110 items (Heterostelium album) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pex10	RING zinc finger-containing protein. (372 aa)
	PPL_10984	Insulin-degrading enzyme; Belongs to the peptidase M16 family. (634 aa)
	PPL_10930	MCD domain-containing protein. (192 aa)
	PPL_10793	Major sperm protein domain-containing protein. (351 aa)
	hao	Hydroxyacid oxidase. (366 aa)
	PPL_10620	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (666 aa)
	ech1	Enoyl Coenzyme A hydratase. (300 aa)
	PPL_10496	Esterase/lipase/thioesterase domain-containing protein. (246 aa)
	PPL_10445	CoA-transferase family III protein. (422 aa)
	PPL_10433	Glycolate oxidase subunit D-like protein. (558 aa)
	pitrm1	Peptidase M16 family protein. (1031 aa)
	coq2	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (462 aa)
	bcs1lA	Mitochondrial chaperone BCS1; Belongs to the AAA ATPase family. (439 aa)
	sgtA	Tetratricopeptide-like helical domain-containing protein. (352 aa)
	PPL_09970	Acetyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (419 aa)
	pex11	Transmembrane protein. (152 aa)
	grpE	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (232 aa)
	pex5	Tetratricopeptide-like helical domain-containing protein. (793 aa)
	agps	Alkyl-dihydroxyacetonephosphate synthase. (618 aa)
	PPL_12555	Peptidase S16; Belongs to the peptidase S16 family. (1283 aa)
	PPL_12464	AAA ATPase domain-containing protein. (405 aa)
	PPL_12282	Ubiquitin domain-containing protein; Belongs to the peptidase C19 family. (2735 aa)
	PPL_12184	AAA ATPase domain-containing protein; Belongs to the AAA ATPase family. (336 aa)
	PPL_09190	Uncharacterized protein. (147 aa)
	PPL_09184	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (669 aa)
	pex6	AAA ATPase domain-containing protein. (1293 aa)
	timm10	Mitochondrial import inner membrane translocase subunit 10. (93 aa)
	PPL_08889	Uncharacterized protein. (282 aa)
	PPL_08800	Pmp22 family protein. (537 aa)
	PPL_08743	Pmp22 family protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (164 aa)
	timm16	Presequence translocated-associated motor subunit. (110 aa)
	PPL_08601	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (617 aa)
	acoA	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (657 aa)
	hmgL	Hydroxymethylglutaryl-CoA lyase. (353 aa)
	PPL_08011	Uncharacterized protein. (286 aa)
	PPL_07987	Uncharacterized protein. (143 aa)
	PPL_07943	AB hydrolase-1 domain-containing protein. (345 aa)
	PPL_07928	DAO domain-containing protein. (457 aa)
	PPL_07808	Tafazzin isoform 8-like protein. (871 aa)
	PPL_07773	Uncharacterized protein. (763 aa)
	PPL_07639	Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	PPL_07619	DUF410 family protein. (303 aa)
	timm17	Mitochondrial import inner membrane translocase subunit 17. (176 aa)
	PPL_06738	Uncharacterized protein. (196 aa)
	PPL_07236	Uncharacterized protein; Belongs to the peptidase M16 family. (846 aa)
	PPL_07124	Acetyltransferase. (201 aa)
	idhC	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (509 aa)
	PPL_07035	Uncharacterized protein. (858 aa)
	PPL_06449	Uncharacterized protein. (58 aa)
	PPL_06347	Tim44 domain-containing protein. (528 aa)
	PPL_06346	Ubiquitin-like domain-containing protein. (724 aa)
	abcD2	ABC transporter D family protein. (735 aa)
	syn5	t-SNARE family protein. (334 aa)
	PPL_05933	Nudix hydrolase domain-containing protein. (292 aa)
	pex7	WD40 repeat-containing protein. (333 aa)
	PPL_05737	Ubiquitin-like domain-containing protein. (149 aa)
	PPL_05561	TPR_REGION domain-containing protein. (970 aa)
	pex16	Peroxisomal membrane protein PEX16. (323 aa)
	PPL_05542	TPR_REGION domain-containing protein. (318 aa)
	PPL_05239	Uncharacterized protein. (273 aa)
	bcs1lB	Mitochondrial chaperone BCS1. (464 aa)
	ubqI	Ubiquitin. (443 aa)
	PPL_04810	Stress-response A/B barrel domain-containing protein. (158 aa)
	PPL_04691	Phytanoyl-CoA dioxygenase family protein. (302 aa)
	pex12	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. (390 aa)
	PPL_04362	Uncharacterized protein. (662 aa)
	PPL_04281	UBIQUITIN_CONJUGAT_2 domain-containing protein. (230 aa)
	catA	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (496 aa)
	dnajc19	Mitochondrial import inner membrane translocase subunit 14. (111 aa)
	ddo-1	D-aspartate oxidase. (359 aa)
	PPL_00285	Uncharacterized protein. (1074 aa)
	agxt	Serine-pyruvate transaminase. (405 aa)
	pex3	Peroxisomal biogenesis factor 3. (420 aa)
	PPL_00684	Oxalyl-CoA decarboxylase; Belongs to the TPP enzyme family. (565 aa)
	PPL_00728	ACOX domain-containing protein. (343 aa)
	PPL_00839	SRR1 domain-containing protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (604 aa)
	PPL_01227	Uncharacterized protein. (385 aa)
	pex19	Peroxin 19. (304 aa)
	PPL_01548	KxDL domain-containing protein. (727 aa)
	PPL_01734	Uncharacterized protein. (557 aa)
	PPL_01800	Lon protease homolog; Belongs to the peptidase S16 family. (920 aa)
	PPL_01942	Uncharacterized protein. (632 aa)
	idhM	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (472 aa)
	PPL_02343	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (354 aa)
	PPL_02650	Sulfhydryl oxidase. (201 aa)
	ancA	ADP/ATP translocase; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa)
	sec61g	Protein transport protein SEC61 gamma subunit. (69 aa)
	PPL_02895	Transmembrane protein. (267 aa)
	hspA	Chaperonin 60; Belongs to the chaperonin (HSP60) family. (558 aa)
	pex13	SH3 domain-containing protein. (524 aa)
	arsA	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] (341 aa)
	atp5b	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (704 aa)
	sybB	Synaptobrevin domain-containing protein. (93 aa)
	PPL_03370	Uncharacterized protein. (161 aa)
	PPL_03400	ADP/ATP translocase; Belongs to the mitochondrial carrier (TC 2.A.29) family. (292 aa)
	redB	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450. (669 aa)
	PPL_03578	Uncharacterized protein. (140 aa)
	mcfQ	Transmembrane protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (334 aa)
	mgm101	Mitochondrial genome maintenance protein. (406 aa)
	mfeB	Hypothetical peroxisomal multifunctional enzyme 2. (294 aa)
	pex1	Peroxisomal biogenesis factor 1. (1212 aa)
	ilvB	Thiamine pyrophosphate-binding enzyme family protein; Belongs to the TPP enzyme family. (630 aa)
	PPL_11603	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (690 aa)
	PPL_11602	Uncharacterized protein. (403 aa)
	PPL_11890	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (639 aa)
	PPL_11501	Nudix hydrolase domain-containing protein. (334 aa)
	PPL_11461	Uncharacterized protein. (64 aa)
	pex14	Transmembrane protein. (726 aa)
	PPL_11120	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (646 aa)
	comG	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (506 aa)

Your Current Organism:

Heterostelium album

NCBI taxonomy Id: 670386
Other names: H. album PN500, Heterostelium album PN500, Heterostelium pallidum PN500, Polysphondylium pallidum PN500

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PPL_00285	PPL_00684	D3AW18	D3AX55	Uncharacterized protein.	Oxalyl-CoA decarboxylase; Belongs to the TPP enzyme family.	0.402
PPL_00285	PPL_01734	D3AW18	D3B0B8	Uncharacterized protein.	Uncharacterized protein.	0.458
PPL_00285	PPL_04281	D3AW18	D3B747	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.500
PPL_00285	PPL_05737	D3AW18	D3BB06	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.924
PPL_00285	PPL_06346	D3AW18	D3BCW8	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.476
PPL_00285	PPL_07236	D3AW18	D3BES1	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase M16 family.	0.458
PPL_00285	PPL_07619	D3AW18	D3BGG8	Uncharacterized protein.	DUF410 family protein.	0.511
PPL_00285	PPL_07639	D3AW18	D3BGI7	Uncharacterized protein.	Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.	0.523
PPL_00285	PPL_07773	D3AW18	D3BGX1	Uncharacterized protein.	Uncharacterized protein.	0.458
PPL_00285	PPL_08889	D3AW18	D3BK08	Uncharacterized protein.	Uncharacterized protein.	0.685
PPL_00285	PPL_09970	D3AW18	D3BPS6	Uncharacterized protein.	Acetyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.418
PPL_00285	PPL_10984	D3AW18	D3BSL5	Uncharacterized protein.	Insulin-degrading enzyme; Belongs to the peptidase M16 family.	0.458
PPL_00285	PPL_11603	D3AW18	D3BV78	Uncharacterized protein.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.450
PPL_00285	PPL_12282	D3AW18	D3BM73	Uncharacterized protein.	Ubiquitin domain-containing protein; Belongs to the peptidase C19 family.	0.492
PPL_00285	agps	D3AW18	D3BNP6	Uncharacterized protein.	Alkyl-dihydroxyacetonephosphate synthase.	0.434
PPL_00285	agxt	D3AW18	D3AWU9	Uncharacterized protein.	Serine-pyruvate transaminase.	0.449
PPL_00285	arsA	D3AW18	D3B3Z0	Uncharacterized protein.	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	0.564
PPL_00285	catA	D3AW18	D3B731	Uncharacterized protein.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.441
PPL_00285	hao	D3AW18	D3BRV9	Uncharacterized protein.	Hydroxyacid oxidase.	0.440
PPL_00285	hmgL	D3AW18	D3BHS9	Uncharacterized protein.	Hydroxymethylglutaryl-CoA lyase.	0.414