41 items (Heterostelium album) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	apm2	Clathrin-adaptor medium chain AP-2; Belongs to the adaptor complexes medium subunit family. (435 aa)
	tgrF1	IPT/TIG domain-containing protein. (1437 aa)
	nek3	Protein kinase domain-containing protein. (899 aa)
	PPL_05196	Uncharacterized protein. (3030 aa)
	psenen	Gamma-secretase subunit. (97 aa)
	PPL_04695	Calponin-homology (CH) domain-containing protein. (1038 aa)
	PPL_04619	Uncharacterized protein. (1153 aa)
	PPL_04618	Uncharacterized protein. (1450 aa)
	cofC-2	Cofilin-2; Belongs to the actin-binding proteins ADF family. (133 aa)
	PPL_03799	Protein kinase domain-containing protein. (421 aa)
	mekA	MAP kinase kinase. (479 aa)
	PPL_01519	G8 domain-containing protein. (1366 aa)
	wasA	Wiscott-Aldrich syndrome protein. (650 aa)
	aph1	Gamma-secretase subunit Aph-1. (148 aa)
	PPL_00784	LISK family protein kinase. (732 aa)
	PPL_00585	G8 domain-containing protein. (1231 aa)
	clc	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (212 aa)
	PPL_00390	Uncharacterized protein. (696 aa)
	PPL_11778	PH domain-containing protein. (671 aa)
	ap2a1-2	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (994 aa)
	PPL_11773	G8 domain-containing protein. (1089 aa)
	pakC	Non-specific serine/threonine protein kinase. (490 aa)
	PPL_10671	G8 domain-containing protein. (1108 aa)
	ap2s1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (135 aa)
	PPL_09886	Pleckstrin domain-containing protein. (769 aa)
	PPL_09796	Uncharacterized protein. (2281 aa)
	PPL_09792	Uncharacterized protein. (2248 aa)
	cofB	Cofilin; Belongs to the actin-binding proteins ADF family. (137 aa)
	chcA	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1691 aa)
	wasA-2	Wiscott-Aldrich syndrome protein. (393 aa)
	cdk5	Protein serine/threonine kinase; Belongs to the protein kinase superfamily. (295 aa)
	talA	Filopodin. (2479 aa)
	allB2	Allantoinase. (647 aa)
	PPL_09217	Pleckstrin domain-containing protein. (1086 aa)
	PPL_08812	Uncharacterized protein. (2217 aa)
	ap1b1	AP complex subunit beta. (723 aa)
	frmA	FERM domain-containing protein. (1719 aa)
	PPL_07898	Uncharacterized protein. (131 aa)
	PPL_07659	G8 domain-containing protein. (1404 aa)
	PPL_07294	G8 domain-containing protein. (1412 aa)
	hspD	Heat shock protein Hsp90 family protein. (699 aa)

Your Current Organism:

Heterostelium album

NCBI taxonomy Id: 670386
Other names: H. album PN500, Heterostelium album PN500, Heterostelium pallidum PN500, Polysphondylium pallidum PN500

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PPL_00390	chcA	D3AWB6	D3BNB1	Uncharacterized protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.707
PPL_00390	clc	D3AWB6	D3AVG6	Uncharacterized protein.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.680
PPL_00585	cdk5	D3AWV7	D3BMU7	G8 domain-containing protein.	Protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.409
PPL_00784	cdk5	D3AXF3	D3BMU7	LISK family protein kinase.	Protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.417
PPL_00784	cofB	D3AXF3	D3BNF6	LISK family protein kinase.	Cofilin; Belongs to the actin-binding proteins ADF family.	0.527
PPL_00784	cofC-2	D3AXF3	D3B726	LISK family protein kinase.	Cofilin-2; Belongs to the actin-binding proteins ADF family.	0.527
PPL_00784	hspD	D3AXF3	D3BEQ3	LISK family protein kinase.	Heat shock protein Hsp90 family protein.	0.718
PPL_00784	mekA	D3AXF3	D3AZU5	LISK family protein kinase.	MAP kinase kinase.	0.584
PPL_00784	pakC	D3AXF3	D3BSW5	LISK family protein kinase.	Non-specific serine/threonine protein kinase.	0.745
PPL_01519	cdk5	D3AZH7	D3BMU7	G8 domain-containing protein.	Protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.409
PPL_04618	cdk5	D3B828	D3BMU7	Uncharacterized protein.	Protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.409
PPL_04619	cdk5	D3B829	D3BMU7	Uncharacterized protein.	Protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.409
PPL_04695	chcA	D3B8A4	D3BNB1	Calponin-homology (CH) domain-containing protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.421
PPL_05196	cdk5	D3B9Q0	D3BMU7	Uncharacterized protein.	Protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.409
PPL_07294	cdk5	D3BEX8	D3BMU7	G8 domain-containing protein.	Protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.409
PPL_07659	cdk5	D3BGK7	D3BMU7	G8 domain-containing protein.	Protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.409
PPL_07898	mekA	D3BH96	D3AZU5	Uncharacterized protein.	MAP kinase kinase.	0.695
PPL_08812	cdk5	D3BJT2	D3BMU7	Uncharacterized protein.	Protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.409
PPL_09217	chcA	D3BKY5	D3BNB1	Pleckstrin domain-containing protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.421
PPL_09792	cdk5	D3BP29	D3BMU7	Uncharacterized protein.	Protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.409