGK56751.1 AGK56751.1 pqqE pqqE AGK56664.1 AGK56664.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
AGK56767.1Protease; COG0826 Collagenase and related proteases. (299 aa)
ubiEUbiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (259 aa)
AGK60029.12-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. (520 aa)
ubiGUbiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (339 aa)
AGK59709.1Type 11 methyltransferase; COG0500 SAM-dependent methyltransferases. (270 aa)
AGK59704.1Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases. (131 aa)
AGK59648.1COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. (414 aa)
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (269 aa)
ubiA4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (320 aa)
AGK58895.1COG2960 Uncharacterized protein conserved in bacteria. (88 aa)
AGK58669.1Beta-lactamase; COG0491 Zn-dependent hydrolases, including glyoxylases. (321 aa)
AGK58605.1NAD-dependent epimerase/dehydratase; COG0702 Predicted nucleoside-diphosphate-sugar epimerases. (324 aa)
pqqE-3Pyrroloquinoline quinone biosynthesis protein PqqE; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ). (386 aa)
AGK57918.1Coenzyme PQQ synthesis D. (100 aa)
pqqCPyrroloquinoline quinone biosynthesis protein PqqC; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. (258 aa)
pqqB-2Coenzyme PQQ biosynthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family. (326 aa)
AGK57742.1Hypothetical protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. (408 aa)
AGK57728.1Cyclase/dehydrase; COG2867 Oligoketide cyclase/lipid transport protein. (160 aa)
AGK57719.1COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. (418 aa)
AGK57666.1Beta-lactamase; COG0491 Zn-dependent hydrolases, including glyoxylases. (322 aa)
AGK57593.1Hypothetical protein; COG0500 SAM-dependent methyltransferases. (436 aa)
AGK57498.1Beta-lactamase domain-containing protein; COG0491 Zn-dependent hydrolases, including glyoxylases. (302 aa)
pqqE-2Pyrroloquinoline quinone biosynthesis protein PqqE; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ). (383 aa)
pqqBPyrroloquinoline quinone biosynthesis protein PqqC; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family. (563 aa)
AGK57155.1Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases. (365 aa)
AGK56866.1Beta-lactamase domain-containing protein; COG0491 Zn-dependent hydrolases, including glyoxylases. (338 aa)
AGK56766.1Peptidase U32; COG0826 Collagenase and related proteases. (327 aa)
AGK56765.1COG3154 Putative lipid carrier protein. (182 aa)
AGK56764.1UbiD family decarboxylase; COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family. (499 aa)
AGK56751.1Coenzyme PQQ synthesis D. (95 aa)
pqqEPyrroloquinoline quinone biosynthesis protein PqqE; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ). (383 aa)
AGK56664.1Hopanoid biosynthesis associated radical SAM protein HpnH; COG0535 Predicted Fe-S oxidoreductases. (384 aa)
Your Current Organism:
Hyphomicrobium denitrificans 1NES1
NCBI taxonomy Id: 670307
Other names: H. denitrificans 1NES1, Hyphomicrobium denitrificans str. 1NES1, Hyphomicrobium denitrificans strain 1NES1
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